PDB: 42 resultsInfo pagesStatus searchChemie searchBIRD

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3IVF	Crystal structure of the talin head FERM domain Descriptor: Talin-1 Authors: Elliott, P.R, Goult, B.T, Bate, N, Grossmann, J.G, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L. Deposit date: 2009-09-01 Release date: 2010-08-18 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.94 Å) Cite: The Structure of the talin head reveals a novel extended conformation of the FERM domain Structure, 18, 2010
6U4K	Human talin2 residues 1-403 Descriptor: Talin-2 Authors: Izard, T, Rangarajan, E.S, Colgan, L, Yasuda, R, Chinthalapudi, K. Deposit date: 2019-08-26 Release date: 2020-07-08 Last modified: 2020-09-23 Method: X-RAY DIFFRACTION (2.555 Å) Cite: A distinct talin2 structure directs isoform specificity in cell adhesion. J.Biol.Chem., 295, 2020
5EJR	Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain Descriptor: 1,2-ETHANEDIOL, Myosin-I heavy chain Authors: Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Clause, J, Titus, M.A, Houdusse, A. Deposit date: 2015-11-02 Release date: 2016-07-06 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Myosin MyTH4-FERM structures highlight important principles of convergent evolution. Proc.Natl.Acad.Sci.USA, 113, 2016
3G9W	Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Integrin beta-1D, ... Authors: Anthis, N.J, Wegener, K.L, Ye, F, Kim, C, Lowe, E.D, Vakonakis, I, Bate, N, Critchley, D.R, Ginsberg, M.H, Campbell, I.D. Deposit date: 2009-02-15 Release date: 2009-10-20 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.165 Å) Cite: The structure of an integrin/talin complex reveals the basis of inside-out signal transduction Embo J., 28, 2009
8FSE	Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain Descriptor: Integrin beta-2,Talin-1 Authors: Wu, J, Gao, T. Deposit date: 2023-01-09 Release date: 2024-07-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation Biorxiv, 2024
8FTB	Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with a K306Q mutation Descriptor: Integrin beta-2,Talin-1 Authors: Wu, J, Gao, T. Deposit date: 2023-01-11 Release date: 2024-07-03 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation Biorxiv, 2024
5EJS	Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain, mutant 1 Descriptor: Myosin-I heavy chain Authors: Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Titus, M.A, Houdusse, A. Deposit date: 2015-11-02 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Myosin MyTH4-FERM structures highlight important principles of convergent evolution. Proc.Natl.Acad.Sci.USA, 113, 2016
6VGU	Crystal structure of FERM-folded talin head domain bound to the NPLY motif of beta3-integrin Descriptor: Integrin beta-3,Talin-1 Authors: Zhang, P, Sun, Y, Wu, J. Deposit date: 2020-01-09 Release date: 2020-12-16 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding. Proc.Natl.Acad.Sci.USA, 117, 2020
1Y19	Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions Descriptor: Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1 Authors: de Pereda, J.M, Wegener, K, Santelli, E, Bate, N, Ginsberg, M.H, Critchley, D.R, Campbell, I.D, Liddington, R.C. Deposit date: 2004-11-17 Release date: 2005-01-04 Last modified: 2016-11-30 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions J.Biol.Chem., 280, 2005
5MV7	Structure of human Myosin 7b C-terminal MyTH4-FERM MF2 domain Descriptor: SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Unconventional myosin-VIIb Authors: Planelles-Herrero, V.J, Sourigues, Y, Titus, M.A, Houdusse, A. Deposit date: 2017-01-15 Release date: 2017-07-05 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
5MV9	Structure of human Myosin 7a C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain Descriptor: ACETATE ION, Unconventional myosin-VIIa, cDNA FLJ51329, ... Authors: Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. Deposit date: 2017-01-16 Release date: 2017-07-05 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
5MV8	Structure of human Myosin 7b C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain Descriptor: GLYCEROL, MAGNESIUM ION, Unconventional myosin-VIIb, ... Authors: Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. Deposit date: 2017-01-16 Release date: 2017-07-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
1MK7	CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA Descriptor: Integrin Beta3, TALIN Authors: Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. Deposit date: 2002-08-28 Release date: 2003-01-28 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Determinants of Integrin Recognition by Talin Mol.Cell, 11, 2003
1MIX	Crystal structure of a FERM domain of Talin Descriptor: Talin Authors: Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. Deposit date: 2002-08-23 Release date: 2003-01-28 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural determinants of integrin recognition by talin Mol.Cell, 11, 2003
1MIZ	Crystal structure of an integrin beta3-talin chimera Descriptor: TALIN, integrin beta3 Authors: Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. Deposit date: 2002-08-23 Release date: 2003-01-28 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural determinants of integrin recognition by talin Mol.Cell, 11, 2003
1MK9	CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA Descriptor: Integrin Beta3, TALIN Authors: Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. Deposit date: 2002-08-28 Release date: 2003-01-28 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Determinants of Integrin Recognition by Talin Mol.Cell, 11, 2003
1QQG	CRYSTAL STRUCTURE OF THE PH-PTB TARGETING REGION OF IRS-1 Descriptor: INSULIN RECEPTOR SUBSTRATE 1 Authors: Dhe-Paganon, S, Shoelson, S.E. Deposit date: 1999-06-04 Release date: 1999-08-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1. Proc.Natl.Acad.Sci.USA, 96, 1999

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