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1AU1
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1au1
HUMAN INTERFERON-BETA CRYSTAL STRUCTURE
Descriptor:INTERFERON-BETA
Authors:Karpusas, M., Nolte, M., Lipscomb, W.
Deposit date:1997-09-09
Release date:1998-06-17
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of human interferon beta at 2.2-A resolution.
Proc.Natl.Acad.Sci.USA, 94, 1997
1B5L
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1b5l
OVINE INTERFERON TAU
Descriptor:INTERFERON TAU
Authors:Radhakrishnan, R., Walter, L.J., Subramaniam, P.S., Johnson, H.J., Walter, M.R.
Deposit date:1999-01-07
Release date:1999-05-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of ovine interferon-tau at 2.1 A resolution.
J.Mol.Biol., 286, 1999
1IFA
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1ifa
THREE-DIMENSIONAL CRYSTAL STRUCTURE OF RECOMBINANT MURINE INTERFERON-BETA
Descriptor:INTERFERON BETA (MURINE)
Authors:Mitsui, Y., Senda, T., Matsuda, S., Kawano, G., Nakamura, K.T., Shimizu, H.
Deposit date:1991-10-29
Release date:1994-01-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Three-dimensional crystal structure of recombinant murine interferon-beta.
EMBO J., 11, 1992
1ITF
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1itf
INTERFERON ALPHA-2A, NMR, 24 STRUCTURES
Descriptor:INTERFERON ALPHA-2A
Authors:Klaus, W., Gsell, B., Labhardt, A.M., Wipf, B., Senn, H.
Deposit date:1997-08-22
Release date:1997-12-03
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The three-dimensional high resolution structure of human interferon alpha-2a determined by heteronuclear NMR spectroscopy in solution.
J.Mol.Biol., 274, 1997
1RH2
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1rh2
RECOMBINANT HUMAN INTERFERON-ALPHA 2B
Descriptor:INTERFERON-ALPHA 2B
Authors:Walter, M.R.
Deposit date:1996-11-07
Release date:1997-11-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography.
Structure, 4, 1996
1WU3
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1wu3
CRYSTAL STRUCTURE OF RECOMBINANT MURINE INTERFERON BETA
Descriptor:Interferon beta
Authors:Senda, T., Saitoh, S., Mitsui, Y.
Deposit date:2004-12-01
Release date:2004-12-14
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Refined crystal structure of recombinant murine interferon-beta at 2.15 A resolution
J.Mol.Biol., 253, 1995
2LMS
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2lms
A SINGLE GALNAC RESIDUE ON THREONINE-106 MODIFIES THE DYNAMICS AND THE STRUCTURE OF INTERFERON ALPHA-2A AROUND THE GLYCOSYLATION SITE
Descriptor:Interferon alpha-2
Authors:Ghasriani, H., Belcourt, P.J.F., Sauve, S., Hodgson, D.J., Gingras, G., Brochu, D., Gilbert, M., Aubin, Y.
Deposit date:2011-12-12
Release date:2012-12-05
Modification date:2013-05-01
Method:SOLUTION NMR
Cite:A single N-acetylgalactosamine residue at threonine 106 modifies the dynamics and structure of interferon alpha2a around the glycosylation site.
J.Biol.Chem., 288, 2013
3PIV
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3piv
ZEBRAFISH INTERFERON 1
Descriptor:Interferon
Authors:Hamming, O.J., Hartmann, R., Lutfalla, G., Levraud, J.-P.
Deposit date:2010-11-08
Release date:2011-07-20
Modification date:2011-08-03
Method:X-RAY DIFFRACTION (2.086 Å)
Cite:Crystal Structure of Zebrafish Interferons I and II Reveals Conservation of Type I Interferon Structure in Vertebrates.
J.Virol., 85, 2011
3PIW
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3piw
ZEBRAFISH INTERFERON 2
Descriptor:Type I interferon 2
Authors:Hamming, O.J., Hartmann, R., Lutfalla, G., Levraud, J.-P.
Deposit date:2010-11-08
Release date:2011-07-20
Modification date:2011-08-03
Method:X-RAY DIFFRACTION (1.492 Å)
Cite:Crystal Structure of Zebrafish Interferons I and II Reveals Conservation of Type I Interferon Structure in Vertebrates.
J.Virol., 85, 2011
2KZ1
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2kz1
INTER-MOLECULAR INTERACTIONS IN A 44 KDA INTERFERON-RECEPTOR COMPLEX DETECTED BY ASYMMETRIC BACK-PROTONATION AND 2D NOESY
Descriptor:Interferon alpha-2, Soluble IFN alpha/beta receptor
Authors:Nudelman, I., Akabayov, S.R., Schnur, E., Biron, Z., Levy, R., Xu, Y., Yang, D., Anglister, J.
