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6ZBK
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BU of 6zbk by Molmil
Crystal structure of the human complex between RPAP3 and TRBP
Descriptor: RISC-loading complex subunit TARBP2, RNA polymerase II-associated protein 3
Authors:Charron, C, Abel, Y, Charpentier, B, Rederstorff, M.
Deposit date:2020-06-08
Release date:2021-06-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:The interaction between RPAP3 and TRBP reveals a possible involvement of the HSP90/R2TP chaperone complex in the regulation of miRNA activity.
Nucleic Acids Res., 50, 2022
5LYP
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BU of 5lyp by Molmil
Crystal structure of the Tpr Domain of Sgt2.
Descriptor: BORATE ION, Small glutamine-rich tetratricopeptide repeat-containing protein 2
Authors:Krysztofinska, E.M, Morgan, R.M.L, Thapaliya, A, Evans, N.J, Murray, J.W, Martinez-Lumbreras, S, Isaacson, R.L.
Deposit date:2016-09-28
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp.
Front Mol Biosci, 4, 2017
4GCO
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BU of 4gco by Molmil
Central domain of stress-induced protein-1 (STI-1) from C.elegans
Descriptor: Protein STI-1
Authors:Osipiuk, J, Bigelow, L, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2012-07-30
Release date:2012-08-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Central domain of stress-induced protein-1 (STI-1) from C.elegans
To be Published
3UPV
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BU of 3upv by Molmil
TPR2B-domain:pHsp70-complex of yeast Sti1
Descriptor: Heat shock protein SSA4, Heat shock protein STI1
Authors:Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H.
Deposit date:2011-11-18
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop.
Embo J., 31, 2012
6EOU
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BU of 6eou by Molmil
O-GlcNAc transferase TPR domain with the intellectual disability associated mutation L254F
Descriptor: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
Authors:Gundogdu, M, van Aalten, D.M.F.
Deposit date:2017-10-10
Release date:2018-05-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The O-GlcNAc Transferase Intellectual Disability Mutation L254F Distorts the TPR Helix.
Cell Chem Biol, 25, 2018
3VTX
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BU of 3vtx by Molmil
Crystal structure of MamA protein
Descriptor: GLYCEROL, MamA
Authors:Zeytuni, N, Baran, D, Davidov, G, Zarivach, R.
Deposit date:2012-06-08
Release date:2012-10-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Inter-phylum structural conservation of the magnetosome-associated TPR-containing protein, MamA
J.Struct.Biol., 180, 2012
5JHE
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BU of 5jhe by Molmil
The Crystal Structure of the Saccharomyces cerevisiae Co-Chaperone Cpr7
Descriptor: Peptidyl-prolyl cis-trans isomerase CYP7
Authors:Yu, Q, Xu, L.
Deposit date:2016-04-20
Release date:2017-04-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of the Saccharomyces cerevisiae Co-Chaperone Cpr7
To Be Published
4GCN
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BU of 4gcn by Molmil
N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans
Descriptor: Protein STI-1, TRIETHYLENE GLYCOL
Authors:Osipiuk, J, Bigelow, L, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2012-07-30
Release date:2012-08-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans
To be Published
5OMP
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BU of 5omp by Molmil
Human FKBP5 protein
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP5, SULFATE ION
Authors:Kumar, R, Moche, M, Winblad, B, Pavlov, P.
Deposit date:2017-08-01
Release date:2017-11-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Combined x-ray crystallography and computational modeling approach to investigate the Hsp90 C-terminal peptide binding to FKBP51.
Sci Rep, 7, 2017
1ELR
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BU of 1elr by Molmil
Crystal structure of the TPR2A domain of HOP in complex with the HSP90 peptide MEEVD
Descriptor: HSP90-PEPTIDE MEEVD, NICKEL (II) ION, TPR2A-DOMAIN OF HOP
Authors:Scheufler, C, Brinker, A, Hartl, F.U, Moarefi, I.
Deposit date:2000-03-14
Release date:2000-04-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine.
Cell(Cambridge,Mass.), 101, 2000
3FP2
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BU of 3fp2 by Molmil
Crystal structure of Tom71 complexed with Hsp82 C-terminal fragment
Descriptor: ATP-dependent molecular chaperone HSP82, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Li, J, Qian, X, Hu, J, Sha, B.
Deposit date:2009-01-03
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
3FP3
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BU of 3fp3 by Molmil
Crystal structure of Tom71
Descriptor: CHLORIDE ION, SULFATE ION, TPR repeat-containing protein YHR117W
Authors:Li, J, Qian, X, Hu, J, Sha, B.
Deposit date:2009-01-03
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
5LYN
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BU of 5lyn by Molmil
Structure of the Tpr Domain of Sgt2 in complex with yeast Ssa1 peptide fragment
Descriptor: PRO-THR-VAL-GLU-GLU-VAL-ASP, Small glutamine-rich tetratricopeptide repeat-containing protein 2, ZINC ION
Authors:Krysztofinska, E.M, Evans, N.J, Thapaliya, A, Murray, J.W, Morgan, R.M.L, Martinez-Lumbreras, S, Isaacson, R.L.
Deposit date:2016-09-28
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp.
