5K1H
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EIF3B RELOCATED TO THE INTERSUBUNIT FACE TO INTERACT WITH EIF1 AND BELOW THE EIF2 TERNARY-COMPLEX. FROM THE STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX IN CLOSED CONFORMATION.
Descriptor:Eukaryotic translation initiation factor 3 subunit B, eIF3a C-terminal tail
Authors:Simonetti, A., Brito Querido, J., Myasnikov, A.G., Mancera-Martinez, E., Renaud, A., Kuhn, L., Hashem, Y.
Deposit date:2016-05-18
Release date:2016-07-13
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition.
Mol.Cell, 2016
5K0Y
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M48S LATE-STAGE INITIATION COMPLEX, PURIFIED FROM RABBIT RETICULOCYTES LYSATES, DISPLAYING EIF2 TERNARY COMPLEX AND EIF3 I AND G SUBUNITS RELOCATED TO THE INTERSUBUNIT FACE
Descriptor:Eukaryotic translation initiation factor 2 subunit 1, ribosomal protein uS17, ribosomal protein uS9, 40S ribosomal protein S4, ribosomal protein uS14, Ribosomal protein S9 (Predicted), ribosomal protein uS13, Eukaryotic translation initiation factor 3 subunit G, ribosomal protein uS12, Uncharacterized protein, eukaryotic initiation factor 2 Gamma subunit (eIF2-Gamma), Eukaryotic translation initiation factor 3 subunit I, ribosomal protein uS7, ribosomal protein eS25, ribosomal protein eS7, 40S ribosomal protein S27, ribosomal protein uS15, ribosomal protein uS8, 40S ribosomal protein S21, ribosomal protein uS5, eukaryotic initiation factor 2 subunit Beta (eIF2-Beta), ribosomal protein eS17, ribosomal protein uS2, ribosomal protein uS3, ribosomal protein uS10, ribosomal protein eS1, ribosomal protein uS11, ribosomal protein eS28, ribosomal protein RACK1, ribosomal protein uS19, 40S ribosomal protein S8, ribosomal protein eS31, 40S ribosomal protein S6, 40S ribosomal protein S12, 40S ribosomal protein S24/RNA Complex
Authors:Simonetti, A., Brito Querido, J., Myasnikov, A.G., Mancera-Martinez, E., Renaud, A., Kuhn, L., Hashem, Y.
Deposit date:2016-05-17
Release date:2016-07-13
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition.
Mol.Cell, 2016
5IQQ
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CRYSTAL STRUCTURE OF THE HUMAN RBM7 RRM DOMAIN
Descriptor:RNA-binding protein 7
Authors:Sofos, N., Winkler, M.B.L., Brodersen, D.E.
Deposit date:2016-03-11
Release date:2016-05-04
Modification date:2016-05-11
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:RRM domain of human RBM7: purification, crystallization and structure determination.
Acta Crystallogr.,Sect.F, 72, 2016
5FJ4
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STRUCTURE OF THE STANDARD KINK TURN HMKT-7 AS STEM LOOP BOUND WITH U1A AND L7AE PROTEINS
Descriptor:U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A, 50S RIBOSOMAL PROTEIN L7AE
Authors:Huang, L., Lilley, D.M.J.
Deposit date:2015-10-06
Release date:2016-05-25
Modification date:2016-07-06
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A Critical Base Pair in K-Turns Determines the Conformational Class Adopted, and Correlates with Biological Function.
Nucleic Acids Res., 44, 2016
5EV4
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STRUCTURE IV OF INTACT U2AF65 RECOGNIZING THE 3' SPLICE SITE SIGNAL
Descriptor:Splicing factor U2AF 65 kDa subunit/DNA Complex
Authors:Agrawal, A.A., Jenkins, J.L., Kielkopf, C.L.
Deposit date:2015-11-19
Release date:2016-02-24
Modification date:2016-03-23
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.
Nat Commun, 7, 2016
5EV3
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STRUCTURE III OF INTACT U2AF65 RECOGNIZING THE 3' SPLICE SITE SIGNAL
Descriptor:Splicing factor U2AF 65 kDa subunit/DNA Complex
Authors:Agrawal, A.A., Jenkins, J.L., Kielkopf, C.L.
