4K3L
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E. COLI SLIDING CLAMP IN COMPLEX WITH ACLF DIPEPTIDE
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)
Authors:Yin, Z., Oakley, A.J.
Deposit date:2013-04-10
Release date:2013-05-01
Modification date:2014-01-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
4TR6
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CRYSTAL STRUCTURE OF DNA POLYMERASE SLIDING CLAMP FROM BACILLUS SUBTILIS
Descriptor:DNA polymerase sliding clamp from Bacillus subtilis
Authors:Burnouf, D., Olieric, V., Ennifar, E., Wolff, P.
Deposit date:2014-06-14
Release date:2014-09-10
Modification date:2014-11-19
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins.
J.Med.Chem., 57, 2014
4MJR
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E. COLI SLIDING CLAMP IN COMPLEX WITH (S)-CARPROFEN
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)
Authors:Yin, Z., Oakley, A.J.
Deposit date:2013-09-04
Release date:2013-09-18
Modification date:2014-06-04
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
Chem.Biol., 21, 2014
3D1G
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STRUCTURE OF A SMALL MOLECULE INHIBITOR BOUND TO A DNA SLIDING CLAMP
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)
Authors:Georgescu, R.E., Yurieva, O., Seung-Sup, K., Kuriyan, J., Kong, X-P., O'Donnell, M.
Deposit date:2008-05-05
Release date:2008-07-29
Modification date:2009-06-09
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1OK7
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A CONSERVED PROTEIN BINDING-SITE ON BACTERIAL SLIDING CLAMPS
Descriptor:DNA POLYMERASE III (E.C.2.7.7.7), DNA POLYMERASE IV (E.C.2.7.7.7)
Authors:Burnouf, D.Y., Olieric, V., Wagner, J., Fujii, S., Reinbolt, J., Fuchs, R.P.P., Dumas, P.
Deposit date:2003-07-18
Release date:2004-07-15
Modification date:2015-09-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural and Biochemical Analysis of Sliding Clamp/Ligand Interactions Suggest a Competition between Replicative and Translesion DNA Polymerases
J.Mol.Biol., 335, 2004
4N96
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E. COLI SLIDING CLAMP IN COMPLEX WITH 6-NITROINDAZOLE
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)
Authors:Yin, Z., Oakley, A.J.
Deposit date:2013-10-19
Release date:2013-11-06
Modification date:2014-04-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach.
J.Med.Chem., 57, 2014
4N98
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E. COLI SLIDING CLAMP IN COMPLEX WITH 4'-FLUOROBIPHENYL-4-CARBOXYLIC ACID
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)
Authors:Yin, Z., Oakley, A.J.
Deposit date:2013-10-19
Release date:2013-11-06
Modification date:2014-04-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach.
J.Med.Chem., 57, 2014
4MJQ
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E. COLI SLIDING CLAMP IN COMPLEX WITH BROMFENAC
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)
Authors:Yin, Z., Oakley, A.J.
Deposit date:2013-09-04
Release date:2013-09-18
Modification date:2014-06-04
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
Chem.Biol., 21, 2014
4N94
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E. COLI SLIDING CLAMP IN COMPLEX WITH 3,4-DIFLUOROBENZAMIDE
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)
Authors:Yin, Z., Oakley, A.J.
Deposit date:2013-10-19
Release date:2013-11-06
Modification date:2014-04-09
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach.
J.Med.Chem., 57, 2014
4K3S
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E. COLI SLIDING CLAMP IN P1 CRYSTAL SPACE GROUP
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)
Authors:Yin, Z., Oakley, A.J.
Deposit date:2013-04-11
Release date:2013-05-01
Modification date:2014-01-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
3F1V
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E. COLI BETA SLIDING CLAMP, 148-153 ALA MUTANT
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)
Authors:Cody, V.
Deposit date:2008-10-28
Release date:2009-09-01
Modification date:2011-03-09
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Sliding clamp-DNA interactions are required for viability and contribute to DNA polymerase management in Escherichia coli.
J.Mol.Biol., 387, 2009
4N95
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E. COLI SLIDING CLAMP IN COMPLEX WITH 5-CHLOROINDOLINE-2,3-DIONE
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)
Authors:Yin, Z., Oakley, A.J.
Deposit date:2013-10-19
Release date:2013-11-06
Modification date:2014-04-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach.
J.Med.Chem., 57, 2014
1MMI
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E. COLI DNA POLYMERASE BETA SUBUNIT
Descriptor:DNA polymerase III, beta chain (E.C.2.7.7.7)
Authors:Oakley, A.J., Prosselkov, P., Wijffels, G., Beck, J.L., Wilce, M.C.J., Dixon, N.E.
Deposit date:2002-09-04
Release date:2003-09-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.848 Å)
Cite:Flexibility revealed by the 1.85 A crystal structure of the beta sliding-clamp subunit of Escherichia coli DNA polymerase III.
Acta Crystallogr.,Sect.D, 59, 2003
4K3K
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E. COLI SLIDING CLAMP IN COMPLEX WITH (S)-2-(4-METHYLPENTANAMIDO)-3-PHENYLPROPANOIC ACID
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)
Authors:Yin, Z., Oakley, A.J.
