1XHY
X-ray structure of the Y702F mutant of the GluR2 ligand-binding core (S1S2J) in complex with kainate at 1.85 A resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Glutamate receptor | polymer | 263 | 29205.7 | 1 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) Pfam (PF00497) In PDB | Rattus norvegicus (Rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
2 | A | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
3 | A | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE | non-polymer | 213.2 | 1 | Chemie (KAI) | |||
4 | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence modifications
A: 0 - 114 (UniProt: P19491)
A: 117 - 260 (UniProt: P19491)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ala -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 115 | - | linker |
Thr 116 | - | linker |
Phe 187 | Tyr 723 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29205.7 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 693.5 | |
All* | Total formula weight | 29899.2 |