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1A27
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1a27
HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 C-TERMINAL DELETION MUTANT COMPLEXED WITH ESTRADIOL AND NADP+
Descriptor:17-BETA-HYDROXYSTEROID-DEHYDROGENASE, ESTRADIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Mazza, C., Breton, R., Housset, D., Fontecilla-Camps, J.-C.
Deposit date:1998-01-16
Release date:1998-05-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Human Type I 17Beta-Hydroxysteroid Dehydrogenase: Site Directed Mutagenesis and X-Ray Crystallography Structure-Function Analysis
Thesis, Universite Joseph Fourier, 1997
1A4U
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1a4u
ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS
Descriptor:ALCOHOL DEHYDROGENASE
Authors:Benach, J., Atrian, S., Gonzalez-Duarte, R., Ladenstein, R.
Deposit date:1998-02-05
Release date:1999-02-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:The refined crystal structure of Drosophila lebanonensis alcohol dehydrogenase at 1.9 A resolution.
J.Mol.Biol., 282, 1998
1AE1
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1ae1
TROPINONE REDUCTASE-I COMPLEX WITH NADP
Descriptor:TROPINONE REDUCTASE-I, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Nakajima, K., Yamashita, A., Akama, H., Nakatsu, T., Kato, H., Hashimoto, T., Oda, J., Yamada, Y.
Deposit date:1997-10-23
Release date:1998-11-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of two tropinone reductases: different reaction stereospecificities in the same protein fold.
Proc.Natl.Acad.Sci.USA, 95, 1998
1AHH
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1ahh
7 ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEXED WITH NAD+
Descriptor:7 ALPHA-HYDROXYSTEROID DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Tanaka, N., Nonaka, T., Mitsui, Y.
Deposit date:1995-08-25
Release date:1996-10-14
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of the binary and ternary complexes of 7 alpha-hydroxysteroid dehydrogenase from Escherichia coli.
Biochemistry, 35, 1996
1AHI
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1ahi
7 ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEXED WITH NADH AND 7-OXO GLYCOCHENODEOXYCHOLIC ACID
Descriptor:7 ALPHA-HYDROXYSTEROID DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Tanaka, N., Nonaka, T., Mitsui, Y.
Deposit date:1995-08-25
Release date:1996-10-14
Modification date:2013-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of the binary and ternary complexes of 7 alpha-hydroxysteroid dehydrogenase from Escherichia coli.
Biochemistry, 35, 1996
1B14
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1b14
ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS BINARY COMPLEX WITH NAD+
Descriptor:ALCOHOL DEHYDROGENASE (E.C.1.1.1.1)
Authors:Benach, J., Atrian, S., Gonzalez-Duarte, R., Ladenstein, R.
Deposit date:1998-11-25
Release date:1999-11-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography.
J.Mol.Biol., 289, 1999
1B15
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1b15
ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS TERNARY COMPLEX WITH NAD-ACETONE
Descriptor:ALCOHOL DEHYDROGENASE (E.C.1.1.1.1)
Authors:Benach, J., Atrian, S., Gonzalez-Duarte, R., Ladenstein, R.
Deposit date:1998-11-25
Release date:1999-11-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography.
J.Mol.Biol., 289, 1999
1B16
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1b16
ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS TERNARY COMPLEX WITH NAD-3-PENTANONE
Descriptor:PROTEIN (ALCOHOL DEHYDROGENASE) (1.1.1.1)
Authors:Benach, J., Atrian, S., Gonzalez-Duarte, R., Ladenstein, R.
Deposit date:1998-11-25
Release date:1999-11-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography.
J.Mol.Biol., 289, 1999
1B2L
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1b2l
ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS: TERNARY COMPLEX WITH NAD-CYCLOHEXANONE
Descriptor:ALCOHOL DEHYDROGENASE (E.C.1.1.1.1)
Authors:Benach, J., Atrian, S., Gonzalez-Duarte, R., Ladenstein, R.
Deposit date:1998-11-26
Release date:1999-11-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography.
J.Mol.Biol., 289, 1999
1BDB
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1bdb
CIS-BIPHENYL-2,3-DIHYDRODIOL-2,3-DEHYDROGENASE FROM PSEUDOMONAS SP. LB400
Descriptor:CIS-BIPHENYL-2,3-DIHYDRODIOL-2,3-DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Huelsmeyer, M., Hecht, H.-J., Niefind, K., Hofer, B., Timmis, K.N., Schomburg, D.