Deposit date:2013-04-10
Release date:2013-05-01
Modification date:2014-01-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
4K3M
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E.COLI SLIDING CLAMP IN COMPLEX WITH ACALDLF PEPTIDE
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7), ALDLF
Authors:Yin, Z., Oakley, A.J.
Deposit date:2013-04-11
Release date:2013-05-01
Modification date:2014-01-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
4K3Q
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E. COLI SLIDING CLAMP IN COMPLEX WITH ACQLDAF
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7), (ACE)QLDAF
Authors:Yin, Z., Oakley, A.J.
Deposit date:2013-04-11
Release date:2013-05-01
Modification date:2014-01-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
4MJP
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E. COLI SLIDING CLAMP IN COMPLEX WITH (R)-VEDAPROFEN
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)
Authors:Yin, Z., Oakley, A.J.
Deposit date:2013-09-04
Release date:2013-09-18
Modification date:2014-06-04
Method:X-RAY DIFFRACTION (1.855 Å)
Cite:DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
Chem.Biol., 21, 2014
4K3R
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E. COLI SLIDING CLAMP IN COMPLEX WITH ACQLDLA
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7), (ACE)QLDLA
Authors:Yin, Z., Oakley, A.J.
Deposit date:2013-04-11
Release date:2013-05-01
Modification date:2014-01-15
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
1UNN
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COMPLEX OF BETA-CLAMP PROCESSIVITY FACTOR AND LITTLE FINGER DOMAIN OF POLIV
Descriptor:DNA POLYMERASE III BETA SUBUNIT (E.C.2.7.7.7), DNA POLYMERASE IV (E.C.2.7.7.7)
Authors:Bunting, K.A., Roe, S.M., Pearl, L.H.
Deposit date:2003-09-11
Release date:2003-11-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Recruitment of Translesion DNA Polymerase Pol Iv/Dinb to the Beta-Clamp
Embo J., 22, 2003
2XUR
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THE G157C MUTATION IN THE ESCHERICHIA COLI SLIDING CLAMP SPECIFICALLY AFFECTS INITIATION OF REPLICATION
Descriptor:DNA POLYMERASE III SUBUNIT BETA (E.C.2.7.7.7)
Authors:Johnsen, L., Morigen, Dalhus, B., Bjoras, M., Flaatten, I., Waldminghaus, T., Skarstad, K.
Deposit date:2010-10-20
Release date:2011-02-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The G157C Mutation in the Escherichia Coli Sliding Clamp Specifically Affects Initiation of Replication.
Mol.Microbiol., 79, 2011
3D1E
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CRYSTAL STRUCTURE OF E. COLI SLIDING CLAMP (BETA) BOUND TO A POLYMERASE II PEPTIDE
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)/14-mer from polymerase II C-terminal
Authors:Georgescu, R.E., Yurieva, O., Seung-Sup, K., Kuriyan, J., Kong, X-P., O'Donnell, M.
Deposit date:2008-05-05
Release date:2008-07-29
Modification date:2009-06-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3QSB
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STRUCTURE OF E. COLI POLIIIBETA WITH (Z)-5-(1-((4'-FLUOROBIPHENYL-4-YL)METHOXYIMINO)BUTYL)-2,2-DIMETHYL-4,6-DIOXOCYCLOHEXANECARBONITRILE
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)
Authors:Wijffels, G., Johnson, W.M., Oakley, A.J., Turner, K., Epa, V.C., Briscoe, S.J., Polley, M., Liepa, A.J., Hofmann, A., Buchardt, J., Christensen, C., Prosselkov, P., Dalrymple, B.P., Alewood, P.F., Jennings, P.A., Dixon, N.E., Winkler, D.A.
Deposit date:2011-02-20
Release date:2011-06-08
Modification date:2014-03-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Binding inhibitors of the bacterial sliding clamp by design
J.Med.Chem., 54, 2011
4N9A
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E. COLI SLIDING CLAMP IN COMPLEX WITH (R)-6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-1-CARBOXYLIC ACID
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)
Authors:Yin, Z., Oakley, A.J.
Deposit date:2013-10-19
Release date:2013-11-06
Modification date:2014-04-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach.
J.Med.Chem., 57, 2014
3BEP
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STRUCTURE OF A SLIDING CLAMP ON DNA
Descriptor:DNA polymerase III subunit beta (E.C.2.7.7.7)/DNA
Authors:Georgescu, R.E., Kim, S.S., Yurieva, O., Kuriyan, J., Kong, X.-P., O'Donnell, M.
Deposit date:2007-11-19
Release date:2008-01-29
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure of a sliding clamp on DNA
Cell(Cambridge,Mass.), 132, 2008
5AGV
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THE SLIDING CLAMP OF MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH A NATURAL PRODUCT.
Descriptor:DNA POLYMERASE III SUBUNIT BETA (E.C.2.7.7.7), CYCLOHEXYL GRISELIMYCIN
Authors:Lukat, P., Kling, A., Heinz, D.W., Mueller, R.
Deposit date:2015-02-03
Release date:2015-06-03
Modification date:2015-06-24
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
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