Front Mol Biosci, 4, 2017
3CVP
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BU of 3cvp by Molmil
Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to PTS1 peptide (10-SKL)
Descriptor: 10-SKL PTS1 peptide Ac-GTLSNRASKL, Peroxisome targeting signal 1 receptor PEX5
Authors:Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J.
Deposit date:2008-04-18
Release date:2008-06-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
J.Mol.Biol., 381, 2008
3CV0
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BU of 3cv0 by Molmil
Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to T. brucei Phosphoglucoisomerase (PGI) PTS1 peptide
Descriptor: 1,2-ETHANEDIOL, Peroxisome targeting signal 1 receptor PEX5, T. brucei PGI PTS1 peptide Ac-FNELSHL
Authors:Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J.
Deposit date:2008-04-17
Release date:2008-06-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
J.Mol.Biol., 381, 2008
3VTY
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BU of 3vty by Molmil
Crystal structure of MamA
Descriptor: CHLORIDE ION, MamA
Authors:Zeytuni, N, Baran, D, Davidov, G, Zarivach, R.
Deposit date:2012-06-08
Release date:2012-10-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inter-phylum structural conservation of the magnetosome-associated TPR-containing protein, MamA
J.Struct.Biol., 180, 2012
4JA7
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BU of 4ja7 by Molmil
Rat PP5 co-crystallized with P5SA-2
Descriptor: MAGNESIUM ION, Serine/threonine-protein phosphatase 5
Authors:Haslbeck, V, Helmuth, M, Alte, F, Popowicz, G, Schmidt, W, Weiwad, M, Fischer, G, Gemmecker, G, Sattler, M, Striggow, F, Groll, M, Richter, K.
Deposit date:2013-02-18
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism.
Biosci.Rep., 35, 2015
3ESK
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BU of 3esk by Molmil
Structure of HOP TPR2A domain in complex with the non-cognate Hsc70 peptide ligand
Descriptor: Heat shock cognate 71 kDa protein, NICKEL (II) ION, Stress-induced-phosphoprotein 1
Authors:Kajander, T, Regan, L.
Deposit date:2008-10-06
Release date:2009-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering.
J.Biol.Chem., 284, 2009
5JJT
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BU of 5jjt by Molmil
Crystal structure of a type 5 serine/threonine protein phosphatase from Arabidopsis thaliana
Descriptor: NICKEL (II) ION, Serine/threonine-protein phosphatase 5
Authors:Li, H.M, Pu, H.
Deposit date:2016-04-25
Release date:2017-04-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Crystal structure of a type 5 serine/threonine protein phosphatase from Arabidopsis thaliana
To Be Published
3FP4
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BU of 3fp4 by Molmil
Crystal structure of Tom71 complexed with Ssa1 C-terminal fragment
Descriptor: CHLORIDE ION, SODIUM ION, SULFATE ION, ...
Authors:Li, J, Qian, X, Hu, J, Sha, B.
Deposit date:2009-01-03
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
3LCA
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BU of 3lca by Molmil
Structure of Tom71 complexed with Hsp70 Ssa1 C terminal tail indicating conformational plasticity
Descriptor: GLYCEROL, Heat shock protein SSA1, Protein TOM71
Authors:Li, J.Z, Sha, B.D.
Deposit date:2010-01-10
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The structural plasticity of Tom71 for mitochondrial precursor translocations.
Acta Crystallogr.,Sect.F, 66, 2010
3FWV
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BU of 3fwv by Molmil
Crystal Structure of a Redesigned TPR Protein, T-MOD(VMY), in Complex with MEEVF Peptide
Descriptor: Heat shock protein HSP 90-beta, Hsc70/Hsp90-organizing protein, NICKEL (II) ION
Authors:Jackrel, M.E, Valverde, R, Regan, L.
Deposit date:2009-01-19
Release date:2009-04-21
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Redesign of a protein-peptide interaction: characterization and applications
Protein Sci., 18, 2009
7DHG
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BU of 7dhg by Molmil
Crystal structure of SARS-CoV-2 Orf9b complex with human TOM70
Descriptor: Mitochondrial import receptor subunit TOM70, ORF9b protein
Authors:Gao, X, Zhu, K, Qin, B, Olieric, V, Wang, M, Cui, S.
Deposit date:2020-11-14
Release date:2021-05-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions.
Nat Commun, 12, 2021
5OJ8
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BU of 5oj8 by Molmil
Crystal structure of the KLC1-TPR domain ([A1-B5] fragment)
Descriptor: Kinesin light chain 1, PHOSPHATE ION
Authors:Nguyen, T.Q, Chenon, M, Vilela, F, Velours, C, Fernandez-Varela, P, Llinas, P, Menetrey, J.
Deposit date:2017-07-20
Release date:2017-10-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.247 Å)
Cite:Structural plasticity of the N-terminal capping helix of the TPR domain of kinesin light chain.
PLoS ONE, 12, 2017
6FV0
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BU of 6fv0 by Molmil
Crystal structure of the TPR domain of KLC1 in complex with the C-terminal peptide of torsinA
Descriptor: DI(HYDROXYETHYL)ETHER, Kinesin light chain 1,Torsin-1A, nanobody
Authors:Pernigo, S, Dodding, M.P, Steiner, R.A.
Deposit date:2018-02-28
Release date:2018-03-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors.
Elife, 7, 2018

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