2FSV
Structure of transhydrogenase (dI.D135N.NAD+)2(dIII.E155W.NADP+)1 asymmetric complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | NAD(P) transhydrogenase subunit alpha part 1 | polymer | 384 | 40323.8 | 2 | UniProt (Q60164) Pfam (PF05222) Pfam (PF01262) UniProt (by SIFTS) (Q2RSB2) In PDB | Rhodospirillum rubrum | Pyridine nucleotide transhydrogenase subunit alpha 1, Nicotinamide nucleotide transhydrogenase subunit alpha 1, Proton-translocating transhydrogenase component 1, dI |
| 2 | C | NAD(P) transhydrogenase subunit beta | polymer | 203 | 21542.6 | 1 | UniProt (Q59765) Pfam (PF02233) UniProt (by SIFTS) (P0C188) In PDB | Rhodospirillum rubrum | Pyridine nucleotide transhydrogenase subunit beta, Nicotinamide nucleotide transhydrogenase subunit beta, Proton-translocating transhydrogenase NADPH, -binding component, dIII |
| 3 | A | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | C | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 6 | water | water | 18.0 | 382 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 384 (UniProt: Q60164)
C: 1 - 203 (UniProt: Q59765)
| PDB | External Database | Details |
|---|---|---|
| Asn 135 | Asp 135 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Trp 155 | Glu 416 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 102190.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1683.1 | |
| All* | Total formula weight | 103873.3 |
