1E2J
The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | THYMIDINE KINASE | polymer | 331 | 35765.1 | 2 | UniProt (P03176) Pfam (PF00693) UniProt (by SIFTS) (P0DTH5) In PDB | HERPES SIMPLEX VIRUS (TYPE 1/STRAIN 17) | |
| 2 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | A, B | THYMIDINE | non-polymer | 242.2 | 2 | Chemie (THM) | |||
| 4 | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A, B: 46 - 376 (UniProt: P03176)
| PDB | External Database | Details |
|---|---|---|
| Asn 125 | Gln 125 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71530.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 676.6 | |
| All* | Total formula weight | 72206.7 |