Deposit date:1997-05-10
Release date:1997-11-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase from a PCB degrader at 2.0 A resolution.
Protein Sci., 7, 1998
1BHS
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1bhs
HUMAN ESTROGENIC 17BETA-HYDROXYSTEROID DEHYDROGENASE
Descriptor:17BETA-HYDROXYSTEROID DEHYDROGENASE
Authors:Ghosh, D.
Deposit date:1995-04-19
Release date:1996-12-07
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase at 2.20 A resolution.
Structure, 3, 1995
1CYD
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1cyd
CARBONYL REDUCTASE COMPLEXED WITH NADPH AND 2-PROPANOL
Descriptor:CARBONYL REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Tanaka, N., Nonaka, T., Mitsui, Y.
Deposit date:1995-09-01
Release date:1996-10-14
Modification date:2013-12-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the ternary complex of mouse lung carbonyl reductase at 1.8 A resolution: the structural origin of coenzyme specificity in the short-chain dehydrogenase/reductase family.
Structure, 4, 1996
1DHR
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1dhr
CRYSTAL STRUCTURE OF RAT LIVER DIHYDROPTERIDINE REDUCTASE
Descriptor:DIHYDROPTERIDINE REDUCTASE (DHPR) (E.C.1.6.99.10) COMPLEX WITH NADH
Authors:Varughese, K.I., Skinner, M.M., Whiteley, J.M., Matthews, D.A., Xuong, N.H.
Deposit date:1992-03-30
Release date:1993-07-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of rat liver dihydropteridine reductase.
Proc.Natl.Acad.Sci.USA, 89, 1992
1DHT
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1dht
ESTROGENIC 17-BETA HYDROXYSTEROID DEHYDROGENASE COMPLEXED DIHYDROTESTOSTERONE
Descriptor:ESTROGENIC 17-BETA HYDROXYSTEROID DEHYDROGENASE, DIHYDROTESTOSTERONE
Authors:Han, Q., Campbell, R.L., Gangloff, A., Lin, S.X.
Deposit date:1998-03-25
Release date:1999-09-25
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Dehydroepiandrosterone and dihydrotestosterone recognition by human estrogenic 17beta-hydroxysteroid dehydrogenase. C-18/c-19 steroid discrimination and enzyme-induced strain.
J.Biol.Chem., 275, 2000
1DIR
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1dir
CRYSTAL STRUCTURE OF A MONOCLINIC FORM OF DIHYDROPTERIDINE REDUCTASE FROM RAT LIVER
Descriptor:DIHYDROPTERIDINE REDUCTASE (DHPR) (E.C.1.6.99.7)
Authors:Varughese, K.I., Su, Y., Skinner, M.M., Matthews, D.A., Whitely, J.M., Xuong, N.H.
Deposit date:1994-04-18
Release date:1994-07-31
Modification date:2014-02-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a monoclinic form of dihydropteridine reductase from rat liver.
Acta Crystallogr.,Sect.D, 50, 1994
1DOH
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1doh
STRUCTURE OF TRIHYDROXYNAPHTHALENE REDUCTASE IN COMPLEX WITH NADPH AND 4-NITRO-INDEN-1-ONE
Descriptor:TRIHYDROXYNAPHTHALENE REDUCTASE (E.C.1.1.1.252)
Authors:Liao, D.I., Basarab, G.S., Gatenby, A.A., Jordan, D.B.
Deposit date:1999-12-20
Release date:2001-06-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of trihydroxynaphthalene reductase-fungicide complexes: implications for structure-based design and catalysis.
Structure, 9, 2001
1E3S
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1e3s
RAT BRAIN 3-HYDROXYACYL-COA DEHYDROGENASE BINARY COMPLEX WITH NADH
Descriptor:SHORT CHAIN 3-HYDROXYACYL-COA DEHYDROGENASE (E.C.1.1.1.35)
Authors:Powell, A.J., Read, J.A., Banfield, M.J., Brady, R.L.
