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4JA7

Rat PP5 co-crystallized with P5SA-2

Summary for 4JA7
Entry DOI10.2210/pdb4ja7/pdb
Related1WAO 4JA9
DescriptorSerine/threonine-protein phosphatase 5, MAGNESIUM ION (3 entities in total)
Functional Keywordspp5, activation, tau-dephosphorylation, neurodegenerative disease, ser/thr-protein phosphatase domain, tetratricopeptide repeat domain, hsp90, hydrolase
Biological sourceRattus norvegicus (brown rat,rat,rats)
Cellular locationNucleus : P53042
Total number of polymer chains1
Total formula weight55847.85
Authors
Haslbeck, V.,Helmuth, M.,Alte, F.,Popowicz, G.,Schmidt, W.,Weiwad, M.,Fischer, G.,Gemmecker, G.,Sattler, M.,Striggow, F.,Groll, M.,Richter, K. (deposition date: 2013-02-18, release date: 2014-02-19, Last modification date: 2023-09-20)
Primary citationHaslbeck, V.,Drazic, A.,Eckl, J.M.,Alte, F.,Helmuth, M.,Popowicz, G.,Schmidt, W.,Braun, F.,Weiwad, M.,Fischer, G.,Gemmecker, G.,Sattler, M.,Striggow, F.,Groll, M.,Richter, K.
Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism.
Biosci.Rep., 35:-, 2015
Cited by
PubMed: 26182372
DOI: 10.1042/BSR20150042
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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