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1B2I
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1b2i
KRINGLE 2 DOMAIN OF HUMAN PLASMINOGEN: NMR SOLUTION STRUCTURE OF TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID (AMCHA) COMPLEX
Descriptor:PLASMINOGEN (E.C.3.4.21.7) MUTANT (C181T, E182S, C188G)
Authors:Marti, D.N., Schaller, J., Llinas, M.
Deposit date:1999-09-24
Release date:1999-11-19
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure and dynamics of the plasminogen kringle 2-AMCHA complex: 3(1)-helix in homologous domains.
Biochemistry, 38, 1999
1CEA
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1cea
THE STRUCTURE OF THE NON-COVALENT COMPLEX OF RECOMBINANT KRINGLE 1 DOMAIN OF HUMAN PLASMINOGEN WITH EACA (EPSILON-AMINOCAPROIC ACID)
Descriptor:PLASMINOGEN, 6-AMINOHEXANOIC ACID
Authors:Tulinsky, A., Mathews, I.I.
Deposit date:1995-12-03
Release date:1996-04-03
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexane-1-carboxylic Acid.
Biochemistry, 35, 1996
1CEB
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1ceb
THE STRUCTURE OF THE NON-COVALENT COMPLEX OF RECOMBINANT KRINGLE 1 DOMAIN OF HUMAN PLASMINOGEN WITH AMCHA (TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID)
Descriptor:PLASMINOGEN, TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID
Authors:Tulinsky, A., Mathews, I.I.
Deposit date:1995-12-03
Release date:1996-04-03
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexane-1-carboxylic Acid.
Biochemistry, 35, 1996
1HPJ
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1hpj
SOLUTION NMR STRUCTURE OF THE HUMAN PLASMINOGEN KRINGLE 1 DOMAIN COMPLEXED WITH 6-AMINOHEXANOIC ACID AT PH 5.3, 310K, DERIVED FROM RANDOMLY GENERATED STRUCTURES USING SIMULATED ANNEALING, 12 STRUCTURES
Descriptor:PLASMINOGEN
Authors:Rejante, M., Llinas, M.
Deposit date:1996-08-14
Release date:1997-03-12
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the epsilon-aminohexanoic acid complex of human plasminogen kringle 1.
Eur.J.Biochem., 221, 1994
1HPK
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1hpk
SOLUTION NMR STRUCTURE OF THE HUMAN PLASMINOGEN KRINGLE 1 DOMAIN COMPLEXED WITH 6-AMINOHEXANOIC ACID AT PH 5.3, 310K, DERIVED FROM RANDOMLY GENERATED STRUCTURES USING SIMULATED ANNEALING, MINIMIZED AVERAGE STRUCTURE
Descriptor:PLASMINOGEN, 6-AMINOHEXANOIC ACID
Authors:Rejante, M., Llinas, M.
Deposit date:1996-08-14
Release date:1997-03-12
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the epsilon-aminohexanoic acid complex of human plasminogen kringle 1.
Eur.J.Biochem., 221, 1994
1I71
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1i71
HIGH RESOLUTION CRYSTAL STRUCTURE OF APOLIPOPROTEIN(A) KRINGLE IV TYPE 7: INSIGHTS INTO LIGAND BINDING
Descriptor:APOLIPOPROTEIN(A) (E.C.3.4.21.-)
Authors:Ye, Q., Rahman, M.N., Koschinsky, M.L., Jia, Z.
Deposit date:2001-03-07
Release date:2001-06-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:High-resolution crystal structure of apolipoprotein(a) kringle IV type 7: insights into ligand binding.
Protein Sci., 10, 2001
1JFN
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1jfn
SOLUTION STRUCTURE OF HUMAN APOLIPOPROTEIN(A) KRINGLE IV TYPE 6
Descriptor:APOLIPOPROTEIN A, KIV-T6
Authors:Maderegger, B., Bermel, W., Hrzenjak, A., Kostner, G.M., Sterk, H.
Deposit date:2001-06-21
Release date:2002-06-28
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of human apolipoprotein(a) kringle IV type 6.
Biochemistry, 41, 2002
1KDU
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1kdu
SEQUENTIAL 1H NMR ASSIGNMENTS AND SECONDARY STRUCTURE OF THE KRINGLE DOMAIN FROM UROKINASE
Descriptor:PLASMINOGEN ACTIVATOR (UROKINASE-TYPE, KRINGLE DOMAIN) (U-PA K) (NMR, MINIMIZED AVERAGE STRUCTURE)
Authors:Li, X., Bokman, A.M., Llinas, M., Smith, R.A.G., Dobson, C.M.
