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1CID
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1cid
CRYSTAL STRUCTURE OF DOMAINS 3 & 4 OF RAT CD4 AND THEIR RELATIONSHIP TO THE NH2-TERMINAL DOMAINS
Descriptor:CD4 (DOMAINS 3 AND 4)
Authors:Brady, R.L., Dodson, E.J., Lange, G.
Deposit date:1993-01-28
Release date:1993-07-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of domains 3 and 4 of rat CD4: relation to the NH2-terminal domains.
Science, 260, 1993
1G9M
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1g9m
HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, CD4, ANTIBODY 17B-LIGHT AND HEAVY CHAIN COMPLEX
Authors:Kwong, P.D., Wyatt, R., Majeed, S., Robinson, J., Sweet, R.W., Sodroski, J., Hendrickson, W.A.
Deposit date:2000-11-24
Release date:2000-12-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
1G9N
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1g9n
HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, CD4, ANTIBODY 17B-LIGHT AND HEAVY CHAIN COMPLEX
Authors:Kwong, P.D., Wyatt, R., Majeed, S., Robinson, J., Sweet, R.W., Sodroski, J., Hendrickson, W.A.
Deposit date:2000-11-25
Release date:2000-12-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
1GC1
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1gc1
HIV-1 GP120 CORE COMPLEXED WITH CD4 AND A NEUTRALIZING HUMAN ANTIBODY
Descriptor:ENVELOPE PROTEIN GP120, CD4, ANTIBODY 17B
Authors:Kwong, P.D., Wyatt, R., Robinson, J., Sweet, R.W., Sodroski, J., Hendrickson, W.A.
Deposit date:1998-06-15
Release date:1998-07-08
Modification date:2013-09-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody.
Nature, 393, 1998
1RZJ
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1rzj
HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEINS GP120 AND CD4/ANTIBODY 17B-LIGHT AND HEAVY CHAINS COMPLEX
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
1RZK
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1rzk
HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEINS GP120 AND CD4/ANTIBODY 17B-LIGHT AND HEAVY CHAINS COMPLEX
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
1WIO
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1wio
STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, TETRAGONAL CRYSTAL FORM
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Kwong, P.D., Hendrickson, W.A.
Deposit date:1996-12-18
Release date:1997-07-07
Modification date:2014-04-16
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Dimeric association and segmental variability in the structure of human CD4.
Nature, 387, 1997
1WIP
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1wip
STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, MONOCLINIC CRYSTAL FORM
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Kwong, P.D., Hendrickson, W.A.
Deposit date:1996-12-18
Release date:1997-07-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (4 Å)
Cite:Dimeric association and segmental variability in the structure of human CD4.
Nature, 387, 1997
1WIQ
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1wiq
STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, TRIGONAL CRYSTAL FORM
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Kwong, P.D., Hendrickson, W.A.
Deposit date:1996-12-18
Release date:1997-07-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (5 Å)
Cite:Dimeric association and segmental variability in the structure of human CD4.
Nature, 387, 1997
2B4C
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2b4c
CRYSTAL STRUCTURE OF HIV-1 JR-FL GP120 CORE PROTEIN CONTAINING THE THIRD VARIABLE REGION (V3) COMPLEXED WITH CD4 AND THE X5 ANTIBODY
Descriptor:envelope glycoprotein, T-cell surface glycoprotein CD4, anti-HIV-1 gp120 immunoglobulin X5 light chain, anti-HIV-1 gp120 immunoglobulin X5 heavy chain
Authors:Huang, C., Tang, M., Zhang, M.Y., Majeed, S., Montabana, E., Stanfield, R.L., Dimitrov, D.S., Korber, B., Sodroski, J., Wilson, I.A., Wyatt, R., Kwong, P.D.
Deposit date:2005-09-23
Release date:2005-11-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of a V3-containing HIV-1 gp120 core.
