1UK0
Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase with a novel inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Poly [ADP-ribose] polymerase-1 | polymer | 350 | 39196.9 | 2 | UniProt (P09874) Pfam (PF02877) Pfam (PF00644) In PDB | Homo sapiens (human) | poly(ADP-ribose) polymerase, PARP-1, ADPRT, NAD(+) ADP-ribosyltransferase-1, Poly[ADP-ribose] synthetase-1 |
| 2 | A, B | 2-{3-[4-(4-FLUOROPHENYL)-3,6-DIHYDRO-1(2H)-PYRIDINYL]PROPYL}-8-METHYL-4(3H)-QUINAZOLINONE | non-polymer | 377.5 | 2 | Chemie (FRM) | |||
| 3 | water | water | 18.0 | 253 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78393.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 754.9 | |
| All* | Total formula weight | 79148.6 |
