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2V2T
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BU of 2v2t by Molmil
X-ray structure of a NF-kB p50-RelB-DNA complex
Descriptor: 5'-D(*CP*GP*GP*GP*AP*AP*TP*TP*CP*CP*CP)-3', NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT, TRANSCRIPTION FACTOR RELB
Authors:Moorthy, A.K, Huang, D.B, Wang, V.Y, Vu, D, Ghosh, G.
Deposit date:2007-06-07
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:X-Ray Structure of a NF-kappaB p50/Relb/DNA Complex Reveals Assembly of Multiple Dimers on Tandem kappaB Sites.
J.Mol.Biol., 373, 2007
3BPQ
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BU of 3bpq by Molmil
Crystal Structure of RelB-RelE antitoxin-toxin complex from Methanococcus jannaschii
Descriptor: Antitoxin RelB3, Toxin RelE3
Authors:Francuski, D, Saenger, W.
Deposit date:2007-12-19
Release date:2008-12-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the antitoxin-toxin protein complex RelB-RelE from Methanococcus jannaschii
J.Mol.Biol., 393, 2009
4JGM
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BU of 4jgm by Molmil
Crystal structure of RelB double mutants: Y300F/I335V
Descriptor: Transcription factor RelB
Authors:Huang, D.B, Vu, D, Ghosh, G.
Deposit date:2013-03-01
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:A structural basis for selective dimerization by NF-kappa B RelB.
J.Mol.Biol., 425, 2013
2K29
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BU of 2k29 by Molmil
Structure of the DBD domain of E. coli antitoxin RelB
Descriptor: Antitoxin RelB
Authors:Li, G, Zhang, Y, Inouye, M, Ikura, M.
Deposit date:2008-03-28
Release date:2008-04-22
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structural mechanism of transcriptional autorepression of the Escherichia coli RelB/RelE antitoxin/toxin module.
J.Mol.Biol., 380, 2008
2KC8
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BU of 2kc8 by Molmil
Structure of E. coli toxin RelE (R81A/R83A) mutant in complex with antitoxin RelBc (K47-L79) peptide
Descriptor: Antitoxin RelB, Toxin relE
Authors:Li, G, Zhang, Y, Inouye, M, Ikura, M.
Deposit date:2008-12-17
Release date:2009-03-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Inhibitory mechanism of Escherichia coli RelE-RelB toxin-antitoxin module involves a helix displacement near an mRNA interferase active site.
J.Biol.Chem., 284, 2009
4FXE
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BU of 4fxe by Molmil
Crystal structure of the intact E. coli RelBE toxin-antitoxin complex
Descriptor: Antitoxin RelB, SULFATE ION, mRNA interferase RelE
Authors:Brodersen, D.E, Boggild, A, Sofos, N.
Deposit date:2012-07-03
Release date:2012-08-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7503 Å)
Cite:The crystal structure of the intact E. coli RelBE toxin-antitoxin complex provides the structural basis for conditional cooperativity.
Structure, 20, 2012
1ZKA
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BU of 1zka by Molmil
NF-kB RelB forms an intertwined homodimer, Y300S mutant
Descriptor: Transcription factor RelB
Authors:Huang, D.B, Vu, D, Ghosh, G.
Deposit date:2005-05-02
Release date:2005-05-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:NF-kappaB RelB forms an intertwined homodimer.
Structure, 13, 2005
1ZK9
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BU of 1zk9 by Molmil
NF-kB RelB forms an intertwined homodimer
Descriptor: Transcription factor RelB
Authors:Huang, D.B, Vu, D, Ghosh, G.
Deposit date:2005-05-02
Release date:2005-05-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:NF-kappaB RelB Forms an Intertwined Homodimer.
Structure, 13, 2005
3JV6
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BU of 3jv6 by Molmil
Crystal structure of the dimerization domains p52 and RelB
Descriptor: Nuclear factor NF-kappa-B p100 subunit, SULFATE ION, Transcription factor RelB
Authors:Vu, D, Huang, D.B, Ghosh, G.
Deposit date:2009-09-15
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:A structural basis for selective dimerization by NF-kappa B RelB.
J.Mol.Biol., 425, 2013
3JV4
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BU of 3jv4 by Molmil
Crystal structure of the dimerization domains p50 and RelB
Descriptor: Nuclear factor NF-kappa-B p105 subunit, Transcription factor RelB
Authors:Vu, D, Huang, D.B, Ghosh, G.
Deposit date:2009-09-15
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:A structural basis for selective dimerization by NF-kappa B RelB.
J.Mol.Biol., 425, 2013
3JSS
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BU of 3jss by Molmil
Crystal structure of a mutant RelB dimerization domain
Descriptor: Transcription factor RelB
Authors:Vu, D, Huang, D.B, Ghosh, G.
Deposit date:2009-09-10
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A structural basis for selective dimerization by NF-kappa B RelB.
J.Mol.Biol., 425, 2013
4JHB
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BU of 4jhb by Molmil
Crystal structure of RelB double mutants: Y300F/I335F
Descriptor: Transcription factor RelB
Authors:Huang, D.B, Vu, D, Ghosh, G.
Deposit date:2013-03-04
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Crystal structure of RelB double mutants: Y300F/I335F
TO BE PUBLISHED
3JUZ
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BU of 3juz by Molmil
Crystal structure of a mutant of RelB dimerization domain(M5)
Descriptor: Transcription factor RelB
Authors:Vu, D, Huang, D.B, Ghosh, G.
Deposit date:2009-09-15
Release date:2010-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Instability of the RelB dimerization domain is functionally important
To be Published
3JV0
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BU of 3jv0 by Molmil
Crystal structure of a mutant of RelB dimerization domain(M6)
Descriptor: Transcription factor RelB
Authors:Vu, D, Huang, D.B, Ghosh, G.
