3T0E

Crystal structure of a complete ternary complex of T cell receptor, peptide-MHC and CD4

Summary for 3T0E

• Entry DOI: 10.2210/pdb3t0e/pdb
• Related: 3O6F
• Descriptor: HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-4 beta chain, T-cell receptor alpha chain, ... (5 entities in total)
• Functional Keywords: cd4, t cell receptor, tcr, hla class ii, mhc, autoimmunity, t cell activation, immunoglobulin fold, immune system, membrane
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane; Single-pass type I membrane protein: P01903 P13760 P01730
• Total number of polymer chains: 5
• Total formula weight: 138315.22

Authors

Yin, Y.,Mariuzza, R.A. (deposition date: 2011-07-20, release date: 2012-03-07, Last modification date: 2017-11-08)

• Primary citation: Yin, Y.,Wang, X.X.,Mariuzza, R.A.; Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4.; Proc.Natl.Acad.Sci.USA, 109:5405-5410, 2012; PubMed: 22431638; DOI: 10.1073/pnas.1118801109

Experimental method

X-RAY DIFFRACTION (4 Å)