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121P
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121p
STRUKTUR UND GUANOSINTRIPHOSPHAT-HYDROLYSEMECHANISMUS DES C-TERMINAL VERKUERZTEN MENSCHLICHEN KREBSPROTEINS P21-H-RAS
Descriptor:H-RAS P21 PROTEIN COMPLEX WITH GUANOSINE-5'-[B,G-METHYLENE] TRIPHOSPHATE
Authors:Krengel, U., Scheffzek, K., Scherer, A., Kabsch, W., Wittinghofer, A., Pai, E.F.
Deposit date:1991-06-06
Release date:1994-01-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Struktur Und Guanosintriphosphat-Hydrolysemechanismus Des C-Terminal Verkuerzten Menschlichen Krebsproteins P21-H-Ras
Thesis, 1991
1A2B
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1a2b
HUMAN RHOA COMPLEXED WITH GTP ANALOGUE
Descriptor:TRANSFORMING PROTEIN RHOA, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE
Authors:Ihara, K., Muraguchi, S., Kato, M., Shimizu, T., Shirakawa, M., Kuroda, S., Kaibuchi, K., Hakoshima, T.
Deposit date:1997-12-26
Release date:1998-06-17
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue.
J.Biol.Chem., 273, 1998
1A4R
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1a4r
G12V MUTANT OF HUMAN PLACENTAL CDC42 GTPASE IN THE GDP FORM
Descriptor:G25K GTP-BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE, AMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Rudolph, M.G., Vetter, I.R., Wittinghofer, A.
Deposit date:1998-02-02
Release date:1999-03-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: two different nucleotide states in one crystal.
Protein Sci., 8, 1999
1AA9
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1aa9
HUMAN C-HA-RAS(1-171)(DOT)GDP, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:C-HA-RAS, GUANOSINE-5'-DIPHOSPHATE
Authors:Ito, Y., Yamasaki, Y., Muto, Y., Kawai, G., Nishimura, S., Miyazawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1997-01-27
Release date:1997-07-29
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Regional polysterism in the GTP-bound form of the human c-Ha-Ras protein.
Biochemistry, 36, 1997
1AGP
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1agp
THREE-DIMENSIONAL STRUCTURES AND PROPERTIES OF A TRANSFORMING AND A NONTRANSFORMING GLY-12 MUTANT OF P21-H-RAS
Descriptor:C-H-RAS P21 PROTEIN MUTANT WITH GLY 12 REPLACED BY ASP (G12D) COMPLEXED WITH GUANOSINE-5'-[B,G-IMIDO] TRIPHOSPHATE
Authors:Franken, S.M., Scheidig, A.J., Wittinghofer, A., Goody, R.S.
Deposit date:1993-03-29
Release date:1994-04-30
Modification date:2012-03-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras.
Biochemistry, 32, 1993
1AJE
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1aje
CDC42 FROM HUMAN, NMR, 20 STRUCTURES
Descriptor:CDC42HS
Authors:Feltham, J.L., Dotsch, V., Raza, S., Manor, D., Cerione, R.A., Sutcliffe, M.J., Wagner, G., Oswald, R.E.
Deposit date:1997-05-02
Release date:1997-11-12
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Definition of the switch surface in the solution structure of Cdc42Hs.
Biochemistry, 36, 1997
1AN0
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1an0
CDC42HS-GDP COMPLEX
Descriptor:CDC42HS-GDP, GUANOSINE-5'-DIPHOSPHATE
Authors:Kongsaeree, P., Cerione, R., Clardy, J.
Deposit date:1997-06-26
Release date:1999-01-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure Determination of Cdc42Hs and Gdp Complex
To be Published
1BYU
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1byu
CANINE GDP-RAN
Descriptor:PROTEIN (RAN)
Authors:Stewart, M., Kent, H.M., Mccoy, A.J.
Deposit date:1998-10-18
Release date:1998-12-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2).
J.Mol.Biol., 284, 1998
1CF4
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1cf4
CDC42/ACK GTPASE-BINDING DOMAIN COMPLEX
Descriptor:CDC42 HOMOLOG, ACTIVATED P21CDC42HS KINASE
Authors:Mott, H.R., Owen, D., Nietlispach, D., Lowe, P.N., Lim, L., Laue, E.D.
Deposit date:1999-03-23
Release date:1999-06-18
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK.
