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2H7H	Crystal structure of the JUN BZIP homodimer complexed with AP-1 DNA Descriptor: 5'-D(*CP*GP*TP*CP*GP*AP*TP*GP*AP*CP*TP*CP*AP*TP*CP*GP*AP*CP*G)-3', 5'-D(*CP*GP*TP*CP*GP*AP*TP*GP*AP*GP*TP*CP*AP*TP*CP*GP*AP*CP*G)-3', Viral jun transforming protein Authors: Rajan, S.S, Borovilos, M, Cuff, M.E, Kim, Y. Deposit date: 2006-06-02 Release date: 2007-06-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of the JUN BZIP homodimer complexed with AP-1 DNA To be Published
1FOS	TWO HUMAN C-FOS:C-JUN:DNA COMPLEXES Descriptor: C-JUN PROTO-ONCOGENE PROTEIN, DNA (5'-D(*AP*AP*TP*GP*GP*AP*TP*GP*AP*GP*TP*CP*AP*TP*AP*GP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*AP*TP*CP*CP*AP*T)-3'), ... Authors: Glover, J.N.M, Harrison, S.C. Deposit date: 1995-03-07 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.05 Å) Cite: Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA. Nature, 373, 1995
1PXZ	1.7 Angstrom Crystal Structure of jun a 1, the major allergen from cedar pollen Descriptor: Major pollen allergen Jun a 1 Authors: Czerwinski, E.W, White, M.A, Midoro-Horiuti, T, Brooks, E.G, Goldblum, R.M. Deposit date: 2003-07-07 Release date: 2004-11-16 Last modified: 2017-10-11 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of Jun a 1, the major cedar pollen allergen from Juniperus ashei, reveals a parallel beta-helical core. J.Biol.Chem., 280, 2005
1A02	STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA Descriptor: AP-1 FRAGMENT FOS, AP-1 FRAGMENT JUN, DNA (5'-D(*DAP*DAP*DCP*DTP*DAP*DTP*DGP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DTP*DTP*DTP*DTP*DCP*DC)-3'), ... Authors: Chen, L, Glover, J.N.M, Hogan, P.G, Rao, A, Harrison, S.C. Deposit date: 1997-12-08 Release date: 1998-05-27 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA. Nature, 392, 1998
1T2K	Structure Of The DNA Binding Domains Of IRF3, ATF-2 and Jun Bound To DNA Descriptor: 31-MER, Cyclic-AMP-dependent transcription factor ATF-2, Interferon regulatory factor 3, ... Authors: Panne, D, Maniatis, T, Harrison, S.C. Deposit date: 2004-04-21 Release date: 2004-11-16 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer. Embo J., 23, 2004
1JUN	NMR STUDY OF C-JUN HOMODIMER Descriptor: C-JUN HOMODIMER Authors: Junius, F.K, O'Donoghue, S.I, Nilges, M, King, G.F. Deposit date: 1995-12-19 Release date: 1996-06-20 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: High resolution NMR solution structure of the leucine zipper domain of the c-Jun homodimer. J.Biol.Chem., 271, 1996
2H96	Discovery of Potent, Highly Selective, and Orally Bioavailable Pyridine Carboxamide C-jun NH2-terminal Kinase Inhibitors Descriptor: 5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE, C-jun-amino-terminal kinase-interacting protein 1, GLYCEROL, ... Authors: Abad-Zapatero, C. Deposit date: 2006-06-09 Release date: 2006-07-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3 Å) Cite: Discovery of potent, highly selective, and orally bioavailable pyridine carboxamide c-Jun NH2-terminal kinase inhibitors. J.Med.Chem., 49, 2006
6NOA	Solution Structure of the RNA element that recruits eIF3 to the 5'-UTR of c-Jun and regulates specialized translation initiation (apical loop) Descriptor: C-JUN SL1 Authors: Walker, M, Shortridge, M, Varani, G. Deposit date: 2019-01-16 Release date: 2020-07-22 Last modified: 2020-11-18 Method: SOLUTION NMR Cite: Structure of the RNA Specialized Translation Initiation Element that Recruits eIF3 to the 5'-UTR of c-Jun. J.Mol.Biol., 432, 2020
