1XBT

Crystal Structure of Human Thymidine Kinase 1

Summary for 1XBT

Entry DOI	10.2210/pdb1xbt/pdb
Descriptor	Thymidine kinase, cytosolic, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	deoxyribonucleoside kinase, zinc-binding domain, feedback inhibitor, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P04183
Total number of polymer chains	8
Total formula weight	175191.06
Authors	Welin, M.,Kosinska, U.,Mikkelsen, N.E.,Carnrot, C.,Zhu, C.,Wang, L.,Eriksson, S.,Munch-Petersen, B.,Eklund, H. (deposition date: 2004-08-31, release date: 2004-12-14, Last modification date: 2024-03-13)
Primary citation	Welin, M.,Kosinska, U.,Mikkelsen, N.E.,Carnrot, C.,Zhu, C.,Wang, L.,Eriksson, S.,Munch-Petersen, B.,Eklund, H. Structures of thymidine kinase 1 of human and mycoplasmic origin Proc.Natl.Acad.Sci.Usa, 101:17970-17975, 2004 Cited by PubMed: 15611477 DOI: 10.1073/pnas.0406332102 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation