1I3R

CRYSTAL STRUCTURE OF A MUTANT IEK CLASS II MHC MOLECULE

Summary for 1I3R

• Entry DOI: 10.2210/pdb1i3r/pdb
• Related: 1IEA 1IEB
• Descriptor: H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, E-K ALPHA CHAIN, FUSION PROTEIN CONSISTING OF MHC E-BETA-K PRECURSOR, GLYCINE RICH LINKER, AND HEMOGLOBIN BETA-2 CHAIN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: mhc classii, immune system
• Biological source: Mus musculus (house mouse); More
• Cellular location: Membrane ; Single-pass type I membrane protein : P04224
• Total number of polymer chains: 8
• Total formula weight: 196474.92

Authors

Kappler, J.W.,Wilson, N. (deposition date: 2001-02-15, release date: 2001-06-20, Last modification date: 2021-10-27)

• Primary citation: Wilson, N.,Fremont, D.,Marrack, P.,Kappler, J.; Mutations changing the kinetics of class II MHC peptide exchange.; Immunity, 14:513-522, 2001; PubMed: 11371354; DOI: 10.1016/S1074-7613(01)00140-6

Experimental method

X-RAY DIFFRACTION (2.4 Å)