2GMX	Selective Aminopyridine-Based C-Jun N-terminal Kinase inhibitors with cellular activity Descriptor: C-jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 8, N-(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2-YL)-2-(4-BROMO-2,5-DIMETHOXYPHENYL)ACETAMIDE, ... Authors: Abad-Zapatero, C. Deposit date: 2006-04-07 Release date: 2006-06-06 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Aminopyridine-Based c-Jun N-Terminal Kinase Inhibitors with Cellular Activity and Minimal Cross-Kinase Activity. J.Med.Chem., 49, 2006
6MXQ	Solution structure of a c-JUN 5' UTR stem-loop associated with specialized cap-dependent translation initiation Descriptor: RNA C-JUN TL Authors: Walker, M, Shortridge, M, Varani, G. Deposit date: 2018-10-31 Release date: 2020-05-06 Last modified: 2020-11-18 Method: SOLUTION NMR Cite: Structure of the RNA Specialized Translation Initiation Element that Recruits eIF3 to the 5'-UTR of c-Jun. J.Mol.Biol., 432, 2020
2P33	Synthesis and SAR of Aminopyrimidines as Novel c-Jun N-Terminal Kinase (JNK) Inhibitors Descriptor: 4-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-N-ethylpiperidine-1-carboxamide, c-Jun N-terminal kinase 3 Authors: Ceska, T.A, Platt, A, Fortunato, M, Dickson, K.M, Sharpe, A. Deposit date: 2007-03-08 Release date: 2007-06-19 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Synthesis and SAR of aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors Bioorg.Med.Chem.Lett., 17, 2007
2D0D	Crystal Structure of a Meta-cleavage Product Hydrolase (CumD) A129V Mutant Descriptor: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase, CHLORIDE ION, PHOSPHATE ION Authors: Jun, S.Y, Fushinobu, S, Nojiri, H, Omori, T, Shoun, H, Wakagi, T. Deposit date: 2005-08-01 Release date: 2006-06-06 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Improving the catalytic efficiency of a meta-cleavage product hydrolase (CumD) from Pseudomonas fluorescens IP01 Biochim.Biophys.Acta, 1764, 2006
4QIW	Crystal structure of euryarchaeal RNA polymerase from Thermococcus kodakarensis Descriptor: DNA-directed RNA polymerase, DNA-directed RNA polymerase subunit A'', DNA-directed RNA polymerase subunit D, ... Authors: Jun, S.-H, Murakami, K.S. Deposit date: 2014-06-02 Release date: 2014-10-08 Last modified: 2014-11-26 Method: X-RAY DIFFRACTION (3.5 Å) Cite: The X-ray crystal structure of the euryarchaeal RNA polymerase in an open-clamp configuration. Nat Commun, 5, 2014
5DQP	EDTA monooxygenase (EmoA) from Chelativorans sp. BNC1 Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, EDTA monooxygenase, SULFATE ION Authors: Jun, S.Y, Youn, B, Xun, L, Kang, C, Lewis, K.M. Deposit date: 2015-09-15 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.146 Å) Cite: Structural and biochemical characterization of EDTA monooxygenase and its physical interaction with a partner flavin reductase. Mol.Microbiol., 100, 2016
6KF9	Cryo-EM structure of Thermococcus kodakarensis RNA polymerase Descriptor: DNA (27-MER), DNA (5'-D(P*TP*CP*GP*GP*TP*AP*AP*TP*CP*AP*CP*GP*CP*TP*CP*C)-3'), DNA-directed RNA polymerase subunit, ... Authors: Jun, S.-H, Hyun, J, Jeong, H, Cha, J.S, Kim, H, Bartlett, M.S, Cho, H.-S, Murakami, K.S. Deposit date: 2019-07-07 Release date: 2020-07-01 Last modified: 2022-03-23 Method: ELECTRON MICROSCOPY (3.79 Å) Cite: Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase. Nat Commun, 11, 2020
6KF3	Cryo-EM structure of Thermococcus kodakarensis RNA polymerase Descriptor: DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit A'', DNA-directed RNA polymerase subunit D, ... Authors: Jun, S.-H, Hyun, J, Jeong, H, Cha, J.S, Kim, H, Bartlett, M.S, Cho, H.-S, Murakami, K.S. Deposit date: 2019-07-06 Release date: 2020-07-01 Last modified: 2022-03-23 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase. Nat Commun, 11, 2020
