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2LY4
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BU of 2ly4 by Molmil
HMGB1-facilitated p53 DNA binding occurs via HMG-box/p53 transactivation domain interaction and is regulated by the acidic tail
Descriptor: Cellular tumor antigen p53, High mobility group protein B1
Authors:Rowell, J.P, Simpson, K.L, Stott, K, Watson, M, Thomas, J.O.
Deposit date:2012-09-12
Release date:2012-10-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:HMGB1-Facilitated p53 DNA Binding Occurs via HMG-Box/p53 Transactivation Domain Interaction, Regulated by the Acidic Tail.
Structure, 20, 2012
2RTU
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BU of 2rtu by Molmil
Solution structure of oxidized human HMGB1 A box
Descriptor: High mobility group protein B1
Authors:Jing, W, Tochio, N, Tate, S.
Deposit date:2013-09-12
Release date:2014-03-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Redox-sensitive structural change in the A-domain of HMGB1 and its implication for the binding to cisplatin modified DNA.
Biochem.Biophys.Res.Commun., 441, 2013
8I9M
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BU of 8i9m by Molmil
The RAGE and HMGB1 complex
Descriptor: Advanced glycosylation end product-specific receptor, High mobility group protein B1
Authors:Han, C.W, Kim, H.J.
Deposit date:2023-02-07
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (5.19 Å)
Cite:The RAGE and HMGB1 complex
To Be Published
4QR9
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BU of 4qr9 by Molmil
Crystal structure of two HMGB1 Box A domains cooperating to underwind and kink a DNA
Descriptor: DNA (5'-D(*AP*TP*AP*TP*CP*GP*AP*TP*AP*T)-3'), High mobility group protein B1, MAGNESIUM ION
Authors:Sanchez-Giraldo, R, Acosta-Reyes, F.J, Malarkey, C.S, Saperas, N, Churchill, M.E.A, Campos, J.L.
Deposit date:2014-06-30
Release date:2015-07-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Two high-mobility group box domains act together to underwind and kink DNA.
Acta Crystallogr.,Sect.D, 71, 2015
2MSY
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BU of 2msy by Molmil
Solution structure of Hox homeodomain
Descriptor: Homeobox protein Hox-C9
Authors:Kim, H, Park, S, Han, J, Lee, B.
Deposit date:2014-08-11
Release date:2015-09-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural insight into the interaction between the Hox and HMGB1 and understanding of the HMGB1-enhancing effect of Hox-DNA binding.
Biochim.Biophys.Acta, 1854, 2015
2RRR
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BU of 2rrr by Molmil
DNA oligomer containing ethylene cross-linked cyclic 2'-deoxyuridylate dimer
Descriptor: DNA (5'-D(*CP*CP*TP*TP*CP*AP*TP*TP*AP*CP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*GP*TP*AP*AP*TP*GP*AP*AP*GP*G)-3')
Authors:Furuita, K, Murata, S, Jee, J.G, Ichikawa, S, Matsuda, A, Kojima, C.
Deposit date:2011-03-24
Release date:2011-06-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Feature of Bent DNA Recognized by HMGB1
J.Am.Chem.Soc., 133, 2011
2RRQ
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BU of 2rrq by Molmil
DNA oligomer containing propylene cross-linked cyclic 2'-deoxyuridylate dimer
Descriptor: DNA (5'-D(*CP*CP*TP*TP*CP*AP*(JDT)P*TP*AP*CP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*GP*TP*AP*AP*TP*GP*AP*AP*GP*G)-3')
Authors:Furuita, K, Murata, S, Jee, J.G, Ichikawa, S, Matsuda, A, Kojima, C.
Deposit date:2011-03-24
Release date:2011-06-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Feature of Bent DNA Recognized by HMGB1
J.Am.Chem.Soc., 133, 2011
6CIJ
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BU of 6cij by Molmil
Cryo-EM structure of mouse RAG1/2 HFC complex containing partial HMGB1 linker(3.9 A)
Descriptor: CALCIUM ION, DNA (30-MER), DNA (41-MER), ...
Authors:Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W.
Deposit date:2018-02-24
Release date:2018-04-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
5ZE2
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BU of 5ze2 by Molmil
Hairpin Complex, RAG1/2-hairpin 12RSS/23RSS complex in 5mM Mn2+ for 2 min at 4'C
Descriptor: 1,2-ETHANEDIOL, DNA (30-MER), DNA (31-MER), ...
Authors:Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W.
Deposit date:2018-02-25
Release date:2018-04-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
5ZE0
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BU of 5ze0 by Molmil
Hairpin Forming Complex, RAG1/2-Nicked(with Dideoxy) 12RSS/23RSS complex in Mg2+
Descriptor: 1,2-ETHANEDIOL, DNA (30-MER), DNA (39-MER), ...
Authors:Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W.
Deposit date:2018-02-25
Release date:2018-04-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
5ZE1
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BU of 5ze1 by Molmil
Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in 2mM Mn2+ for 10 min at 4'C
Descriptor: 1,2-ETHANEDIOL, DNA, HMGB1 A-B box, ...
Authors:Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W.
Deposit date:2018-02-25
Release date:2018-04-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
5ZDZ
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BU of 5zdz by Molmil
Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in Ca2+
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DNA (30-MER), ...
