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1W4R
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1w4r
STRUCTURE OF A TYPE II THYMIDINE KINASE WITH BOUND DTTP
Descriptor:THYMIDINE KINASE (E.C.2.7.1.21)
Authors:Birringer, M.S., Claus, M.T., Folkers, G., Kloer, D.P., Schulz, G.E., Scapozza, L.
Deposit date:2004-07-27
Release date:2005-02-01
Modification date:2013-03-06
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure of a Type II Thymidine Kinase with Bound Dttp
FEBS Lett., 579, 2005
1XBT
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1xbt
CRYSTAL STRUCTURE OF HUMAN THYMIDINE KINASE 1
Descriptor:Thymidine kinase, cytosolic(E.C.2.7.1.21)
Authors:Welin, M., Kosinska, U., Mikkelsen, N.E., Carnrot, C., Zhu, C., Wang, L., Eriksson, S., Munch-Petersen, B., Eklund, H.
Deposit date:2004-08-31
Release date:2004-12-14
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of thymidine kinase 1 of human and mycoplasmic origin
Proc.Natl.Acad.Sci.Usa, 101, 2004
1XX6
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1xx6
X-RAY STRUCTURE OF CLOSTRIDIUM ACETOBUTYLICUM THYMIDINE KINASE WITH ADP. NORTHEAST STRUCTURAL GENOMICS TARGET CAR26.
Descriptor:Thymidine kinase
Authors:Kuzin, A.P., Abashidze, M., Forouhar, F., Vorobiev, S.M., Acton, T.B., Ma, L.-C., Xiao, R., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2004-11-04
Release date:2004-12-21
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of Clostridium acetobutylicum thymidine kinase with ADP. Northeast Structural Genomics Target CAR26.
To be Published
2B8T
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2b8t
CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM U.UREALYTICUM IN COMPLEX WITH THYMIDINE
Descriptor:Thymidine kinase (E.C.2.7.1.21)
Authors:Kosinska, U., Carnrot, C., Eriksson, S., Wang, L., Eklund, H.
Deposit date:2005-10-10
Release date:2005-12-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the substrate complex of thymidine kinase from Ureaplasma urealyticum and investigations of possible drug targets for the enzyme
FEBS Lett., 272, 2005
2J87
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2j87
STRUCTURE OF VACCINIA VIRUS THYMIDINE KINASE IN COMPLEX WITH DTTP: INSIGHTS FOR DRUG DESIGN
Descriptor:THYMIDINE KINASE (E.C.2.7.1.21)
Authors:El Omari, K., Solaroli, N., Karlsson, A., Balzarini, J., Stammers, D.K.
Deposit date:2006-10-23
Release date:2006-11-13
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of Vaccinia Virus Thymidine Kinase in Complex with Dttp: Insights for Drug Design.
Bmc Struct.Biol., 6, 2006
2J9R
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2j9r
THYMIDINE KINASE FROM B. ANTHRACIS IN COMPLEX WITH DT.
Descriptor:THYMIDINE KINASE (E.C.2.7.1.21)
Authors:Kosinska, U., Carnrot, C., Sandrini, M.P.B., Clausen, A.R., Wang, L., Piskur, J., Eriksson, S., Eklund, H.
Deposit date:2006-11-15
Release date:2007-01-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding
FEBS J., 274, 2007
2JA1
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2ja1
THYMIDINE KINASE FROM B. CEREUS WITH TTP BOUND AS PHOSPHATE DONOR.
Descriptor:THYMIDINE KINASE (E.C.2.7.1.21)
Authors:Kosinska, U., Carnrot, C., Sandrini, M.P.B., Clausen, A.R., Wang, L., Piskur, J., Eriksson, S., Eklund, H.
Deposit date:2006-11-17
Release date:2007-01-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding
FEBS J., 274, 2007
2ORV
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2orv
HUMAN THYMIDINE KINASE 1 IN COMPLEX WITH TP4A
Descriptor:Thymidine kinase (E.C.2.7.1.21)
Authors:Segura-Pena, D., Lutz, S., Monnerjahn, C., Konrad, M., Lavie, A.