Deposit date:2010-06-10
Release date:2010-06-23
Modification date:2010-07-07
Method:SOLUTION NMR
Cite:Intermolecular interactions in a 44 kDa interferon-receptor complex detected by asymmetric reverse-protonation and two-dimensional NOESY
Biochemistry, 49, 2010
3OQ3
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3oq3
STRUCTURAL BASIS OF TYPE-I INTERFERON SEQUESTRATION BY A POXVIRUS DECOY RECEPTOR
Descriptor:Interferon alpha-5, IFN-alpha/beta binding protein C12R
Authors:Fremont, D.H., Lee, C.A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-09-02
Release date:2011-05-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis of Type-I Interferon Sequestration by a Poxvirus Decoy Receptor
To be Published
3S9D
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3s9d
BINARY COMPLEX BETWEEN IFNA2 AND IFNAR2
Descriptor:Interferon alpha-2, Interferon alpha/beta receptor 2
Authors:Thomas, C., Garcia, K.C.
Deposit date:2011-06-01
Release date:2011-08-31
Modification date:2012-03-21
Method:X-RAY DIFFRACTION (1.9999 Å)
Cite:Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell(Cambridge,Mass.), 146, 2011
3UX9
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3ux9
STRUCTURAL INSIGHTS INTO A HUMAN ANTI-IFN ANTIBODY EXERTING THERAPEUTIC POTENTIAL FOR SYSTEMIC LUPUS ERYTHEMATOSUS
Descriptor:Interferon alpha-1/13, ScFv antibody
Authors:Ouyang, S., Zhao, L.X., Liang, W., Shaw, N., Liu, Z.-J., Liang, M.-F.
Deposit date:2011-12-04
Release date:2012-02-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus
J.Mol.Med., 2012
2HYM
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2hym
NMR BASED DOCKING MODEL OF THE COMPLEX BETWEEN THE HUMAN TYPE I INTERFERON RECEPTOR AND HUMAN INTERFERON ALPHA-2
Descriptor:Soluble IFN alpha/beta receptor, Interferon alpha-2
Authors:Quadt-Akabayov, S.R., Chill, J.H., Levy, R., Kessler, N., Anglister, J.
Deposit date:2006-08-07
Release date:2006-10-10
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Determination of the human type I interferon receptor binding site on human interferon-alpha2 by cross saturation and an NMR-based model of the complex
Protein Sci., 15, 2006
2LAG
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2lag
STRUCTURE OF THE 44 KDA COMPLEX OF INTERFERON-ALPHA2 WITH THE EXTRACELLULAR PART OF IFNAR2 OBTAINED BY 2D-DOUBLE DIFFERENCE NOESY
Descriptor:Interferon alpha/beta receptor 2, Interferon alpha-2
Authors:Nudelman, I., Akabayov, S.R., Scherf, T., Anglister, J.
Deposit date:2011-03-13
Release date:2011-08-17
Modification date:2011-09-28
Method:SOLUTION NMR
Cite:Observation of Intermolecular Interactions in Large Protein Complexes by 2D-Double Difference Nuclear Overhauser Enhancement Spectroscopy: Application to the 44 kDa Interferon-Receptor Complex.
J.Am.Chem.Soc., 133, 2011
3SE3
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3se3
HUMAN IFNA2-IFNAR TERNARY COMPLEX
Descriptor:Interferon alpha/beta receptor 1, Interferon alpha 2b, Interferon alpha/beta receptor 2
Authors:Thomas, C., Garcia, K.C.
Deposit date:2011-06-10
Release date:2011-08-31
Modification date:2013-08-21
Method:X-RAY DIFFRACTION (4.0001 Å)
Cite:Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell(Cambridge,Mass.), 146, 2011
3SE4
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3se4
HUMAN IFNW-IFNAR TERNARY COMPLEX
Descriptor:Interferon alpha/beta receptor 1, Interferon omega-1, Interferon alpha/beta receptor 2
Authors:Thomas, C., Garcia, K.C.
Deposit date:2011-06-10
Release date:2011-08-31
Modification date:2012-03-21
Method:X-RAY DIFFRACTION (3.5001 Å)
Cite:Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell(Cambridge,Mass.), 146, 2011
3WCY
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3wcy
MURINE IFNAR1 IN COMPLEX WITH INTERFERON-BETA
Descriptor:Interferon alpha/beta receptor 1, Interferon beta
Authors:Vivian, J.P., de Weerd, N.A., Hertzog, P.J., Rossjohn, J.
Deposit date:2013-06-04
Release date:2013-07-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of a unique interferon beta signaling axis mediated via the IFNAR1 receptor
To be Published
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entries available on 2014-10-01
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