Deposit date:1993-07-15
Release date:1993-10-31
Modification date:2012-08-01
Method:SOLUTION NMR
Cite:Solution structure of the kringle domain from urokinase-type plasminogen activator.
J.Mol.Biol., 235, 1994
1KI0
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1ki0
THE X-RAY STRUCTURE OF HUMAN ANGIOSTATIN
Descriptor:ANGIOSTATIN (E.C. 3.4.21.7)
Authors:Abad, M.C., Arni, R.K., Grella, D.K., Castellino, F.J., Tulinsky, A., Geiger, J.H.
Deposit date:2001-12-02
Release date:2002-05-29
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The X-ray crystallographic structure of the angiogenesis inhibitor angiostatin.
J.Mol.Biol., 318, 2002
1KIV
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1kiv
RECOMBINANT KRINGLE IV-10/M66 VARIANT OF HUMAN APOLIPOPROTEIN(A)
Descriptor:APOLIPOPROTEIN A
Authors:Mochalkin, I., Tulinsky, A., Scanu, A.
Deposit date:1998-08-26
Release date:1999-05-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance.
Biochemistry, 38, 1999
1KRN
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1krn
STRUCTURE OF KRINGLE 4 AT 4C TEMPERATURE AND 1.67 ANGSTROMS RESOLUTION
Descriptor:PLASMINOGEN
Authors:Stec, B., Teeter, M.M., Whitlow, M., Yamano, A.
Deposit date:1995-06-21
Release date:1997-01-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structure of human plasminogen kringle 4 at 1.68 a and 277 K. A possible structural role of disordered residues.
Acta Crystallogr.,Sect.D, 53, 1997
1PK2
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1pk2
SOLUTION STRUCTURE OF THE TISSUE-TYPE PLASMINOGEN ACTIVATOR KRINGLE 2 DOMAIN COMPLEXED TO 6-AMINOHEXANOIC ACID AN ANTIFIBRINOLYTIC DRUG
Descriptor:TISSUE-TYPE PLASMINOGEN ACTIVATOR (T-PA) (KRINGLE 2 DOMAIN) (E.C.3.4.21.68) (NMR, BEST STRUCTURE)
Authors:Llinas, M., Byeon, I.-J.L.
Deposit date:1991-09-16
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the tissue-type plasminogen activator kringle 2 domain complexed to 6-aminohexanoic acid an antifibrinolytic drug.
J.Mol.Biol., 222, 1991
1PK4
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1pk4
CRYSTAL AND MOLECULAR STRUCTURE OF HUMAN PLASMINOGEN KRINGLE 4 REFINED AT 1.9-ANGSTROMS RESOLUTION
Descriptor:PLASMINOGEN KRINGLE 4
Authors:Tulinsky, A., Mulichak, A.M.
Deposit date:1991-07-18
Release date:1993-10-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal and molecular structure of human plasminogen kringle 4 refined at 1.9-A resolution.
Biochemistry, 30, 1991
1PKR
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1pkr
THE STRUCTURE OF RECOMBINANT PLASMINOGEN KRINGLE 1 AND THE FIBRIN BINDING SITE
Descriptor:PLASMINOGEN (KRINGLE 1 DOMAIN)
Authors:Wu, T.-P., Tulinsky, A.
Deposit date:1993-08-03
Release date:1994-01-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:The structure of recombinant plasminogen kringle 1 and the fibrin binding site.
Blood Coagulation Fibrinolysis, 5, 1994
1PMK
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1pmk
KRINGLE-KRINGLE INTERACTIONS IN MULTIMER KRINGLE STRUCTURES
Descriptor:PLASMINOGEN KRINGLE 4 (E.C.3.4.21.7)
Authors:Padmanabhan, K., Tulinsky, A.
Deposit date:1994-04-25
Release date:1994-06-22
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Kringle-kringle interactions in multimer kringle structures.
Protein Sci., 3, 1994
1PML
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1pml
KRINGLE-KRINGLE INTERACTIONS IN MULTIMER KRINGLE STRUCTURES
Descriptor:TISSUE PLASMINOGEN ACTIVATOR KRINGLE 2 (E.C.3.4.21.68)
Authors:Padmanabhan, K., Tulinsky, A.
Deposit date:1994-04-25
Release date:1994-06-22
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Kringle-kringle interactions in multimer kringle structures.
Protein Sci., 3, 1994
1TPK
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1tpk
CRYSTAL STRUCTURE OF THE KRINGLE-2 DOMAIN OF TISSUE PLASMINOGEN ACTIVATOR AT 2.4-ANGSTROMS RESOLUTION
Descriptor:TISSUE PLASMINOGEN ACTIVATOR (KRINGLE 2 DOMAIN) (E.C.3.4.21.31)
Authors:De vos, A.M., Ultsch, M.H., Kelley, R.F., Padmanabhan, K., Tulinsky, A., Westbrook, M.L., Kossiakoff, A.A.
