1KZI
Crystal Structure of EcTS/dUMP/THF Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Thymidylate synthase | polymer | 264 | 30559.7 | 2 | UniProt (P0A884) Pfam (PF00303) In PDB | Escherichia coli | TS, TSase |
| 2 | A | CARBONATE ION | non-polymer | 60.0 | 3 | Chemie (CO3) | |||
| 3 | A, B | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 2 | Chemie (UMP) | |||
| 4 | A, B | (6S)-5,6,7,8-TETRAHYDROFOLATE | non-polymer | 445.4 | 2 | Chemie (THG) | |||
| 5 | A | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL | non-polymer | 154.3 | 1 | Chemie (DTU) | |||
| 6 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | B | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 1 | Chemie (DTT) | |||
| 8 | water | water | 18.0 | 361 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 264 (UniProt: P0A884)
| PDB | External Database | Details |
|---|---|---|
| Cxm 1 | Met 1 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61119.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2087.8 | |
| All* | Total formula weight | 63207.2 |