Nature, 399, 1999
1CLU
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1clu
H-RAS COMPLEXED WITH DIAMINOBENZOPHENONE-BETA,GAMMA-IMIDO-GTP
Descriptor:TRANSFORMING PROTEIN P21/H-RAS-1
Authors:Ahmadian, M.R., Zor, T., Vogt, D., Kabsch, W., Selinger, Z., Wittinghofer, A., Scheffzek, K.
Deposit date:1999-05-03
Release date:1999-05-28
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Guanosine triphosphatase stimulation of oncogenic Ras mutants.
Proc.Natl.Acad.Sci.USA, 96, 1999
1CRP
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1crp
THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY
Descriptor:C-H-RAS P21 PROTEIN (CATALYTIC DOMAIN, RESIDUES 1 - 166) COMPLEXED WITH GDP AND MG (NMR, FIRST 20 STRUCTURES)
Authors:Kraulis, P.J., Domaille, P.J., Campbell-Burk, S.L., Van Aken, T., Laue, E.D.
Deposit date:1993-11-24
Release date:1994-07-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy.
Biochemistry, 33, 1994
1CRQ
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1crq
THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY
Descriptor:C-H-RAS P21 PROTEIN (CATALYTIC DOMAIN, RESIDUES 1 - 166) COMPLEXED WITH GDP AND MG (NMR, RESTRAINED MINIMIZED AVERAGE)
Authors:Kraulis, P.J., Domaille, P.J., Campbell-Burk, S.L., Van Aken, T., Laue, E.D.
Deposit date:1993-11-24
Release date:1994-07-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy.
Biochemistry, 33, 1994
1CRR
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1crr
THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY
Descriptor:C-H-RAS P21 PROTEIN (CATALYTIC DOMAIN, RESIDUES 1 - 166) COMPLEXED WITH GDP AND MG (NMR, FINAL 20 STRUCTURES)
Authors:Kraulis, P.J., Domaille, P.J., Campbell-Burk, S.L., Van Aken, T., Laue, E.D.
Deposit date:1993-11-24
Release date:1994-07-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy.
Biochemistry, 33, 1994
1CTQ
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1ctq
STRUCTURE OF P21RAS IN COMPLEX WITH GPPNHP AT 100 K
Descriptor:PROTEIN (TRANSFORMING PROTEIN P21/H-RAS-1)
Authors:Scheidig, A., Burmester, C., Goody, R.S.
Deposit date:1999-08-20
Release date:1999-11-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:The pre-hydrolysis state of p21(ras) in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins.
Structure Fold.Des., 7, 1999
1D5C
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1d5c
CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM RAB6 COMPLEXED WITH GDP
Descriptor:RAB6 GTPASE
Authors:Chattopadhyay, D., Langsley, G., Carson, M., Recacha, R., DeLucas, L., Smith, C.
Deposit date:1999-10-06
Release date:2000-08-30
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the nucleotide-binding domain of Plasmodium falciparum rab6 in the GDP-bound form.
Acta Crystallogr.,Sect.D, 56, 2000
1DPF
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1dpf
CRYSTAL STRUCTURE OF A MG-FREE FORM OF RHOA COMPLEXED WITH GDP
Descriptor:CRYSTAL STRUCTURE OF A MG-FREE FORM OF RHOA COMPLEXED WITH GDP
Authors:Shimizu, T., Ihara, K., Maesaki, R., Kuroda, S., Kaibuchi, K., Hakoshima, T.
Deposit date:1999-12-27
Release date:2000-06-21
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism.
J.Biol.Chem., 275, 2000
1EK0
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1ek0
GPPNHP-BOUND YPT51 AT 1.48 A RESOLUTION
Descriptor:GTP-BINDING PROTEIN YPT51
Authors:Esters, H., Scheidig, A.J.
Deposit date:2000-03-06
Release date:2000-04-17
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:High-resolution crystal structure of S. cerevisiae Ypt51(DeltaC15)-GppNHp, a small GTP-binding protein involved in regulation of endocytosis.
J.Mol.Biol., 298, 2000
1FTN
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1ftn
CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX
Descriptor:TRANSFORMING PROTEIN RHOA (H12), GUANOSINE-5'-DIPHOSPHATE
Authors:Wei, Y., Zhang, Y., Derewenda, U., Liu, X., Minor, W., Nakamoto, R.K., Somlyo, A.V., Somlyo, A.P., Derewenda, Z.S.
