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2O8B
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2o8b
HUMAN MUTSALPHA (MSH2/MSH6) BOUND TO ADP AND A G T MISPAIR
Descriptor:DNA mismatch repair protein Msh2/ DNA mismatch repair protein MSH6/DNA Complex
Authors:Warren, J.J., Pohlhaus, T.J., Changela, A., Modrich, P.L., Beese, L.S.
Deposit date:2006-12-12
Release date:2007-06-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of the Human MutSalpha DNA Lesion Recognition Complex.
Mol.Cell, 26, 2007
2O8C
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2o8c
HUMAN MUTSALPHA (MSH2/MSH6) BOUND TO ADP AND AN O6-METHYL-GUANINE T MISPAIR
Descriptor:DNA mismatch repair protein Msh2/DNA mismatch repair protein Msh6/DNA Complex
Authors:Warren, J.J., Pohlhaus, T.J., Changela, A., Modrich, P.L., Beese, L.S.
Deposit date:2006-12-12
Release date:2007-06-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.37 Å)
Cite:Structure of the Human MutSalpha DNA Lesion Recognition Complex.
Mol.Cell, 26, 2007
2O8D
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2o8d
HUMAN MUTSALPHA (MSH2/MSH6) BOUND TO ADP AND A G DU MISPAIR
Descriptor:DNA mismatch repair protein Msh2/DNA mismatch repair protein MSH6/DNA Complex
Authors:Warren, J.J., Pohlhaus, T.J., Changela, A., Modrich, P.L., Beese, L.S.
Deposit date:2006-12-12
Release date:2007-06-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the Human MutSalpha DNA Lesion Recognition Complex.
Mol.Cell, 26, 2007
2O8E
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2o8e
HUMAN MUTSALPHA (MSH2/MSH6) BOUND TO A G T MISPAIR, WITH ADP BOUND TO MSH2 ONLY
Descriptor:DNA mismatch repair protein Msh2/DNA mismatch repair protein MSH6/DNA Complex
Authors:Warren, J.J., Pohlhaus, T.J., Changela, A., Modrich, P.L., Beese, L.S.
Deposit date:2006-12-12
Release date:2007-06-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the Human MutSalpha DNA Lesion Recognition Complex.
Mol.Cell, 26, 2007
2O8F
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2o8f
HUMAN MUTSALPHA (MSH2/MSH6) BOUND TO DNA WITH A SINGLE BASE T INSERT
Descriptor:DNA mismatch repair protein Msh2/DNA mismatch repair protein MSH6/DNA Complex
Authors:Warren, J.J., Pohlhaus, T.J., Changela, A., Modrich, P.L., Beese, L.S.
Deposit date:2006-12-12
Release date:2007-06-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure of the Human MutSalpha DNA Lesion Recognition Complex.
Mol.Cell, 26, 2007
3THW
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3thw
HUMAN MUTSBETA COMPLEXED WITH AN IDL OF 4 BASES (LOOP4) AND ADP
Descriptor:DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3/DNA complex
Authors:Yang, W.
Deposit date:2011-08-19
Release date:2011-12-21
Modification date:2013-06-26
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Mechanism of mismatch recognition revealed by human MutSbeta bound to unpaired DNA loops
Nat.Struct.Mol.Biol., 19, 2012
3THX
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3thx
HUMAN MUTSBETA COMPLEXED WITH AN IDL OF 3 BASES (LOOP3) AND ADP
Descriptor:DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3/DNA complex
Authors:Yang, W.
Deposit date:2011-08-19
Release date:2011-12-21
Modification date:2013-06-26
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanism of mismatch recognition revealed by human MutSbeta bound to unpaired DNA loops
Nat.Struct.Mol.Biol., 19, 2012
3THY
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3thy
HUMAN MUTSBETA COMPLEXED WITH AN IDL OF 2 BASES (LOOP2) AND ADP
Descriptor:DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3/DNA complex
Authors:Yang, W.