Authors:Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W.
Deposit date:2018-02-25
Release date:2018-04-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
2GZK
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BU of 2gzk by Molmil
Structure of a complex of tandem HMG boxes and DNA
Descriptor: 5'-D(*GP*CP*AP*TP*TP*GP*TP*TP*TP*AP*GP*AP*TP*CP*CP*C)-3', 5'-D(*GP*GP*GP*AP*TP*CP*TP*AP*AP*AP*CP*AP*AP*TP*GP*C)-3', Sex-determining region on Y / HMGB1
Authors:Stott, K, Tang, G.S, Lee, K.B, Thomas, J.O.
Deposit date:2006-05-11
Release date:2006-07-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of a Complex of Tandem HMG Boxes and DNA.
J.Mol.Biol., 360, 2006
2YRQ
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BU of 2yrq by Molmil
Solution structure of the tandem HMG box domain from Human High mobility group protein B1
Descriptor: High mobility group protein B1
Authors:Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-02
Release date:2008-02-12
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the tandem HMG box domain from Human High mobility group protein B1
To be Published
6CIK
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BU of 6cik by Molmil
Pre-Reaction Complex, RAG1(E962Q)/2-intact/nicked 12/23RSS complex in Mn2+
Descriptor: DNA (5'-D(*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3'), High mobility group protein B1, Intact 12RSS substrate forward strand, ...
Authors:Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W.
Deposit date:2018-02-24
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
6CIL
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BU of 6cil by Molmil
PRE-REACTION COMPLEX, RAG1(E962Q)/2-INTACT/INTACT 12/23RSS COMPLEX IN MN2+
Descriptor: High mobility group protein B1, Intact 12RSS substrate forward strand, Intact 12RSS substrate reverse strand, ...
Authors:Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W.
Deposit date:2018-02-24
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.15 Å)
Cite:Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
6CIM
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BU of 6cim by Molmil
Pre-Reaction Complex, RAG1(E962Q)/2-nicked/intact 12/23RSS complex in Mn2+
Descriptor: DNA (5'-D(*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3'), High mobility group protein B1, Intact 23RSS substrate forward strand, ...
Authors:Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W.
Deposit date:2018-02-24
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
6CG0
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BU of 6cg0 by Molmil
Cryo-EM structure of mouse RAG1/2 HFC complex (3.17 A)
Descriptor: CALCIUM ION, DNA (30-MER), DNA (41-MER), ...
Authors:Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W.
Deposit date:2018-02-19
Release date:2018-04-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
6OEO
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BU of 6oeo by Molmil
Cryo-EM structure of mouse RAG1/2 NFC complex (DNA1)
Descriptor: CALCIUM ION, DNA (46-MER), DNA (57-MER), ...
Authors:Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
Deposit date:2019-03-27
Release date:2020-01-29
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
6OEM
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BU of 6oem by Molmil
Cryo-EM structure of mouse RAG1/2 PRC complex (DNA0)
Descriptor: DNA (46-MER), DNA (57-MER), High mobility group protein B1, ...
Authors:Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
Deposit date:2019-03-27
Release date:2020-01-29
Last modified:2020-02-26
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
6OEN
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BU of 6oen by Molmil
Cryo-EM structure of mouse RAG1/2 PRC complex (DNA1)
Descriptor: CALCIUM ION, DNA (46-MER), DNA (57-MER), ...
Authors:Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
Deposit date:2019-03-27
Release date:2020-01-29
Last modified:2020-02-26
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
6OER
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BU of 6oer by Molmil
Cryo-EM structure of mouse RAG1/2 NFC complex (DNA2)
Descriptor: CALCIUM ION, DNA (46-MER), DNA (57-MER), ...
Authors:Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
Deposit date:2019-03-27
Release date:2020-01-29
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
3JBY
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BU of 3jby by Molmil
Cryo-electron microscopy structure of RAG Paired Complex (C2 symmetry)
Descriptor: '-D(P*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3', 5'-D(P*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', CALCIUM ION, ...
Authors:Ru, H, Chambers, M.G, Fu, T.-M, Tong, A.B, Liao, M, Wu, H.
Deposit date:2015-10-22
Release date:2015-12-09
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
3JBX
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BU of 3jbx by Molmil
Cryo-electron microscopy structure of RAG Signal End Complex (C2 symmetry)
Descriptor: 5'-D(*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', 5'-D(*GP*CP*GP*AP*TP*GP*GP*TP*TP*AP*AP*CP*CP*A)-3', 5'-D(P*GP*TP*CP*TP*GP*TP*AP*GP*CP*AP*CP*TP*GP*TP*G)-3', ...
Authors:Ru, H, Chambers, M.G, Fu, T.-M, Tong, A.B, Liao, M, Wu, H.
Deposit date:2015-10-22
Release date:2015-12-09
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
3JBW
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BU of 3jbw by Molmil
Cryo-electron microscopy structure of RAG Paired Complex (with NBD, no symmetry)
Descriptor: 12-RSS signal end forward strand, 5'-D(P*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3', Nicked 12-RSS intermediate reverse strand, ...
Authors:Ru, H, Chambers, M.G, Fu, T.-M, Tong, A.B, Liao, M, Wu, H.
Deposit date:2015-10-21
Release date:2015-12-09
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015

 

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