Deposit date:2007-02-04
Release date:2007-03-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding of ATP to TK1-like Enzymes Is Associated with a Conformational Change in the Quaternary Structure.
J.Mol.Biol., 369, 2007
2ORW
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2orw
THERMOTOGA MARITIMA THYMIDINE KINASE 1 LIKE ENZYME IN COMPLEX WITH TP4A
Descriptor:Thymidine kinase (E.C.2.7.1.21)
Authors:Segura-Pena, D., Lutz, S., Monnerjahn, C., Konrad, M., Lavie, A.
Deposit date:2007-02-04
Release date:2007-03-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Binding of ATP to TK1-like Enzymes Is Associated with a Conformational Change in the Quaternary Structure.
J.Mol.Biol., 369, 2007
2QPO
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2qpo
THERMOTOGA MARITIMA THYMIDINE KINASE IN THE APO FORM
Descriptor:Thymidine kinase (E.C.2.7.1.21)
Authors:Segura-Pena, D., Lichter, J., Trani, M., Konrad, M., Lavie, A., Lutz, S.
Deposit date:2007-07-24
Release date:2007-10-16
Modification date:2008-12-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes.
Structure, 15, 2007
2QQ0
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2qq0
THYMIDINE KINASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH THYMIDINE + APPNHP
Descriptor:Thymidine kinase (E.C.2.7.1.21)
Authors:Segura-Pena, D., Lichter, J., Trani, M., Konrad, M., Lavie, A., Lutz, S.
Deposit date:2007-07-25
Release date:2007-10-16
Modification date:2008-12-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes.
Structure, 15, 2007
2QQE
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2qqe
THYMIDINE KINASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH THYMIDINE
Descriptor:Thymidine kinase (E.C.2.7.1.21)
Authors:Segura-Pena, D., Lichter, J., Trani, M., Konrad, M., Lavie, A., Lutz, S.
Deposit date:2007-07-26
Release date:2007-10-16
Modification date:2008-12-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes.
Structure, 15, 2007
2UZ3
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2uz3
CRYSTAL STRUCTURE OF THYMIDINE KINASE WITH DTTP FROM U. UREALYTICUM
Descriptor:THYMIDINE KINASE (E.C.2.7.1.21)
Authors:Welin, M., Kosinska, U., Mikkelsen, N.E., Carnrot, C., Zhu, C., Wang, L., Eriksson, S., Munch-Petersen, B., Eklund, H.
Deposit date:2007-04-24
Release date:2007-05-29
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of Thymidine Kinase 1 of Human and Mycoplasmic Origin
Proc.Natl.Acad.Sci.USA, 101, 2004
2WVJ
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2wvj
MUTATION OF THR163 TO SER IN HUMAN THYMIDINE KINASE SHIFTS THE SPECIFICITY FROM THYMIDINE TOWARDS THE NUCLEOSIDE ANALOGUE AZIDOTHYMIDINE
Descriptor:THYMIDINE KINASE, CYTOSOLIC (E.C.2.7.1.21)
Authors:Skovgaard, T., Uhlin, U., Munch-Petersen, B.
Deposit date:2009-10-17
Release date:2009-10-27
Modification date:2012-05-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Comparative Active-Site Mutation Study of Human and Caenorhabditis Elegans Thymidine Kinase 1.
FEBS J., 279, 2012
3E2I
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3e2i
CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM S. AUREUS
Descriptor:Thymidine kinase (E.C.2.7.1.21)
Authors:Lam, R., Johns, K., Battaile, K.P., Romanov, V., Lam, K., Pai, E.F., Chirgadze, N.Y.
Deposit date:2008-08-05
Release date:2009-08-11
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structure of Thymidine Kinase from S. aureus
To be Published
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entries available on 2014-10-29
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