2CE2
  • Download 2ce2
  • View 2ce2
Molmil generated image of 2ce2
CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GDP
Descriptor:GTPASE HRAS
Authors:Klink, B.U., Goody, R.S., Scheidig, A.J.
Deposit date:2006-02-02
Release date:2006-08-23
Modification date:2015-04-22
Method:X-RAY DIFFRACTION (1 Å)
Cite:A Newly Designed Microspectrofluorometer for Kinetic Studies on Protein Crystals in Combination with X-Ray Diffraction
Biophys.J., 91, 2006
3X1X
  • Download 3x1x
  • View 3x1x
Molmil generated image of 3x1x
RAS-RELATED PROTEIN RAP1B WITH GPPNHP
Descriptor:Ras-related protein Rap-1b
Authors:Noguchi, H., Ikegami, T., Park, S.Y., Tame, J.R.H., Unzai, S.
Deposit date:2014-12-02
Release date:2015-06-03
Method:X-RAY DIFFRACTION (1 Å)
Cite:The structure and conformational switching of Rap1B
Biochem.Biophys.Res.Commun., 462, 2015
4QL3
  • Download 4ql3
  • View 4ql3
Molmil generated image of 4ql3
CRYSTAL STRUCTURE OF A GDP-BOUND G12R ONCOGENIC MUTANT OF HUMAN GTPASE KRAS
Descriptor:GTPase KRas (E.C.3.6.5.2)
Authors:Hunter, J.C., Manandhar, A., Gurbani, D., Chen, Z., Westover, K.D.
Deposit date:2014-06-10
Release date:2015-06-10
Modification date:2015-09-30
Method:X-RAY DIFFRACTION (1.041 Å)
Cite:Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations.
Mol Cancer Res., 13, 2015
1R2Q
  • Download 1r2q
  • View 1r2q
Molmil generated image of 1r2q
CRYSTAL STRUCTURE OF HUMAN RAB5A GTPASE DOMAIN AT 1.05 A RESOLUTION
Descriptor:Ras-related protein Rab-5A
Authors:Terzyan, S., Zhu, G., Li, G., Zhang, X.C.
Deposit date:2003-09-29
Release date:2003-12-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Refinement of the structure of human Rab5a GTPase domain at 1.05 A resolution.
Acta Crystallogr.,Sect.D, 60, 2004
2EVW
  • Download 2evw
  • View 2evw
Molmil generated image of 2evw
CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH R-CAGED GTP
Descriptor:GTPase HRas
Authors:Klink, B.U.
Deposit date:2005-11-01
Release date:2006-05-30
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:A newly designed microspectrofluorometer for kinetic studies on protein crystals in combination with x-ray diffraction.
Biophys.J., 91, 2006
2HXS
  • Download 2hxs
  • View 2hxs
Molmil generated image of 2hxs
CRYSTAL STRUCTURE OF RAB28A GTPASE IN THE INACTIVE (GDP-3'P-BOUND) FORM
Descriptor:Ras-related protein Rab-28
Authors:Lee, S.H., Li, Y., Dominguez, R.
Deposit date:2006-08-03
Release date:2007-08-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Crystal Structure of Rab28 GTPase in Active and Inactive Forms
To be Published
4TQA
  • Download 4tqa
  • View 4tqa
Molmil generated image of 4tqa
CRYSTAL STRUCTURE OF A GDP-BOUND G13D ONCOGENIC MUTANT OF HUMAN GTPASE KRAS
Descriptor:GTPase KRas
Authors:Hunter, J.C., Manandhar, A., Gurbani, D., Chen, Z., Westover, K.D.
Deposit date:2014-06-10
Release date:2015-06-10
Modification date:2015-09-30
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations.
Mol Cancer Res., 13, 2015
4LDJ
  • Download 4ldj
  • View 4ldj
Molmil generated image of 4ldj
CRYSTAL STRUCTURE OF A GDP-BOUND G12C ONCOGENIC MUTANT OF HUMAN GTPASE KRAS
Descriptor:GTPase KRas
Authors:Hunter, J.C., Gurbani, D., Chen, Z., Westover, K.D.
Deposit date:2013-06-24
Release date:2014-06-04
Modification date:2014-07-09
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C.
Proc.Natl.Acad.Sci.USA, 111, 2014
3X1Y
  • Download 3x1y
  • View 3x1y
Molmil generated image of 3x1y
RAS-RELATED PROTEIN RAP1B(L9V) WITH GPPNHP
Descriptor:Ras-related protein Rap-1b
Authors:Noguchi, H., Ikegami, T., Park, S.Y., Tame, J.R.H., Unzai, S.
