2D7I

Crystal structure of pp-GalNAc-T10 with UDP, GalNAc and Mn2+

Summary for 2D7I

• Entry DOI: 10.2210/pdb2d7i/pdb
• Related: 2D7R
• Descriptor: Polypeptide N-acetylgalactosaminyltransferase 10, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: beta trefoil, rossmann fold, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 67019.43

Authors

Kubota, T.,Shiba, T.,Sugioka, S.,Kato, R.,Wakatsuki, S.,Narimatsu, H. (deposition date: 2005-11-21, release date: 2006-11-07, Last modification date: 2020-07-29)

• Primary citation: Kubota, T.,Shiba, T.,Sugioka, S.,Furukawa, S.,Sawaki, H.,Kato, R.,Wakatsuki, S.,Narimatsu, H.; Structural basis of carbohydrate transfer activity by human UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase (pp-GalNAc-T10); J.Mol.Biol., 359:708-727, 2006; PubMed: 16650853; DOI: 10.1016/j.jmb.2006.03.061

Experimental method

X-RAY DIFFRACTION (2.5 Å)