Deposit date:2009-09-15
Release date:2010-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Instability of the RelB dimerization domain is functionally importent
To be Published
7CNN
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BU of 7cnn by Molmil
vinorelbine in complex with tubulin
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Wang, Y.X, Wu, C.Y.
Deposit date:2020-08-02
Release date:2021-08-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The high-resolution X-ray structure of vinca-domain inhibitors of microtubules provides a rational approach for drug design.
Febs Lett., 595, 2021
1WMI
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BU of 1wmi by Molmil
Crystal structure of archaeal RelE-RelB complex from Pyrococcus horikoshii OT3
Descriptor: hypothetical protein PHS013, hypothetical protein PHS014
Authors:Takagi, H, Kakuta, Y, Kamachi, R, Yao, M, Tanaka, I, Kimura, M.
Deposit date:2004-07-09
Release date:2005-03-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of archaeal toxin-antitoxin RelE-RelB complex with implications for toxin activity and antitoxin effects
Nat.Struct.Mol.Biol., 12, 2005
3OEI
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BU of 3oei by Molmil
Crystal structure of Mycobacterium tuberculosis RelJK (Rv3357-Rv3358-RelBE3)
Descriptor: CITRATE ANION, RelJ (Antitoxin Rv3357), RelK (Toxin Rv3358)
Authors:Miallau, L, Cascio, D, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
Deposit date:2010-08-12
Release date:2011-03-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.145 Å)
Cite:Comparative proteomics identifies the cell-associated lethality of M. tuberculosis RelBE-like toxin-antitoxin complexes.
Structure, 21, 2013
3G5O
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BU of 3g5o by Molmil
The crystal structure of the toxin-antitoxin complex RelBE2 (Rv2865-2866) from Mycobacterium tuberculosis
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Miallau, L, Cascio, D, Eisenberg, D, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2009-02-05
Release date:2009-04-14
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Comparative proteomics identifies the cell-associated lethality of M. tuberculosis RelBE-like toxin-antitoxin complexes.
Structure, 21, 2013
2ADF
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BU of 2adf by Molmil
Crystal Structure and Paratope Determination of 82D6A3, an Antithrombotic Antibody Directed Against the von Willebrand factor A3-Domain
Descriptor: 82D6A3 IgG, ACETIC ACID, GLYCEROL, ...
Authors:Staelens, S, Hadders, M.A, Vauterin, S, Platteau, C, Vanhoorelbeke, K, Huizinga, E.G, Deckmyn, H.
Deposit date:2005-07-20
Release date:2005-12-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Paratope determination of the antithrombotic antibody 82D6A3 based on the crystal structure of its complex with the von Willebrand factor A3-domain
J.Biol.Chem., 281, 2006
8G8R
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BU of 8g8r by Molmil
RelB NLS in complex with Importin alpha 2
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Importin subunit alpha-1, Transcription factor RelB
Authors:Tsimbslyuk, S, Stewart, M, Forwood, J.K.
Deposit date:2023-02-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:monopartite p52 NLS in complex with Importin alpha 2
To Be Published
2KC9
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BU of 2kc9 by Molmil
Structure of E. coli toxin RelE (R81A/R83A) mutant in the free state
Descriptor: Toxin relE
Authors:Li, G, Zhang, Y, Inouye, M, Ikura, M.
Deposit date:2008-12-17
Release date:2009-03-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Inhibitory mechanism of Escherichia coli RelE-RelB toxin-antitoxin module involves a helix displacement near an mRNA interferase active site.
J.Biol.Chem., 284, 2009
4FXH
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BU of 4fxh by Molmil
Crystal structure of the isolated E. coli RelE toxin, P212121 form
Descriptor: SULFATE ION, mRNA interferase RelE
Authors:Brodersen, D.E, Boggild, A, Sofos, N.
Deposit date:2012-07-03
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of the intact E. coli RelBE toxin-antitoxin complex provides the structural basis for conditional cooperativity.
Structure, 20, 2012
4FXI
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BU of 4fxi by Molmil
Crystal structure of the isolated E. coli RelE toxin, P21 form
Descriptor: SULFATE ION, mRNA interferase RelE
Authors:Brodersen, D.E, Boggild, A, Sofos, N.
Deposit date:2012-07-03
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8003 Å)
Cite:The crystal structure of the intact E. coli RelBE toxin-antitoxin complex provides the structural basis for conditional cooperativity.
Structure, 20, 2012
3DO7
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BU of 3do7 by Molmil
X-ray structure of a NF-kB p52/RelB/DNA complex
Descriptor: 5'-D(*DCP*DGP*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DCP*DC)-3', Avian reticuloendotheliosis viral (V-rel) oncogene related B, Nuclear factor NF-kappa-B p100 subunit
Authors:Fusco, A, Huang, D.B, Miller, D, Vu, D, Ghosh, G.
Deposit date:2008-07-03
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:NF-kapppaB p52:RelB heterodimer uses different binding modes to recognize different kappaB DNA
TO BE PUBLISHED
2PX4
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BU of 2px4 by Molmil
Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAH (Monoclinic form 2)
Descriptor: CHLORIDE ION, GLYCEROL, Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], ...
Authors:Assenberg, R, Ren, J, Verma, A, Walter, T.S, Alderton, D, Hurrelbrink, R.J, Fuller, S.D, Owens, R.J, Stuart, D.I, Grimes, J.M, Oxford Protein Production Facility (OPPF)
Deposit date:2007-05-14
Release date:2007-05-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007

 

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