Deposit date:2014-12-02
Release date:2015-06-03
Method:X-RAY DIFFRACTION (1.168 Å)
Cite:The structure and conformational switching of Rap1B
Biochem.Biophys.Res.Commun., 462, 2015
3KKQ
  • Download 3kkq
  • View 3kkq
Molmil generated image of 3kkq
CRYSTAL STRUCTURE OF M-RAS P40D IN COMPLEX WITH GDP
Descriptor:Ras-related protein M-Ras
Authors:Muraoka, S., Shima, F., Liao, J., Ijiri, Y., Matsumoto, K., Ye, M., Inoue, T., Kataoka, T.
Deposit date:2009-11-06
Release date:2010-06-16
Modification date:2014-02-12
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural basis for conformational dynamics of GTP-bound Ras protein
J.Biol.Chem., 285, 2010
3X1W
  • Download 3x1w
  • View 3x1w
Molmil generated image of 3x1w
RAS-RELATED PROTEIN RAP1B WITH GDP
Descriptor:Ras-related protein Rap-1b
Authors:Noguchi, H., Ikegami, T., Akashi, S., Park, S.Y., Tame, J.R.H., Unzai, S.
Deposit date:2014-12-02
Release date:2015-06-03
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The structure and conformational switching of Rap1B
Biochem.Biophys.Res.Commun., 462, 2015
4Q03
  • Download 4q03
  • View 4q03
Molmil generated image of 4q03
SECOND-SITE SCREENING OF K-RAS IN THE PRESENCE OF COVALENTLY ATTACHED FIRST-SITE LIGANDS
Descriptor:GTPase KRas (E.C.3.6.5.2)
Authors:Sun, Q., Phan, J., Friberg, A., Camper, D.V., Olejniczak, E.T., Fesik, S.W.
Deposit date:2014-03-31
Release date:2014-09-10
Method:X-RAY DIFFRACTION (1.201 Å)
Cite:A method for the second-site screening of K-Ras in the presence of a covalently attached first-site ligand.
J.Biomol.Nmr, 60, 2014
2CLD
  • Download 2cld
  • View 2cld
Molmil generated image of 2cld
CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GDP (2)
Descriptor:GTPASE HRAS
Authors:Klink, B.U., Goody, R.S., Scheidig, A.J.
Deposit date:2006-04-27
Release date:2006-05-31
Modification date:2015-04-22
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:A Newly Designed Microspectrofluorometer for Kinetic Studies on Protein Crystals in Combination with X-Ray Diffraction
Biophys.J., 91, 2006
2CL6
  • Download 2cl6
  • View 2cl6
Molmil generated image of 2cl6
CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH S-CAGED GTP
Descriptor:GTPASE HRAS
Authors:Klink, B.U., Goody, R.S., Scheidig, A.J.
Deposit date:2006-04-26
Release date:2006-05-24
Modification date:2015-04-22
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:A Newly Designed Microspectrofluorometer for Kinetic Studies on Protein Crystals in Combination with X-Ray Diffraction.
Biophys.J., 91, 2006
4OBE
  • Download 4obe
  • View 4obe
Molmil generated image of 4obe
CRYSTAL STRUCTURE OF GDP-BOUND HUMAN KRAS
Descriptor:GTPase KRas (E.C.3.6.5.2)
Authors:Hunter, J.C., Gurbani, D., Chen, Z., Westover, K.D.
Deposit date:2014-01-07
Release date:2014-06-04
Modification date:2014-07-09
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C.
Proc.Natl.Acad.Sci.USA, 111, 2014
1WMS
  • Download 1wms
  • View 1wms
Molmil generated image of 1wms
HIGH RESOLUTION CRYSTAL STRUCTURE OF HUMAN RAB9 GTPASE: A NOVEL ANTIVIRAL DRUG TARGET
Descriptor:Ras-related protein Rab-9A
Authors:Chen, L., DiGiammarino, E., Zhou, X.E., Wang, Y., Toh, D., Hodge, T.W., Meehan, E.J.
Deposit date:2004-07-16
Release date:2004-09-14
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:High resolution crystal structure of human Rab9 GTPase: A novel antiviral drug target
J.Biol.Chem., 279, 2004
2CL7
  • Download 2cl7
  • View 2cl7
Molmil generated image of 2cl7
CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GTP
Descriptor:GTPASE HRAS
Authors:Klink, B.U., Goody, R.S., Scheidig, A.J.