6KF4	Cryo-EM structure of Thermococcus kodakarensis RNA polymerase Descriptor: DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit A'', DNA-directed RNA polymerase subunit D, ... Authors: Jun, S.-H, Hyun, J, Jeong, H, Cha, J.S, Kim, H, Bartlett, M.S, Cho, H.-S, Murakami, K.S. Deposit date: 2019-07-06 Release date: 2020-07-01 Last modified: 2022-03-23 Method: ELECTRON MICROSCOPY (3.97 Å) Cite: Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase. Nat Commun, 11, 2020
6AT7	Phenylalanine Ammonia-Lyase (PAL) from Sorghum bicolor Descriptor: AMMONIUM ION, Phenylalanine ammonia-lyase Authors: Jun, S.Y, Kang, C. Deposit date: 2017-08-28 Release date: 2018-01-31 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.493 Å) Cite: Biochemical and Structural Analysis of Substrate Specificity of a Phenylalanine Ammonia-Lyase. Plant Physiol., 176, 2018
5LW1	Crystal structure of DARPin-DARPin rigid fusion, variant DD_232_11_D12 in complex JNK1a1 and JIP1 peptide Descriptor: ADENOSINE, C-Jun-amino-terminal kinase-interacting protein 1, DD_232_11_D12, ... Authors: Wu, Y, Batyuk, A, Mittl, P.R, Honegger, A, Plueckthun, A. Deposit date: 2016-09-15 Release date: 2017-12-13 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural Basis for the Selective Inhibition of c-Jun N-Terminal Kinase 1 Determined by Rigid DARPin-DARPin Fusions. J.Mol.Biol., 430, 2018
1S9K	Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site Descriptor: Human IL-2 ARRE1 Promoter Element, Minus Strand, Plus Strand, ... Authors: Wang, D, Stroud, J.C, Chen, L. Deposit date: 2004-02-04 Release date: 2005-06-14 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site To be Published
4Y46	Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) inhibitors Descriptor: 1-{trans-4-[(8-cyclopentyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]cyclohexyl}-3-propan-2-ylurea, Mitogen-activated protein kinase 10 Authors: Park, H. Deposit date: 2015-02-10 Release date: 2015-05-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) Inhibitors. Acs Med.Chem.Lett., 6, 2015
4Y5H	Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) inhibitors Descriptor: 1-(trans-4-{[7-oxo-8-(propan-2-yl)-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}cyclohexyl)-3-propan-2-ylurea, Mitogen-activated protein kinase 10 Authors: Park, H. Deposit date: 2015-02-11 Release date: 2015-05-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.055 Å) Cite: Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) Inhibitors. Acs Med.Chem.Lett., 6, 2015
7P20	High resolution structure of the Juniperus ashei allergen - Jun a 3 Descriptor: CHLORIDE ION, Pathogenesis-related 5 protein Jun a 3.0101 Authors: Eder, M, Hofer, G, Keller, W. Deposit date: 2021-07-03 Release date: 2022-07-13 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal structure of the allergen Jun a 3 the Thaumatin-like protein of Juniperus ashei To Be Published
2G01	Pyrazoloquinolones as Novel, Selective JNK1 inhibitors Descriptor: 6-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONE, C-jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 8, ... Authors: Abad-Zapatero, C. Deposit date: 2006-02-10 Release date: 2006-04-18 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Synthesis and SAR of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones as novel, selective c-Jun N-terminal kinase inhibitors. Bioorg.Med.Chem.Lett., 16, 2006
1JNM	Crystal Structure of the Jun/CRE Complex Descriptor: 5'-D(*CP*GP*TP*CP*GP*AP*TP*GP*AP*CP*GP*TP*CP*AP*TP*CP*GP*AP*CP*G)-3', PROTO-ONCOGENE C-JUN Authors: Kim, Y, Podust, L.M. Deposit date: 2001-07-24 Release date: 2003-06-03 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure of the Jun bZIP homodimer complexed with CRE To be Published

 

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