Deposit date:2011-08-19
Release date:2011-12-21
Modification date:2013-06-26
Method:X-RAY DIFFRACTION (2.894 Å)
Cite:Mechanism of mismatch repair revealed by human MutSbeta bound to unpaired DNA loops
Nat.Struct.Mol.Biol., 19, 2012
3THZ
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3thz
HUMAN MUTSBETA COMPLEXED WITH AN IDL OF 6 BASES (LOOP6) AND ADP
Descriptor:DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3/DNA complex
Authors:Yang, W.
Deposit date:2011-08-19
Release date:2011-12-21
Modification date:2013-06-26
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Mechanism of mismatch repair revealed by human MutS bound to unpaired DNA loops
Nat.Struct.Mol.Biol., 19, 2012
1E3M
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1e3m
THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH A G:T MISMATCH
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS
Authors:Lamers, M.H., Perrakis, A., Enzlin, J.H., Winterwerp, H.H.K., De Wind, N., Sixma, T.K.
Deposit date:2000-06-19
Release date:2000-11-01
Modification date:2014-02-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of DNA Mismatch Repair Protein Muts Binding to a G X T Mismatch
Nature, 407, 2000
1EWQ
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1ewq
CRYSTAL STRUCTURE TAQ MUTS COMPLEXED WITH A HETERODUPLEX DNA AT 2.2 A RESOLUTION
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS/DNA COMPLEX
Authors:Obmolova, G., Ban, C., Hsieh, P., Yang, W.
Deposit date:2000-04-26
Release date:2000-10-23
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA.
Nature, 407, 2000
1FW6
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1fw6
CRYSTAL STRUCTURE OF A TAQ MUTS-DNA-ADP TERNARY COMPLEX
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS/DNA COMPLEX
Authors:Junop, M.S., Obmolova, G., Rausch, K., Hsieh, P., Yang, W.
Deposit date:2000-09-21
Release date:2001-02-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair.
Mol.Cell, 7, 2001
1NG9
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1ng9
E.COLI MUTS R697A: AN ATPASE-ASYMMETRY MUTANT
Descriptor:DNA mismatch repair protein MutS/DNA Complex
Authors:Lamers, M.H., Winterwerp, H.H.K., Sixma, T.K.
Deposit date:2002-12-17
Release date:2003-02-11
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The alternating ATPase domains of MutS control DNA mismatch repair
Embo J., 22, 2003
1NNE
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1nne
CRYSTAL STRUCTURE OF THE MUTS-ADPBEF3-DNA COMPLEX
Descriptor:DNA Mismatch Repair protein MutS/DNA
Authors:Alani, E., Lee, J.Y., Schofield, M.J., Kijas, A.W., Hsieh, P., Yang, W.
Deposit date:2003-01-13
Release date:2003-05-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Crystal structure and biochemical analysis of the MutS-ADP-Beryllium Fluoride complex suggests a conserved mechanism for ATP interactions in mismatch repair
J.Biol.Chem., 278, 2003
1OH5
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1oh5
THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH A C:A MISMATCH
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS
Authors:Natrajan, G., Lamers, M.H., Enzlin, J.H., Winterwerp, H.H.K., Perrakis, A., Sixma, T.K.
Deposit date:2003-05-23
Release date:2003-08-08
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates
Nucleic Acids Res., 31, 2003
1OH6
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1oh6
THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH AN A:A MISMATCH
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS
Authors:Natrajan, G., Lamers, M.H., Enzlin, J.H., Winterwerp, H.H.K., Perrakis, A., Sixma, T.K.
Deposit date:2003-05-23
Release date:2003-08-08
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates
Nucleic Acids Res., 31, 2003
1OH7
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1oh7
THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH A G:G MISMATCH
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS
Authors:Natrajan, G., Lamers, M.H., Enzlin, J.H., Winterwerp, H.H.K., Perrakis, A., Sixma, T.K.
Deposit date:2003-05-23
Release date:2003-08-08
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates
Nucleic Acids Res., 31, 2003
1OH8
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1oh8
THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH AN UNPAIRED THYMIDINE
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS
Authors:Natrajan, G., Lamers, M.H., Enzlin, J.H., Winterwerp, H.H.K., Perrakis, A., Sixma, T.K.
