2D7I

Crystal structure of pp-GalNAc-T10 with UDP, GalNAc and Mn2+

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Polypeptide N-acetylgalactosaminyltransferase 10	polymer	570	65472.3	1	UniProt (Q86SR1) Pfam (PF00535) Pfam (PF00652) In PDB	Homo sapiens (human)	Protein-UDP acetylgalactosaminyltransferase 10, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10, Polypeptide GalNAc transferase 10, GalNAc-T10, pp-GaNTase 10
2	B	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
3	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
4	A	2-acetamido-2-deoxy-beta-D-galactopyranose	non-polymer		221.2	1	Chemie (NGA)
5	A	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
6	A	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	1	Chemie (UDP)
7		water	water		18.0	237	Chemie (HOH)

Sequence modifications

A: 40 - 603 (UniProt: Q86SR1)

PDB	External Database	Details
His 34	-	expression tag
His 35	-	expression tag
His 36	-	expression tag
His 37	-	expression tag
His 38	-	expression tag
His 39	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	65472.3
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	5
	Total formula weight	1122.7
All*	Total formula weight	67019.4

*Water molecules are not included.