Deposit date:2000-06-22
Release date:2001-05-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition of Structurally Diverse Substrates by Type II 3-Hydroxyacyl-Coa Dehydrogenase (Hadh II) Amyloid-Beta Binding Alcohol Dehydrogenase (Abad)
J.Mol.Biol., 303, 2000
1E6W
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1e6w
RAT BRAIN 3-HYDROXYACYL-COA DEHYDROGENASE BINARY COMPLEX WITH NADH AND ESTRADIOL
Descriptor:SHORT CHAIN 3-HYDROXYACYL-COA DEHYDROGENASE (E.C.1.1.1.35)
Authors:Read, J.A., Powell, A.J., Brady, R.L.
Deposit date:2000-08-23
Release date:2001-05-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Recognition of Structurally Diverse Substrates by Type II 3-Hydroxyacyl-Coa Dehydrogenase (Hadh II) Amyloid-Beta Binding Alcohol Dehydrogenase (Abad)
J.Mol.Biol., 303, 2000
1EDO
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1edo
THE X-RAY STRUCTURE OF BETA-KETO ACYL CARRIER PROTEIN REDUCTASE FROM BRASSICA NAPUS COMPLEXED WITH NADP+
Descriptor:BETA-KETO ACYL CARRIER PROTEIN REDUCTASE FROM BRASSICA NAPUS COMPLEXED WITH NADP+
Authors:Fisher, M., Kroon, J.T., Martindale, W., Stuitje, A.R., Slabas, A.R., Rafferty, J.B.
Deposit date:2000-01-28
Release date:2001-01-31
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The X-ray structure of Brassica napus beta-keto acyl carrier protein reductase and its implications for substrate binding and catalysis.
Structure Fold.Des., 8, 2000
1EQU
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1equ
TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EQUILIN COMPLEXED WITH NADP+
Descriptor:ESTRADIOL 17 BETA-DEHYDROGENASE 1 (E.C.1.1.1.62)
Authors:Sawicki, M.W., Erman, M., Puranen, T., Vihko, P., Ghosh, D.
Deposit date:1998-12-02
Release date:1999-12-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+.
Proc.Natl.Acad.Sci.USA, 96, 1999
1FDS
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1fds
HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 COMPLEXED WITH 17-BETA-ESTRADIOL
Descriptor:17-BETA-HYDROXYSTEROID-DEHYDROGENASE, ESTRADIOL
Authors:Housset, D., Breton, R., Mazza, C., Fontecilla-Camps, J.-C.
Deposit date:1996-06-28
Release date:1997-02-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors.
Structure, 4, 1996
1FDT
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1fdt
HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 COMPLEXED WITH ESTRADIOL AND NADP+
Descriptor:17-BETA-HYDROXYSTEROID-DEHYDROGENASE, ESTRADIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Housset, D., Breton, R., Mazza, C., Fontecilla-Camps, J.-C.
Deposit date:1996-06-28
Release date:1997-02-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors.
Structure, 4, 1996
1FDU
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1fdu
HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 MUTANT H221L COMPLEXED WITH ESTRADIOL AND NADP+
Descriptor:17-BETA-HYDROXYSTEROID DEHYDROGENASE, ESTRADIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Mazza, C., Breton, R., Housset, D., Fontecilla-Camps, J.-C.
Deposit date:1998-01-14
Release date:1998-05-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Unusual charge stabilization of NADP+ in 17beta-hydroxysteroid dehydrogenase.
J.Biol.Chem., 273, 1998
1FDV
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1fdv
HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 MUTANT H221L COMPLEXED WITH NAD+
Descriptor:17-BETA-HYDROXYSTEROID DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Mazza, C., Breton, R., Housset, D., Fontecilla-Camps, J.-C.
Deposit date:1998-01-15
Release date:1998-05-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Unusual charge stabilization of NADP+ in 17beta-hydroxysteroid dehydrogenase.
J.Biol.Chem., 273, 1998
1FDW
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1fdw
HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 MUTANT H221Q COMPLEXED WITH ESTRADIOL
Descriptor:17-BETA-HYDROXYSTEROID DEHYDROGENASE, ESTRADIOL
Authors:Mazza, C., Breton, R., Housset, D., Fontecilla-Camps, J.-C.
Deposit date:1998-01-16
Release date:1998-05-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Unusual charge stabilization of NADP+ in 17beta-hydroxysteroid dehydrogenase.
J.Biol.Chem., 273, 1998
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