PDB: 25 resultsInfo pagesStatus searchChemie searchBIRD

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6C2F	MBD2 in complex with methylated DNA Descriptor: 12-mer DNA, Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION Authors: Liu, K, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC) Deposit date: 2018-01-08 Release date: 2018-02-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.65 Å) Cite: MBD2 in complex with methylated DNA to be published
2L2L	Solution structure of the coiled-coil complex between MBD2 and p66alpha Descriptor: Methyl-CpG-binding domain protein 2, Transcriptional repressor p66-alpha Authors: Williams Jr, D.C, Scarsdale Jr, N. Deposit date: 2010-08-20 Release date: 2011-05-04 Last modified: 2020-02-05 Method: SOLUTION NMR Cite: p66Alpha-MBD2 coiled-coil interaction and recruitment of Mi-2 are critical for globin gene silencing by the MBD2-NuRD complex. Proc.Natl.Acad.Sci.USA, 108, 2011
7RAY	Crystal structure of MBD2 with DNA Descriptor: DNA (5'-D(*GP*CP*CP*AP*A)-R(P*(5MC))-D(P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION Authors: Liu, K, Dong, A, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2021-07-05 Release date: 2021-07-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Crystal structure of MBD2 with DNA To Be Published
7MWK	Crystal structure of MBD2 with DNA Descriptor: DNA (5'-D(*GP*CP*CP*AP*AP*(MC)P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION Authors: Liu, K, Dong, A, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2021-05-17 Release date: 2021-07-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.453 Å) Cite: Crystal structure of MBD2 with DNA To Be Published
7MWM	Crystal structure of MBD2 with DNA Descriptor: DNA (5'-D(*GP*CP*CP*AP*A)-R(P*(5MC))-D(P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION Authors: Liu, K, Dong, A, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2021-05-17 Release date: 2021-07-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.601 Å) Cite: Crystal structure of MBD2 with DNA To Be Published
2KY8	Solution structure and dynamic analysis of chicken MBD2 methyl binding domain bound to a target methylated DNA sequence Descriptor: DNA (5'-D(*GP*AP*GP*CP*(5CM)P*GP*AP*TP*(TED)P*CP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*TP*(5CM)P*GP*GP*CP*(TED)P*C)-3'), MANGANESE (II) ION, ... Authors: Williams Jr, D.C, Scarsdale Jr, J.N. Deposit date: 2010-05-18 Release date: 2011-05-18 Last modified: 2020-02-05 Method: SOLUTION NMR Cite: Solution structure and dynamic analysis of chicken MBD2 methyl binding domain bound to a target-methylated DNA sequence. Nucleic Acids Res., 39, 2011
7AOA	Structure of the extended MTA1/HDAC1/MBD2/RBBP4 NURD deacetylase complex Descriptor: Histone deacetylase 1, Histone-binding protein RBBP4, INOSITOL HEXAKISPHOSPHATE, ... Authors: Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R. Deposit date: 2020-10-14 Release date: 2020-11-11 Last modified: 2020-12-30 Method: ELECTRON MICROSCOPY (19.4 Å) Cite: The topology of chromatin-binding domains in the NuRD deacetylase complex. Nucleic Acids Res., 48, 2020
7AO9	Structure of the core MTA1/HDAC1/MBD2 NURD deacetylase complex Descriptor: Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, Metastasis-associated protein MTA1, ... Authors: Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R. Deposit date: 2020-10-14 Release date: 2020-11-11 Last modified: 2020-12-30 Method: ELECTRON MICROSCOPY (6.1 Å) Cite: The topology of chromatin-binding domains in the NuRD deacetylase complex. Nucleic Acids Res., 48, 2020
7AO8	Structure of the MTA1/HDAC1/MBD2 NURD deacetylase complex Descriptor: Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, Metastasis-associated protein MTA1, ... Authors: Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R. Deposit date: 2020-10-14 Release date: 2020-11-11 Last modified: 2020-12-30 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: The topology of chromatin-binding domains in the NuRD deacetylase complex. Nucleic Acids Res., 48, 2020
6C1T	MBD2 in complex with a partially methylated DNA Descriptor: 12-mer DNA, GLYCEROL, Methyl-CpG-binding domain protein 2, ... Authors: Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2018-01-05 Release date: 2018-02-14 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. J. Biol. Chem., 293, 2018
6C1U	MBD2 in complex with a deoxy-oligonucleotide Descriptor: 12-mer DNA, Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION Authors: Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2018-01-05 Release date: 2018-02-14 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. J. Biol. Chem., 293, 2018
6C1V	MBD2 in complex with double-stranded DNA Descriptor: 12-mer DNA, Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION Authors: Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2018-01-05 Release date: 2018-02-14 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. J. Biol. Chem., 293, 2018
