8PAY
Structure of the E.coli DNA polymerase sliding clamp with a covalently bound peptide 2.
Summary for 8PAY
Entry DOI | 10.2210/pdb8pay/pdb |
Descriptor | Beta sliding clamp, ACE-GLN-ALC-GLC-LEU-PHE, GLYCEROL, ... (5 entities in total) |
Functional Keywords | sliding clamp, covalent peptide, antibiotics, replication |
Biological source | Escherichia coli More |
Total number of polymer chains | 2 |
Total formula weight | 42806.97 |
Authors | Compain, G.,Monsarrat, C.,Blagojevic, J.,Brillet, K.,Dumas, P.,Hammann, P.,Kuhn, L.,Martiel, I.,Engilberge, S.,Olieric, V.,Wolff, P.,Burnouf, D.,wagner, J.,Guichard, G. (deposition date: 2023-06-08, release date: 2024-03-13) |
Primary citation | Compain, G.,Monsarrat, C.,Blagojevic, J.,Brillet, K.,Dumas, P.,Hammann, P.,Kuhn, L.,Martiel, I.,Engilberge, S.,Olieric, V.,Wolff, P.,Burnouf, D.Y.,Wagner, J.,Guichard, G. Peptide-Based Covalent Inhibitors Bearing Mild Electrophiles to Target a Conserved His Residue of the Bacterial Sliding Clamp. Jacs Au, 4:432-440, 2024 Cited by PubMed: 38425897DOI: 10.1021/jacsau.3c00572 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.21 Å) |
Structure validation
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