Deposit date:2015-11-19
Release date:2016-02-24
Modification date:2016-03-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.
Nat Commun, 7, 2016
5EV2
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STRUCTURE II OF INTACT U2AF65 RECOGNIZING THE 3' SPLICE SITE SIGNAL
Descriptor:Splicing factor U2AF 65 kDa subunit
Authors:Agrawal, A.A., Jenkins, J.L., Kielkopf, C.L.
Deposit date:2015-11-19
Release date:2016-02-24
Modification date:2016-03-23
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.
Nat Commun, 7, 2016
5EV1
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STRUCTURE I OF INTACT U2AF65 RECOGNIZING A 3' SPLICE SITE SIGNAL
Descriptor:Splicing factor U2AF 65 kDa subunit/RNA Complex
Authors:Agrawal, A.A., Jenkins, J.L., Kielkopf, C.L.
Deposit date:2015-11-19
Release date:2016-02-24
Modification date:2016-03-23
Method:X-RAY DIFFRACTION (2.037 Å)
Cite:An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.
Nat Commun, 7, 2016
5DET
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X-RAY STRUCTURE OF HUMAN RBPMS IN COMPLEX WITH THE RNA
Descriptor:RNA-binding protein with multiple splicing/RNA Complex
Authors:Teplova, M., Farazi, T.A., Tuschl, T., Patel, D.J.
Deposit date:2015-08-25
Release date:2015-09-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS.
Q. Rev. Biophys., 2015
5DDR
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L-GLUTAMINE RIBOSWITCH BOUND WITH L-GLUTAMINE SOAKED WITH CS+
Descriptor:U1 small nuclear ribonucleoprotein A/RNA Complex
Authors:Ren, A., Patel, D.J.
Deposit date:2015-08-25
Release date:2015-12-23
Method:X-RAY DIFFRACTION (2.605 Å)
Cite:Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
5DDQ
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L-GLUTAMINE RIBOSWITCH BOUND WITH L-GLUTAMINE SOAKED WITH MN2+
Descriptor:U1 small nuclear ribonucleoprotein A/RNA Complex
Authors:Ren, A., Patel, D.J.
Deposit date:2015-08-25
Release date:2015-12-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
5DDP
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L-GLUTAMINE RIBOSWITCH BOUND WITH L-GLUTAMINE
Descriptor:U1 small nuclear ribonucleoprotein A/RNA Complex
Authors:Ren, A., Patel, D.J.
Deposit date:2015-08-25
Release date:2015-12-23
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
5DDO
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STRUCTURAL AND DYNAMIC BASIS FOR LOW AFFINITY-HIGH SELECTIVITY BINDING OF L-GLUTAMINE BY THE GLN-RIBOSWITCH
Descriptor:U1 small nuclear ribonucleoprotein A/RNA Complex
Authors:Ren, A., Patel, D.
Deposit date:2015-08-25
Release date:2015-12-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
5CYJ
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X-RAY STRUCTURE OF HUMAN RBPMS
Descriptor:RNA-binding protein with multiple splicing
Authors:Teplova, M., Farazi, T.A., Patel, D.J.
Deposit date:2015-07-30
Release date:2015-09-30
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS.
Q. Rev. Biophys., 2015
5CA5
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STRUCTURE OF THE C. ELEGANS NONO-1 HOMODIMER
Descriptor:NONO-1
Authors:Knott, G.J., Bond, C.S.
Deposit date:2015-06-29
Release date:2015-12-09
Modification date:2016-01-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Caenorhabditis elegans NONO-1: Insights into DBHS protein structure, architecture, and function.
Protein Sci., 24, 2015
5A5U
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STRUCTURE OF MAMMALIAN EIF3 IN THE CONTEXT OF THE 43S PREINITIATION COMPLEX
Descriptor:EUKARYOTIC INITIATION FACTOR 3, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I
Authors:des-Georges, A., Dhote, V., Kuhn, L., Hellen, C.U.T., Pestova, T.V., Frank, J., Hashem, Y.
Deposit date:2015-06-21
Release date:2015-09-09
Modification date:2015-09-30
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structure of Mammalian Eif3 in the Context of the 43S Preinitiation Complex.