Deposit date:2006-04-26
Release date:2006-05-24
Modification date:2015-04-22
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A Newly Designed Microspectrofluorometer for Kinetic Studies on Protein Crystals in Combination with X-Ray Diffraction.
Biophys.J., 91, 2006
3X1Z
  • Download 3x1z
  • View 3x1z
Molmil generated image of 3x1z
RAS-RELATED PROTEIN RAP1B(T65A) WITH GPPNHP
Descriptor:Ras-related protein Rap-1b
Authors:Noguchi, H., Ikegami, T., Park, S.Y., Tame, J.R.H., Unzai, S.
Deposit date:2014-12-02
Release date:2015-06-03
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The structure and conformational switching of Rap1B
Biochem.Biophys.Res.Commun., 462, 2015
1CTQ
  • Download 1ctq
  • View 1ctq
Molmil generated image of 1ctq
STRUCTURE OF P21RAS IN COMPLEX WITH GPPNHP AT 100 K
Descriptor:PROTEIN (TRANSFORMING PROTEIN P21/H-RAS-1)
Authors:Scheidig, A., Burmester, C., Goody, R.S.
Deposit date:1999-08-20
Release date:1999-11-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:The pre-hydrolysis state of p21(ras) in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins.
Structure Fold.Des., 7, 1999
4LUC
  • Download 4luc
  • View 4luc
Molmil generated image of 4luc
CRYSTAL STRUCTURE OF SMALL MOLECULE DISULFIDE 6 BOUND TO K-RAS G12C
Descriptor:GTPase KRas
Authors:Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.
Deposit date:2013-07-25
Release date:2013-11-27
Modification date:2013-12-18
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4Q01
  • Download 4q01
  • View 4q01
Molmil generated image of 4q01
SECOND-SITE SCREENING OF K-RAS IN THE PRESENCE OF COVALENTLY ATTACHED FIRST-SITE LIGANDS
Descriptor:K-Ras (E.C.3.6.5.2)
Authors:Sun, Q., Phan, J., Friberg, A., Camper, D.V., Olejniczak, E.T., Fesik, S.W.
Deposit date:2014-03-31
Release date:2014-09-10
Method:X-RAY DIFFRACTION (1.291 Å)
Cite:A method for the second-site screening of K-Ras in the presence of a covalently attached first-site ligand.
J.Biomol.Nmr, 60, 2014
1X1R
  • Download 1x1r
  • View 1x1r
Molmil generated image of 1x1r
CRYSTAL STRUCTURE OF M-RAS IN COMPLEX WITH GDP
Descriptor:Ras-related protein M-Ras
Authors:Ye, M., Shima, F., Muraoka, S., Liao, J., Okamoto, H., Yamamoto, M., Tamura, A., Yagi, N., Ueki, T., Kataoka, T.
Deposit date:2005-04-12
Release date:2005-07-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structure of M-Ras Reveals a GTP-bound "Off" State Conformation of Ras Family Small GTPases
J.Biol.Chem., 280, 2005
2CLC
  • Download 2clc
  • View 2clc
Molmil generated image of 2clc
CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GTP (2)
Descriptor:GTPASE HRAS
Authors:Klink, B.U., Goody, R.S., Scheidig, A.J.
Deposit date:2006-04-27
Release date:2006-05-24
Modification date:2015-04-22
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:A Newly Designed Microspectrofluorometer for Kinetic Studies on Protein Crystals in Combination with X-Ray Diffraction
Biophys.J., 91, 2006
3K8Y
  • Download 3k8y
  • View 3k8y
Molmil generated image of 3k8y
ALLOSTERIC MODULATION OF H-RAS GTPASE
Descriptor:GTPase HRas
Authors:Holzapfel, G., Buhrman, G., Mattos, C.
Deposit date:2009-10-15
Release date:2010-03-02
Modification date:2010-05-12
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Allosteric modulation of Ras positions Q61 for a direct role in catalysis.
Proc.Natl.Acad.Sci.USA, 107, 2010
3OIW
  • Download 3oiw
  • View 3oiw
Molmil generated image of 3oiw
H-RASG12V WITH ALLOSTERIC SWITCH IN THE "ON" STATE
Descriptor:GTPase HRas
Authors:Kumar, S., Buhrman, G., Mattos, C.
Deposit date:2010-08-20
Release date:2010-12-08
Modification date:2011-02-16
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase.
J.Biol.Chem., 286, 2011
PDBj@FacebookPDBj@TwitterwwPDBwwPDB FoundationEM DataBank

Copyright © 2013-2017 Protein Data Bank Japan