Deposit date:1991-09-24
Release date:1992-07-15
Modification date:2011-07-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-A resolution.
Biochemistry, 31, 1992
1URK
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1urk
SOLUTION STRUCTURE OF THE AMINO TERMINAL FRAGMENT OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR
Descriptor:PLASMINOGEN ACTIVATOR (UROKINASE-TYPE) (AMINO TERMINAL FRAGMENT) (NMR, 15 STRUCTURES)
Authors:Hansen, A.P., Petros, A.M., Meadows, R.P., Nettesheim, D.G., Mazar, A.P., Olejniczak, E.T., Xu, R.X., Pederson, T.M., Henkin, J., Fesik, S.W.
Deposit date:1994-01-10
Release date:1995-05-08
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the amino-terminal fragment of urokinase-type plasminogen activator.
Biochemistry, 33, 1994
2FEB
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2feb
NMR SOLUTION STRUCTURE, DYNAMICS AND BINDING PROPERTIES OF THE KRINGLE IV TYPE 8 MODULE OF APOLIPOPROTEIN(A)
Descriptor:Apolipoprotein(a) (E.C.3.4.21.-)
Authors:Chitayat, S., Kanelis, V., Koschinsky, M.L., Smith, S.P.
Deposit date:2005-12-15
Release date:2006-12-26
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance (NMR) solution structure, dynamics, and binding properties of the kringle IV type 8 module of apolipoprotein(a).
Biochemistry, 46, 2007
2I9A
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2i9a
CRYSTAL STRUCTURE OF THE FREE AMINOTERMINAL FRAGMENT OF UROKINASE TYPE PLASMINOGEN ACTIVATOR (ATF)
Descriptor:Urokinase-type plasminogen activator (E.C.3.4.21.73)
Authors:Lubkowski, J., Barinka, C.
Deposit date:2006-09-05
Release date:2006-11-28
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of interaction between urokinase-type plasminogen activator and its receptor.
J.Mol.Biol., 363, 2006
2K4R
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2k4r
NMR SOLUTION STRUCTURE OF THE NEUROTRYPSIN KRINGLE DOMAIN
Descriptor:Neurotrypsin (E.C.3.4.21.-)
Authors:Ozhogina, O.A.
Deposit date:2008-06-16
Release date:2008-12-09
Method:SOLUTION NMR
Cite:NMR Solution Structure of the Neurotrypsin Kringle Domain
Biochemistry, 47, 2008
2K51
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2k51
NMR SOLUTION STRUCTURE OF THE NEUROTRYPSIN KRINGLE DOMAIN
Descriptor:Neurotrypsin (E.C.3.4.21.-)
Authors:Ozhogina, O.A.
Deposit date:2008-06-23
Release date:2008-12-09
Method:SOLUTION NMR
Cite:NMR Solution Structure of the Neurotrypsin Kringle Domain
Biochemistry, 47, 2008
2KNF
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2knf
SOLUTION STRUCTURE AND FUNCTIONAL CHARACTERIZATION OF HUMAN PLASMINOGEN KRINGLE 5
Descriptor:Plasminogen
Authors:Battistel, M.D., Grishaev, A., An, S.A., Castellino, F.J., Llinas, M.
Deposit date:2009-08-21
Release date:2009-10-27
Modification date:2009-11-10
Method:SOLUTION NMR
Cite:Solution structure and functional characterization of human plasminogen kringle 5.
Biochemistry, 48, 2009
2L0S
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2l0s
SOLUTION STRUCTURE OF HUMAN PLASMINOGEN KRINGLE 3
Descriptor:Plasminogen (E.C.3.4.21.7)
Authors:Christen, M.T., Frank, P., Schaller, J., Llinas, M.
Deposit date:2010-07-15
Release date:2010-08-04
Modification date:2010-09-08
Method:SOLUTION NMR
Cite:Human plasminogen kringle 3: solution structure, functional insights, phylogenetic landscape.
Biochemistry, 49, 2010
2PK4
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2pk4
THE REFINED STRUCTURE OF THE EPSILON-AMINOCAPROIC ACID COMPLEX OF HUMAN PLASMINOGEN KRINGLE
Descriptor:HUMAN PLASMINOGEN KRINGLE 4 COMPLEX WITH EPSILON-AMINOCAPROIC ACID
Authors:Tulinsky, A., Wu, T.-P.
Deposit date:1991-07-18
Release date:1993-10-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The refined structure of the epsilon-aminocaproic acid complex of human plasminogen kringle 4.
Biochemistry, 30, 1991
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