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1XHY

X-ray structure of the Y702F mutant of the GluR2 ligand-binding core (S1S2J) in complex with kainate at 1.85 A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AGlutamate receptorpolymer26329205.71UniProt (P19491)
Pfam (PF10613)
Pfam (PF00060)
Pfam (PF00497)
In PDB
Rattus norvegicus (Rat)GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2ASULFATE IONnon-polymer96.15Chemie (SO4)
3A3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINEnon-polymer213.21Chemie (KAI)
4waterwater18.0359Chemie (HOH)
Sequence modifications
A: 0 - 114 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ala -1-expression tag
A: 117 - 260 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 115-linker
Thr 116-linker
Phe 187Tyr 723engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29205.7
Non-Polymers*Number of molecules6
Total formula weight693.5
All*Total formula weight29899.2
*Water molecules are not included.

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PDB entries from 2024-06-12

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