1WEJ

IGG1 FAB FRAGMENT (OF E8 ANTIBODY) COMPLEXED WITH HORSE CYTOCHROME C AT 1.8 A RESOLUTION

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	L	E8 ANTIBODY	polymer	214	23655.1	1	GenBank (2072141) Pfam (PF07686) UniProt (by SIFTS) (P01635) In PDB	Mus musculus (house mouse)	FAB E8
2	H	E8 ANTIBODY	polymer	223	23851.6	1	PIR (S49220)	Mus musculus (house mouse)	FAB E8
3	F	CYTOCHROME C	polymer	105	11751.6	1	UniProt (P00004) Pfam (PF00034) In PDB	Equus caballus (horse)	CYT C, ANTIGEN
4	L	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
5	F	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	1	Chemie (HEM)
6		water	water		18.0	637	Chemie (HOH)

Sequence modifications

L: 1 - 214 (GenBank: 2072141)

PDB	External Database	Details
Ser 85	Thr 99	conflict
Gln 89	His 103	conflict
Ile 106	Val 120	conflict
Phe 118	Leu 132	conflict

H: 2 - 217 (PIR: S49220)

PDB	External Database	Details
Gln 3	Lys 3	conflict
Gln 5	Leu 5	conflict
Gln 6	Glu 6	conflict
Pro 14	Ser 14	conflict
Lys 43	Gln 43	conflict
Ser 55	Asn 55	conflict
Asn 57	Glu 57	conflict
Thr 58	Ile 58	conflict
Asp 66	Gly 66	conflict
Lys 67	Thr 67	conflict
Ser 76	Thr 76	conflict
-	Val 97	deletion
-	Arg 98	deletion
Ala 97	Arg 99	conflict
Asp 100	Gly 102	conflict
Tyr 101	Ser 103	conflict
Gly 102	Ser 104	conflict
Asn 103	Gln 105	conflict
Phe 104	Glu 106	conflict
Asp 105	Pro 107	conflict
Glu 119	Lys 121	conflict
Thr 132	Ser 134	conflict
Leu 135	Gln 137	conflict
Lys 136	Thr 138	conflict
Ser 137	Asn 139	conflict
Thr 182	Ser 184	conflict
Gln 195	Glu 197	conflict

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	59258.3
Non-Polymers*	Number of molecules	2
	Total formula weight	681.9
All*	Total formula weight	59940.2

*Water molecules are not included.