6C1A	MBD2 in complex with methylated DNA Descriptor: Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION, complement to dna strand 1, ... Authors: Liu, K, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2018-01-04 Release date: 2018-02-14 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. J. Biol. Chem., 293, 2018
6CNQ	MBD2 in complex with methylated DNA Descriptor: DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION Authors: Liu, K, Xu, C, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2018-03-08 Release date: 2018-03-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.151 Å) Cite: Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. J. Biol. Chem., 293, 2018
6CNP	Crystal structure of MBD2 complex with methylated CpG island Descriptor: CALCIUM ION, DNA (5'-D(*GP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain protein 2, ... Authors: Xu, C, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2018-03-08 Release date: 2018-03-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. J. Biol. Chem., 293, 2018
6CEV	MBD3 MBD in complex with methylated, non-palindromic CpG DNA: alternative interpretation of crystallographic data Descriptor: DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*CP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*GP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain protein 3, ... Authors: Liu, K, Tempel, W, Wernimont, A.K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2018-02-12 Release date: 2018-05-09 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.005 Å) Cite: Structural analyses reveal that MBD3 is a methylated CG binder. Febs J., 286, 2019
6CEU	MBD3 MBD in complex with methylated, non-palindromic CpG DNA: alternative interpretation of crystallographic data Descriptor: DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*CP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*GP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain protein 3, ... Authors: Liu, K, Tempel, W, Wernimont, A.K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2018-02-12 Release date: 2018-05-09 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.005 Å) Cite: Structural analyses reveal that MBD3 is a methylated CG binder. Febs J., 286, 2019
6CC8	Crystal structure MBD3 MBD domain in complex with methylated CpG DNA Descriptor: Methyl-CpG-binding domain protein 3, UNKNOWN ATOM OR ION, methylated CpG DNA Authors: Liu, K, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2018-02-06 Release date: 2018-04-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural analyses reveal that MBD3 is a methylated CG binder. Febs J., 286, 2019
6CCG	Crystal structure MBD3 MBD domain in complex with methylated CpG DNA Descriptor: DNA, Methyl-CpG-binding domain protein 3, UNKNOWN ATOM OR ION Authors: Liu, K, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2018-02-07 Release date: 2018-05-09 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural analyses reveal that MBD3 is a methylated CG binder. Febs J., 286, 2019
2MB7	Solution structure of MBD3 methylcytosine binding domain Descriptor: Methyl-CpG-binding domain protein 3 Authors: Williams Jr, D.C, Scarsdale, J.N. Deposit date: 2013-07-26 Release date: 2013-12-11 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Probing the Dynamic Distribution of Bound States for Methylcytosine-binding Domains on DNA. J.Biol.Chem., 289, 2014
6OGJ	MeCP2 MBD in complex with DNA Descriptor: DNA (5'-D(*CP*GP*GP*AP*GP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*CP*AP*CP*TP*CP*CP*G)-3'), Methyl-CpG-binding protein 2, ... Authors: Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2019-04-02 Release date: 2019-05-01 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain. Biochim Biophys Acta Gene Regul Mech, 1862, 2019
6OGK	MeCP2 MBD in complex with DNA Descriptor: CALCIUM ION, DNA (5'-D(*CP*GP*GP*AP*GP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*CP*TP*CP*CP*G)-3'), ... Authors: Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC) Deposit date: 2019-04-02 Release date: 2019-05-01 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain. Biochim Biophys Acta Gene Regul Mech, 1862, 2019
2LQB	Metal binding repeat 2 of the Wilson disease protein (ATP7B) Descriptor: Copper-transporting ATPase 2 Authors: Nokhrin, S, Dolgova, N.V, Yu, C, Dmitriev, O.Y. Deposit date: 2012-02-28 Release date: 2013-07-03 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification. Biochem.J., 454, 2013
6C1Y	mbd of human mecp2 in complex with methylated DNA Descriptor: 12-mer DNA, Methyl-CpG-binding protein 2, UNKNOWN ATOM OR ION Authors: Liu, K, Bian, C, Tempel, W, Wernimont, A.K, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2018-01-05 Release date: 2018-02-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain. Biochim Biophys Acta Gene Regul Mech, 1862, 2019
7LU8	Structure of the cryptic HMA domain of the human copper transporter ATP7A Descriptor: Copper-transporting ATPase 1 Authors: Lee, W, Uhlemann, E.E, Tonelli, M, Dmitriev, O.Y. Deposit date: 2021-02-21 Release date: 2021-09-15 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: At sixes and sevens: cryptic domain in the metal binding chain of the human copper transporter ATP7A. Biophys.J., 120, 2021