1YOV
Insights into the Ubiquitin Transfer Cascade from the refined structure of the activating enzyme for NEDD8
Replaces: 1NGVEntity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Amyloid protein-binding protein 1 | polymer | 537 | 60688.6 | 2 | UniProt (Q13564) Pfam (PF00899) In PDB | Homo sapiens (human) | Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Protooncogene protein 1, HPP1 |
2 | B, D | Ubiquitin-activating enzyme E1C | polymer | 444 | 49534.4 | 2 | UniProt (Q8TBC4) Pfam (PF00899) Pfam (PF08825) In PDB | Homo sapiens (human) | Nedd8-activating enzyme E1C, Ubiquitin-activating enzyme 3 homolog |
3 | B, D | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 534 (UniProt: Q13564)
B, D: 1 - 442 (UniProt: Q8TBC4)
PDB | External Database | Details |
---|---|---|
Met -2 | - | cloning artifact |
Lys -1 | - | cloning artifact |
Leu 0 | - | cloning artifact |
PDB | External Database | Details |
---|---|---|
Gly -1 | - | cloning artifact |
Ser 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 220446.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 130.8 | |
All* | Total formula weight | 220577.0 |