Nature, 525, 2015
4ZKA
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HIGH RESOLUTION CRYSTAL STRUCTURE OF FOX1 RRM
Descriptor:RNA binding protein fox-1 homolog 1
Authors:Blatter, M., Allain, F.H.-T.
Deposit date:2015-04-30
Release date:2016-06-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High Resolution Crystal Structure of Fox1 RRM
To Be Published
4Z2X
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CRYSTAL STRUCTURE OF A RNA BINDING DOMAIN OF A U2 SMALL NUCLEAR RIBONUCLEOPROTEIN AUXILIARY FACTOR 2 (U2AF) FROM MOUSE AT 2.15 A RESOLUTION
Descriptor:RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2015-03-30
Release date:2015-04-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from mouse at 2.15 A resolution
To be published
4YUD
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CRYSTAL STRUCTURE OF A RNA BINDING MOTIF PROTEIN 39 (RBM39) FROM HOMO SAPIENS AT 1.28 A RESOLUTION
Descriptor:RNA binding motif protein 39
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2015-03-18
Release date:2015-04-01
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Crystal structure of a RNA binding motif protein 39 (RBM39) from Homo sapiens at 1.28 A resolution
To be published
4YOE
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STRUCTURE OF UP1 BOUND TO RNA 5'-AGU-3'
Descriptor:UP1/RNA Complex
Authors:Meagher, J.L., Stuckey, J.A.
Deposit date:2015-03-11
Release date:2015-06-10
Modification date:2015-10-07
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA Reveals a New Look for an Old RNA Binding Protein.
J.Mol.Biol., 427, 2015
4YH8
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STRUCTURE OF YEAST U2AF COMPLEX
Descriptor:Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit
Authors:Yoshida, H., Park, S.Y., Urano, T., Obayashi, E.
Deposit date:2015-02-27
Release date:2015-08-12
Modification date:2015-08-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit.
Genes Dev., 29, 2015
4YB1
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20A MUTANT C-DI-GMP VC2 RIBOSWITCH BOUND WITH 3',3'-CGAMP
Descriptor:U1 small nuclear ribonucleoprotein A/RNA Complex
Authors:Ren, A.M., Patel, D.J., Rajashankar, R.K.
Deposit date:2015-02-18
Release date:2015-04-15
Modification date:2015-07-22
Method:X-RAY DIFFRACTION (2.081 Å)
Cite:Structural Basis for Molecular Discrimination by a 3',3'-cGAMP Sensing Riboswitch.
Cell Rep, 11, 2015
4Y0F
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CRYSTAL STRUCTURE OF HUMAN TDP-43 RRM1 DOMAIN IN COMPLEX WITH AN UNMODIFIED SINGLE-STRANDED DNA
Descriptor:TAR DNA-binding protein 43/DNA
Authors:Chiang, C.H., Kuo, P.H., Doudeva, L.G., Wang, Y.T., Yuan, H.S.
Deposit date:2015-02-06
Release date:2016-02-10
Modification date:2016-03-09
Method:X-RAY DIFFRACTION (2.648 Å)
Cite:Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation
Sci Rep, 6, 2016
4Y00
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CRYSTAL STRUCTURE OF HUMAN TDP-43 RRM1 DOMAIN WITH D169G MUTATION IN COMPLEX WITH AN UNMODIFIED SINGLE-STRANDED DNA
Descriptor:TDP-43 RRM1-D169G/DNA Complex
Authors:Chiang, C.H., Kuo, P.H., Yang, W.Z., Yuan, H.S.
Deposit date:2015-02-05
Release date:2016-02-10
Modification date:2016-03-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation
Sci Rep, 6, 2016
4WKR
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LARP7 WRAPPING UP THE 3' HAIRPIN OF 7SK NON-CODING RNA (302-332)
Descriptor:HUMAN LARP7/RNA Complex
Authors:Uchikawa, E., Natchiar, K.S., Han, X., Proux, F., Roblin, P., Zhang, E., Durand, A., Klaholz, B.P., Dock-Bregeon, A.-C.
Deposit date:2014-10-03
Release date:2015-03-18
Modification date:2015-04-15
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7.
Nucleic Acids Res., 43, 2015
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