1VG0
The crystal structures of the REP-1 protein in complex with monoprenylated Rab7 protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Rab proteins geranylgeranyltransferase component A 1 | polymer | 650 | 72622.2 | 1 | UniProt (P37727) Pfam (PF00996) In PDB | Rattus norvegicus (Norway rat) | Rab escort protein 1, REP-1 |
| 2 | B | Ras-related protein Rab-7 | polymer | 207 | 23530.7 | 1 | UniProt (P09527) Pfam (PF00071) In PDB | Rattus norvegicus (Norway rat) | RAS-related protein P23, RAS-related protein BRL-RAS |
| 3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | A | GERAN-8-YL GERAN | non-polymer | 274.5 | 1 | Chemie (GER) | |||
| 5 | B | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | B | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 7 | B | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 8 | water | water | 18.0 | 438 | Chemie (HOH) |
Sequence modifications
A: 1 - 650 (UniProt: P37727)
| PDB | External Database | Details |
|---|---|---|
| Lys 231 | Gln 231 | engineered mutation |
| Arg 462 | Lys 462 | engineered mutation |
| Thr 473 | Ala 473 | engineered mutation |
| Ala 483 | Gly 483 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 96153.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 971.7 | |
| All* | Total formula weight | 97124.6 |