Deposit date:1997-03-13
Release date:1998-03-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of RhoA-GDP and its functional implications.
Nat.Struct.Biol., 4, 1997
1G16
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1g16
CRYSTAL STRUCTURE OF SEC4-GDP
Descriptor:RAS-RELATED PROTEIN SEC4
Authors:Stroupe, C., Brunger, A.T.
Deposit date:2000-10-10
Release date:2000-12-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of a Rab protein in its inactive and active conformations.
J.Mol.Biol., 304, 2000
1G17
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1g17
CRYSTAL STRUCTURE OF SEC4-GUANOSINE-5'-(BETA,GAMMA)-IMIDOTRIPHOSPHATE
Descriptor:RAS-RELATED PROTEIN SEC4
Authors:Stroupe, C., Brunger, A.T.
Deposit date:2000-10-10
Release date:2000-12-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of a Rab protein in its inactive and active conformations.
J.Mol.Biol., 304, 2000
1GNP
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1gnp
X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND MANT DGPPNHP
Descriptor:C-H-RAS P21 PROTEIN COMPLEXED WITH 3'-O-(N-METHYL-ANTHRANILOYL-2'-DEOXYGUANOSINE-5'-[BETA,GAMMA-IMIDO]-TRIPHOSPHATE (RESIDUES 1 - 166)
Authors:Scheidig, A., Franken, S.M., Corrie, J.E.T., Reid, G.P., Wittinghofer, A., Pai, E.F., Goody, R.S.
Deposit date:1995-05-11
Release date:1995-07-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray crystal structure analysis of the catalytic domain of the oncogene product p21H-ras complexed with caged GTP and mant dGppNHp.
J.Mol.Biol., 253, 1995
1GNQ
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1gnq
X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND MANT DGPPNHP
Descriptor:C-H-RAS P21 PROTEIN COMPLEXED WITH P3-1[S]-(2-NITROPHENYL)-ETHYL-GUANOSINE-5'-TRIPHOSPHATE (S-DIASTEREOMER) (RESIDUES 1 - 166)
Authors:Scheidig, A., Franken, S.M., Corrie, J.E.T., Reid, G.P., Wittinghofer, A., Pai, E.F., Goody, R.S.
Deposit date:1995-05-11
Release date:1995-07-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray crystal structure analysis of the catalytic domain of the oncogene product p21H-ras complexed with caged GTP and mant dGppNHp.
J.Mol.Biol., 253, 1995
1GNR
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1gnr
X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND MANT DGPPNHP
Descriptor:C-H-RAS P21 PROTEIN COMPLEXED WITH P3-1[R]-(2-NITROPHENYL)-ETHYL-GUANOSINE-5'-TRIPHOSPHATE (R-DIASTEREOMER) (RESIDUES 1 - 166)
Authors:Scheidig, A., Franken, S.M., Corrie, J.E.T., Reid, G.P., Wittinghofer, A., Pai, E.F., Goody, R.S.
Deposit date:1995-05-11
Release date:1995-07-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-ray crystal structure analysis of the catalytic domain of the oncogene product p21H-ras complexed with caged GTP and mant dGppNHp.
J.Mol.Biol., 253, 1995
1GWN
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1gwn
THE CRYSTAL STRUCTURE OF THE CORE DOMAIN OF RHOE/RND3 - A CONSTITUTIVELY ACTIVATED SMALL G PROTEIN
Descriptor:RHO-RELATED GTP-BINDING PROTEIN RHOE
Authors:Garavini, H., Riento, K., Phelan, J.P., Mcalister, M.S.B., Ridley, A.J., Keep, N.H.
Deposit date:2002-03-19
Release date:2002-04-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the Core Domain of Rhoe/Rnd3: A Constitutively Activated Small G Protein
Biochemistry, 41, 2002
1HUQ
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1huq
1.8A CRYSTAL STRUCTURE OF THE MONOMERIC GTPASE RAB5C (MOUSE)
Descriptor:RAB5C
Authors:Merithew, E., Hatherly, S., Dumas, J.J., Lawe, D.C., Heller-Harrison, R., Lambright, D.G.
Deposit date:2001-01-04
Release date:2001-02-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition.
J.Biol.Chem., 276, 2001
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