1I3R
CRYSTAL STRUCTURE OF A MUTANT IEK CLASS II MHC MOLECULE
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G | H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, E-K ALPHA CHAIN | polymer | 192 | 22359.1 | 4 | UniProt (P04224) Pfam (PF00993) Pfam (PF07654) In PDB | Mus musculus (house mouse) | |
2 | B, D, F, H | FUSION PROTEIN CONSISTING OF MHC E-BETA-K PRECURSOR, GLYCINE RICH LINKER, AND HEMOGLOBIN BETA-2 CHAIN | polymer | 228 | 25892.8 | 4 | UniProt (P02089) GenBank (199396) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P04230) In PDB | Mus musculus (house mouse) | |
3 | I, J, K, L | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
4 | A, B, C, D, E... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
5 | water | water | 18.0 | 319 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 1 - 192 (UniProt: P04224)
B, D, F, H: 1 - 13 (UniProt: P02089)
B, D, F, H: 29 - 224 (GenBank: 199396)
PDB | External Database | Details |
---|---|---|
Gln 11 | Glu 36 | engineered mutation |
Asn 66 | Asp 91 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Arg -3 | - | cloning artifact |
Asp -2 | - | cloning artifact |
Ser -1 | - | cloning artifact |
Arg 0 | - | cloning artifact |
Gly 14 | - | linker |
Gly 15 | - | linker |
Gly 16 | - | linker |
Gly 17 | - | linker |
Ser 18 | - | linker |
Leu 19 | - | linker |
Val 20 | - | linker |
Gly 21 | - | linker |
Gly 22 | - | linker |
Gly 23 | - | linker |
Ser 24 | - | linker |
Gly 25 | - | linker |
Gly 26 | - | linker |
Gly 27 | - | linker |
Gly 28 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 193007.7 | |
Branched | Number of molecules | 4 |
Total formula weight | 1697.6 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1769.7 | |
All* | Total formula weight | 196474.9 |