2LAG
Structure of the 44 kDa complex of interferon-alpha2 with the extracellular part of IFNAR2 obtained by 2D-double difference NOESY
Summary for 2LAG
Entry DOI | 10.2210/pdb2lag/pdb |
Related | 1kz1 |
NMR Information | BMRB: 16677 |
Descriptor | Interferon alpha/beta receptor 2, Interferon alpha-2 (2 entities in total) |
Functional Keywords | interferon, receptor, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P48551 Isoform 1: Membrane; Single-pass type I membrane protein. Isoform 2: Membrane; Single-pass type I membrane protein. Isoform 3: Secreted: P01563 |
Total number of polymer chains | 2 |
Total formula weight | 43587.53 |
Authors | Nudelman, I.,Akabayov, S.R.,Scherf, T.,Anglister, J. (deposition date: 2011-03-13, release date: 2011-08-17, Last modification date: 2011-09-28) |
Primary citation | Nudelman, I.,Akabayov, S.R.,Scherf, T.,Anglister, J. Observation of Intermolecular Interactions in Large Protein Complexes by 2D-Double Difference Nuclear Overhauser Enhancement Spectroscopy: Application to the 44 kDa Interferon-Receptor Complex. J.Am.Chem.Soc., 133:14755-14764, 2011 Cited by PubMed: 21819146DOI: 10.1021/ja205480v PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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