Deposit date:2003-05-23
Release date:2003-08-08
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates
Nucleic Acids Res., 31, 2003
1W7A
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1w7a
ATP BOUND MUTS
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS
Authors:Lamers, M.H., Georgijevic, D., Lebbink, J., Winterwerp, H.H.K., Agianian, B., De Wind, N., Sixma, T.K.
Deposit date:2004-08-31
Release date:2004-09-10
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:ATP Increases the Affinity between Muts ATPase Domains: Implications for ATP Hydrolysis and Conformational Changes
J.Biol.Chem., 279, 2004
1WB9
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1wb9
CRYSTAL STRUCTURE OF E. COLI DNA MISMATCH REPAIR ENZYME MUTS, E38T MUTANT, IN COMPLEX WITH A G.T MISMATCH
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS
Authors:Natrajan, G., Georgijevic, D., Lebbink, J.H.G., Winterwerp, H.H.K., De Wind, N., Sixma, T.K.
Deposit date:2004-10-31
Release date:2006-01-18
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dual Role of Muts Glutamate 38 in DNA Mismatch Discrimination and in the Authorization of Repair.
Embo J., 25, 2006
1WBB
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1wbb
CRYSTAL STRUCTURE OF E. COLI DNA MISMATCH REPAIR ENZYME MUTS, E38A MUTANT, IN COMPLEX WITH A G.T MISMATCH
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS
Authors:Natrajan, G., Georgijevic, D., Lebbink, J.H.G., Winterwerp, H.H.K., De Wind, N., Sixma, T.K.
Deposit date:2004-10-31
Release date:2006-01-18
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dual Role of Muts Glutamate 38 in DNA Mismatch Discrimination and in the Authorization of Repair.
Embo J., 25, 2006
1WBD
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1wbd
CRYSTAL STRUCTURE OF E. COLI DNA MISMATCH REPAIR ENZYME MUTS, E38Q MUTANT, IN COMPLEX WITH A G.T MISMATCH
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS
Authors:Natrajan, G., Georgijevic, D., Lebbink, J.H.G., Winterwerp, H.H.K., De Wind, N., Sixma, T.K.
Deposit date:2004-10-31
Release date:2006-01-18
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Dual Role of Muts Glutamate 38 in DNA Mismatch Discrimination and in the Authorization of Repair.
Embo J., 25, 2006
2WTU
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2wtu
CRYSTAL STRUCTURE OF ESCHERICHIA COLI MUTS IN COMPLEX WITH A 16 BASEPAIR OLIGO CONTAINING AN A.A MISMATCH.
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS
Authors:Natrajan, G., Lebbink, J.H., Reumer, A., Fish, A., Winterwerp, H.H., Sixma, T.K.
Deposit date:2009-09-22
Release date:2010-02-09
Modification date:2010-04-28
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Magnesium Coordination Controls the Molecular Switch Function of DNA Mismatch Repair Protein Muts.
J.Biol.Chem., 285, 2010
3K0S
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3k0s
CRYSTAL STRUCTURE OF E.COLI DNA MISMATCH REPAIR PROTEIN MUTS, D693N MUTANT, IN COMPLEX WITH GT MISMATCHED DNA
Descriptor:DNA mismatch repair protein mutS
Authors:Reumer, G.A., Winterwerp, H.H.K., Sixma, T.K.
Deposit date:2009-09-25
Release date:2010-02-16
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Magnesium coordination controls the molecular switch function of DNA mismatch repair protein MutS.
J.Biol.Chem., 285, 2010
3ZLJ
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3zlj
CRYSTAL STRUCTURE OF FULL-LENGTH E.COLI DNA MISMATCH REPAIR PROTEIN MUTS D835R MUTANT IN COMPLEX WITH GT MISMATCHED DNA
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS
Authors:Groothuizen, F.S., Fish, A., Petoukhov, M.V., Reumer, A., Manelyte, L., Winterwerp, H.H.K., Marinus, M.G., Lebbink, J.H.G., Svergun, D.I., Friedhoff, P., Sixma, T.K.
Deposit date:2013-02-01
Release date:2013-07-17
Modification date:2013-10-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Using Stable Muts Dimers and Tetramers to Quantitatively Analyze DNA Mismatch Recognition and Sliding Clamp Formation.
Nucleic Acids Res., 41, 2013
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