Science, 310, 2005
2NXY
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2nxy
HIV-1 GP120 ENVELOPE GLYCOPROTEIN(S334A) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120 , T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN, ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NXZ
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2nxz
HIV-1 GP120 ENVELOPE GLYCOPROTEIN (T257S, S334A, S375W) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120 , T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN, ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY0
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2ny0
HIV-1 GP120 ENVELOPE GLYCOPROTEIN (M95W, W96C, T257S, V275C, S334A, S375W, A433M) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120 , T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN, ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY1
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2ny1
HIV-1 GP120 ENVELOPE GLYCOPROTEIN (I109C, T257S, S334A, S375W, Q428C) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120 , T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN , ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X, Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY2
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2ny2
HIV-1 GP120 ENVELOPE GLYCOPROTEIN (T123C, T257S, S334A, S375W, G431C) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN, ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY3
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2ny3
HIV-1 GP120 ENVELOPE GLYCOPROTEIN (K231C, T257S, E267C, S334A, S375W) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN, ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY4
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2ny4
HIV-1 GP120 ENVELOPE GLYCOPROTEIN (K231C, T257S, E268C, S334A, S375W) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120 , T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN , ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY5
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2ny5
HIV-1 GP120 ENVELOPE GLYCOPROTEIN (M95W, W96C, I109C, T257S, V275C, S334A, S375W, Q428C, A433M) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120 , T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN , ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY6
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2ny6
HIV-1 GP120 ENVELOPE GLYCOPROTEIN (M95W, W96C, I109C, T123C, T257S, V275C,S334A, S375W, Q428C, G431C) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120 , T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN , ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2QAD
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2qad
STRUCTURE OF TYROSINE-SULFATED 412D ANTIBODY COMPLEXED WITH HIV-1 YU2 GP120 AND CD4
Descriptor:Envelope glycoprotein gp160, T-cell surface glycoprotein CD4, anti-HIV-1 antibody 412d light chain, anti-HIV-1 antibody 412d heavy chain
Authors:Huang, C.-C., Tang, M., Robinson, J., Wyatt, R., Kwong, P.D.
Deposit date:2007-06-14
Release date:2007-09-25
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4
Science, 317, 2007
3CD4
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3cd4
REFINEMENT AND ANALYSIS OF THE FIRST TWO DOMAINS OF HUMAN CD4
Descriptor:CD4 (N-TERMINAL FRAGMENT CONSISTING OF RESIDUES 1-182)
Authors:Garrett, T.P.J., Wang, J., Yan, Y., Harrison, S.C.
Deposit date:1992-07-30
Release date:1993-10-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refinement and analysis of the structure of the first two domains of human CD4
J.Mol.Biol., 234, 1993
3JWD
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3jwd
STRUCTURE OF HIV-1 GP120 WITH GP41-INTERACTIVE REGION: LAYERED ARCHITECTURE AND BASIS OF CONFORMATIONAL MOBILITY
Descriptor:HIV-1 GP120 ENVELOPE GLYCOPROTEIN, T-cell surface glycoprotein CD4, FAB 48D LIGHT CHAIN, FAB 48D HEAVY CHAIN
Authors:Pancera, M., Majeed, S., Ban, Y.A., Chen, L., Huang, C.C., Kong, L., Kwon, Y.D., Stuckey, J., Zhou, T., Robinson, J.E., Schief, W.R., Sodroski, J., Wyatt, R., Kwong, P.D.
Deposit date:2009-09-18
Release date:2009-12-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility.
Proc.Natl.Acad.Sci.USA, 107, 2010
3JWO
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3jwo
STRUCTURE OF HIV-1 GP120 WITH GP41-INTERACTIVE REGION: LAYERED ARCHITECTURE AND BASIS OF CONFORMATIONAL MOBILITY
Descriptor:HIV-1 GP120 ENVELOPE GLYCOPROTEIN , T-cell surface glycoprotein CD4, FAB 48D LIGHT CHAIN, FAB 48D Heavy CHAIN
Authors:Pancera, M., Majeed, S., Huang, C.C., Kwon, Y.D., Zhou, T., Robinson, J.E., Sodroski, J., Wyatt, R., Kwong, P.D.
Deposit date:2009-09-18
Release date:2009-12-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LQA
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3lqa
CRYSTAL STRUCTURE OF CLADE C GP120 IN COMPLEX WITH SCD4 AND 21C FAB
Descriptor:T-cell surface glycoprotein CD4, Envelope glycoprotein gp160, Heavy chain of anti HIV Fab from human 21c antibody, Light chain of anti HIV Fab from human 21c antibody
Authors:Diskin, R., Marcovecchio, P.M., Bjorkman, P.J.
Deposit date:2010-02-08
Release date:2010-04-07
Modification date:2010-05-26
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity.
Nat.Struct.Mol.Biol., 17, 2010
3O2D
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3o2d
CRYSTAL STRUCTURE OF HIV-1 PRIMARY RECEPTOR CD4 IN COMPLEX WITH A POTENT ANTIVIRAL ANTIBODY
Descriptor:ibalizumab light chain, ibalizumab heavy chain, T-cell surface glycoprotein CD4
Authors:Freeman, M.M., Seaman, M.S., Rits-Volloch, S., Hong, X., Ho, D.D., Chen, B.
Deposit date:2010-07-22
Release date:2010-12-22
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystal Structure of HIV-1 Primary Receptor CD4 in Complex with a Potent Antiviral Antibody.
Structure, 18, 2010
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