2GVC
Crystal structure of flavin-containing monooxygenase (FMO)from S.pombe and substrate (methimazole) complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D, E | monooxygenase | polymer | 447 | 50179.5 | 4 | UniProt (Q9HFE4) Pfam (PF13450) Pfam (PF00743) In PDB | Schizosaccharomyces pombe (fission yeast) | |
| 2 | A, B, D, E | HYDROGEN PEROXIDE | non-polymer | 34.0 | 4 | Chemie (PEO) | |||
| 3 | A, B, D, E | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 4 | A, B, D, E | 1-METHYL-1,3-DIHYDRO-2H-IMIDAZOLE-2-THIONE | non-polymer | 114.2 | 4 | Chemie (MMZ) | |||
| 5 | A, B, D, E | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 537 | Chemie (HOH) |
Sequence modifications
A, B, D, E: 1 - 447 (UniProt: Q9HFE4)
| PDB | External Database | Details |
|---|---|---|
| Mse 1 | Met 1 | modified residue |
| Mse 97 | Met 97 | modified residue |
| Mse 377 | Met 377 | modified residue |
| Mse 386 | Met 386 | modified residue |
| Mse 433 | Met 433 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 200718.2 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 4103.3 | |
| All* | Total formula weight | 204821.5 |
