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1BNC	THREE-DIMENSIONAL STRUCTURE OF THE BIOTIN CARBOXYLASE SUBUNIT OF ACETYL-COA CARBOXYLASE Descriptor: BIOTIN CARBOXYLASE, PHOSPHATE ION Authors: Waldrop, G, Rayment, I, Holden, H.M. Deposit date: 1994-07-06 Release date: 1995-08-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Three-dimensional structure of the biotin carboxylase subunit of acetyl-CoA carboxylase. Biochemistry, 33, 1994
1DV1	STRUCTURE OF BIOTIN CARBOXYLASE (APO) Descriptor: BIOTIN CARBOXYLASE, PHOSPHATE ION Authors: Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L. Deposit date: 2000-01-19 Release date: 2000-06-09 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Movement of the biotin carboxylase B-domain as a result of ATP binding. J.Biol.Chem., 275, 2000
1DV2	The structure of biotin carboxylase, mutant E288K, complexed with ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, BIOTIN CARBOXYLASE Authors: Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L. Deposit date: 2000-01-19 Release date: 2000-06-09 Last modified: 2022-12-21 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Movement of the biotin carboxylase B-domain as a result of ATP binding. J.Biol.Chem., 275, 2000
1ULZ	Crystal structure of the biotin carboxylase subunit of pyruvate carboxylase Descriptor: pyruvate carboxylase n-terminal domain Authors: Kondo, S, Nakajima, Y, Sugio, S, Yong-Biao, J, Sueda, S, Kondo, H. Deposit date: 2003-09-18 Release date: 2004-03-09 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of the biotin carboxylase subunit of pyruvate carboxylase from Aquifex aeolicus at 2.2 A resolution. Acta Crystallogr.,Sect.D, 60, 2004
1W93	Crystal Structure of Biotin Carboxylase Domain of Acetyl-Coenzyme A Carboxylase from Saccharomyces cerevisiae Descriptor: ACETYL-COENZYME A CARBOXYLASE Authors: Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L. Deposit date: 2004-10-05 Release date: 2005-01-04 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product Mol.Cell, 16, 2004
1W96	Crystal Structure of Biotin Carboxylase Domain of Acetyl-coenzyme A Carboxylase from Saccharomyces cerevisiae in Complex with Soraphen A Descriptor: ACETYL-COENZYME A CARBOXYLASE, SORAPHEN A Authors: Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L. Deposit date: 2004-10-06 Release date: 2005-01-04 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product Mol.Cell, 16, 2004
2GPW	Crystal Structure of the Biotin Carboxylase Subunit, F363A Mutant, of Acetyl-CoA Carboxylase from Escherichia coli. Descriptor: Biotin carboxylase Authors: Shen, Y, Chou, C.Y, Chang, G.G, Tong, L. Deposit date: 2006-04-18 Release date: 2006-07-04 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Is dimerization required for the catalytic activity of bacterial biotin carboxylase? Mol.Cell, 22, 2006
2GPS	Crystal Structure of the Biotin Carboxylase Subunit, E23R mutant, of Acetyl-CoA Carboxylase from Escherichia coli. Descriptor: Biotin carboxylase Authors: Shen, Y, Chou, C.Y, Chang, G.G, Tong, L. Deposit date: 2006-04-18 Release date: 2006-07-04 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Is dimerization required for the catalytic activity of bacterial biotin carboxylase? Mol.Cell, 22, 2006
2HJW	Crystal Structure of the BC domain of ACC2 Descriptor: Acetyl-CoA carboxylase 2 Authors: Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S. Deposit date: 2006-07-02 Release date: 2007-07-03 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2. Proteins, 70, 2008
2DZD	Crystal structure of the biotin carboxylase domain of pyruvate carboxylase Descriptor: pyruvate carboxylase Authors: Kondo, S, Nakajima, Y, Sugio, S, Sueda, S, Islam, M.N, Kondo, H. Deposit date: 2006-09-27 Release date: 2007-09-25 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure of the biotin carboxylase domain of pyruvate carboxylase from Bacillus thermodenitrificans ACTA CRYSTALLOGR.,SECT.D, 63, 2007
2QF7	Crystal structure of a complete multifunctional pyruvate carboxylase from Rhizobium etli Descriptor: CHLORIDE ION, COENZYME A, FORMIC ACID, ... Authors: St Maurice, M, Surinya, K.H, Rayment, I. Deposit date: 2007-06-27 Release date: 2007-09-04 Last modified: 2012-02-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme Science, 317, 2007
3BG5	Crystal Structure of Staphylococcus Aureus Pyruvate Carboxylase Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Xiang, S, Tong, L. Deposit date: 2007-11-26 Release date: 2008-02-26 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. Nat.Struct.Mol.Biol., 15, 2008
2VPQ	Crystal structure of biotin carboxylase from S. aureus complexed with AMPPNP Descriptor: ACETYL-COA CARBOXYLASE, CHLORIDE ION, MAGNESIUM ION, ... Authors: Mochalkin, I. Deposit date: 2008-03-03 Release date: 2008-09-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2VQD	Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa complexed with AMPCP Descriptor: BIOTIN CARBOXYLASE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... Authors: Mochalkin, I. Deposit date: 2008-03-13 Release date: 2008-09-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2C00	Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa in apo form Descriptor: BIOTIN CARBOXYLASE, SULFATE ION Authors: Mochalkin, I. Deposit date: 2008-03-21 Release date: 2008-09-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2J9G	Crystal structure of Biotin carboxylase from E. coli in complex with AMPPNP and ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, BIOTIN CARBOXYLASE, MAGNESIUM ION, ... Authors: Mochalkin, I. Deposit date: 2008-03-21 Release date: 2008-09-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2VR1	Crystal structure of Biotin carboxylase from E. coli in complex with ATP analog, ADPCF2P. Descriptor: BIOTIN CARBOXYLASE, CHLORIDE ION, PHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER Authors: Mochalkin, I, Waldrop, G.L. Deposit date: 2008-03-24 Release date: 2008-09-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2V5A	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 3 Descriptor: 7-(2,5-dihydropyrrol-1-yl)-6-phenyl-pyrido[6,5-d]pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-10-02 Release date: 2009-01-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.31 Å) Cite: A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2V59	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 2 Descriptor: 6-(2,6-DIMETHOXYPHENYL)PYRIDO[2,3-D]PYRIMIDINE-2,7-DIAMINE, BIOTIN CARBOXYLASE Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-10-02 Release date: 2009-01-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2V58	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 1 Descriptor: 6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-10-02 Release date: 2009-01-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2W6M	Crystal structure of Biotin carboxylase from E. coli in complex with amino-oxazole fragment series Descriptor: (2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6P	Crystal structure of Biotin carboxylase from E. coli in complex with 5-Methyl-6-phenyl-quinazoline-2,4-diamine Descriptor: 5-methyl-6-phenylquinazoline-2,4-diamine, ACETYL-COA CARBOXYLASE Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6N	Crystal structure of Biotin carboxylase from E. coli in complex with amino-oxazole fragment series Descriptor: 2-AMINO-N,N-BIS(PHENYLMETHYL)-1,3-OXAZOLE-5-CARBOXAMIDE, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6O	Crystal structure of Biotin carboxylase from E. coli in complex with 4-Amino-7,7-dimethyl-7,8-dihydro-quinazolinone fragment Descriptor: 4-amino-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6Q	Crystal structure of Biotin carboxylase from E. coli in complex with the triazine-2,4-diamine fragment Descriptor: 6-(2-phenoxyethoxy)-1,3,5-triazine-2,4-diamine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009

 

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