3THW

Human MutSbeta complexed with an IDL of 4 bases (Loop4) and ADP

Summary for 3THW

• Entry DOI: 10.2210/pdb3thw/pdb
• Related: 3THX 3THY 3THZ
• Descriptor: DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, DNA Loop4 hairpin, ... (5 entities in total)
• Functional Keywords: abc family atpase, mismatch recognition, mismatched unpaired idl dna, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : P43246
• Total number of polymer chains: 3
• Total formula weight: 225906.22

Authors

Yang, W. (deposition date: 2011-08-19, release date: 2011-12-21, Last modification date: 2023-09-13)

• Primary citation: Gupta, S.,Gellert, M.,Yang, W.; Mechanism of mismatch recognition revealed by human MutSbeta bound to unpaired DNA loops; Nat.Struct.Mol.Biol., 19:72-78, 2012; PubMed: 22179786; DOI: 10.1038/nsmb.2175

Experimental method

X-RAY DIFFRACTION (3.09 Å)