1Q4G

2.0 Angstrom Crystal Structure of Ovine Prostaglandin H2 Synthase-1, in complex with alpha-methyl-4-biphenylacetic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Prostaglandin G/H synthase 1	polymer	553	63724.1	2	GenBank (165844) Pfam (PF03098) UniProt (by SIFTS) (P05979) In PDB	Ovis aries (sheep)	Cyclooxygenase -1, COX-1, Prostaglandin-endoperoxide synthase 1, Prostaglandin H2 synthase 1, PGH synthase 1, PGHS-1, PHS 1
2	C, F	2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G07375KG)
3	D, G	beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	2	In PDB GlyTouCan (G40894EI)
4	E	alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G42831WZ)
5	H	beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G07860ZO)
6	A, B	octyl beta-D-glucopyranoside	non-polymer		292.4	8	Chemie (BOG)
7	A, B	2-(1,1'-BIPHENYL-4-YL)PROPANOIC ACID	non-polymer		226.3	2	Chemie (BFL)
8	A, B	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
9	A, B	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
10		water	water		18.0	654	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	127448.3
Branched	Number of molecules	6
	Total formula weight	4167.8
Non-Polymers*	Number of molecules	17
	Total formula weight	4484.9
All*	Total formula weight	136101.0

*Water molecules are not included.