5A0F

Crystal structure of Yersinia Afp18-modified RhoA

Summary for 5A0F

Entry DOI	10.2210/pdb5a0f/pdb
Descriptor	TRANSFORMING PROTEIN RHOA, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, ... (5 entities in total)
Functional Keywords	signaling protein, n-acetylglucosamine-protein, tyrosine glycosylation, gtpase, bacterial toxin effector, type 6 secretion system, antifeeding prophage
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	21227.93
Authors	Jank, T.,Schimpl, M.,van Aalten, D.M. (deposition date: 2015-04-20, release date: 2015-07-22, Last modification date: 2024-01-10)
Primary citation	Jank, T.,Eckerle, S.,Steinemann, M.,Trillhaase, C.,Schimpl, M.,Wiese, S.,van Aalten, D.M.,Driever, W.,Aktories, K. Tyrosine glycosylation of Rho by Yersinia toxin impairs blastomere cell behaviour in zebrafish embryos. Nat Commun, 6:7807-7807, 2015 Cited by PubMed: 26190758 DOI: 10.1038/ncomms8807 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation