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4G7T
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BU of 4g7t by Molmil
Rat Heme Oxygenase-1 in complex with Heme and CO with 1 hr Illumination: Laser on
Descriptor: CARBON MONOXIDE, FORMIC ACID, Heme oxygenase 1, ...
Authors:Sugishima, M, Moffat, K, Noguchi, M.
Deposit date:2012-07-20
Release date:2012-10-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discrimination between CO and O(2) in heme oxygenase: comparison of static structures and dynamic conformation changes following CO photolysis.
Biochemistry, 51, 2012
4G7P
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BU of 4g7p by Molmil
Rat Heme Oxygenase-1 in complex with Heme and CO with 1 hr Illumination at 100 K: Laser off
Descriptor: CARBON MONOXIDE, FORMIC ACID, Heme oxygenase 1, ...
Authors:Sugishima, M, Moffat, K, Noguchi, M.
Deposit date:2012-07-20
Release date:2012-10-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discrimination between CO and O(2) in heme oxygenase: comparison of static structures and dynamic conformation changes following CO photolysis.
Biochemistry, 51, 2012
4G7U
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BU of 4g7u by Molmil
Rat Heme Oxygenase-1 in complex with Heme and CO with 16 hr Illumination: Laser off
Descriptor: CARBON MONOXIDE, FORMIC ACID, Heme oxygenase 1, ...
Authors:Sugishima, M, Moffat, K, Noguchi, M.
Deposit date:2012-07-20
Release date:2012-10-31
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discrimination between CO and O(2) in heme oxygenase: comparison of static structures and dynamic conformation changes following CO photolysis.
Biochemistry, 51, 2012
3TGM
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BU of 3tgm by Molmil
X-Ray Crystal Structure of Human Heme Oxygenase-1 in Complex with 1-(1H-imidazol-1-yl)-4,4-diphenyl-2 butanone
Descriptor: 1-(1H-imidazol-1-yl)-4,4-diphenylbutan-2-one, HEXANE-1,6-DIOL, Heme oxygenase 1, ...
Authors:Rahman, M.N, Jia, Z.
Deposit date:2011-08-17
Release date:2012-02-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A novel, "double-clamp" binding mode for human heme oxygenase-1 inhibition.
Plos One, 7, 2012
3MOO
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BU of 3moo by Molmil
Crystal structure of the HmuO, heme oxygenase from Corynebacterium diphtheriae, in complex with azide-bound verdoheme
Descriptor: 5-OXA-PROTOPORPHYRIN IX CONTAINING FE, AZIDE ION, Heme oxygenase, ...
Authors:Omori, K, Matsui, T, Unno, M, Ikeda-Saito, M.
Deposit date:2010-04-22
Release date:2011-03-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Enzymatic ring-opening mechanism of verdoheme by the heme oxygenase: a combined X-ray crystallography and QM/MM study.
J.Am.Chem.Soc., 132, 2010
3K4F
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BU of 3k4f by Molmil
X-Ray Crystal Structure of Human Heme Oxygenase-1 in Complex with 4-Phenyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone
Descriptor: 4-phenyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one, HEXANE-1,6-DIOL, Heme oxygenase 1, ...
Authors:Rahman, M.N, Jia, Z.
Deposit date:2009-10-05
Release date:2009-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Heme Oxygenase Inhibition by 2-Oxy-substituted 1-Azolyl-4-phenylbutanes: Effect of Variation of the Azole Moiety. X-Ray Crystal Structure of Human Heme Oxygenase-1 in Complex with 4-Phenyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone.
Chem.Biol.Drug Des., 75, 2010
3I9T
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BU of 3i9t by Molmil
Crystal structure of the rat heme oxygenase (HO-1) in complex with heme binding dithiothreitol (DTT)
Descriptor: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Matsui, T, Unno, M, Ikeda-Saito, M.
Deposit date:2009-07-13
Release date:2010-05-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Dioxygen activation for the self-degradation of heme: reaction mechanism and regulation of heme oxygenase.
Inorg.Chem., 49, 2010
3I9U
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BU of 3i9u by Molmil
Crystal structure of the rat heme oxygenase (HO-1) in complex with heme binding dithioerythritol (DTE)
Descriptor: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Matsui, T, Unno, M, Ikeda-Saito, M.
Deposit date:2009-07-13
Release date:2010-05-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Dioxygen activation for the self-degradation of heme: reaction mechanism and regulation of heme oxygenase.
Inorg.Chem., 49, 2010
3I8R
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BU of 3i8r by Molmil
Crystal structure of the heme oxygenase from Corynebacterium diphtheriae (HmuO) in complex with heme binding ditiothreitol (DTT)
Descriptor: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Heme oxygenase, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Matsui, T, Unno, M, Ikeda-Saito, M.
Deposit date:2009-07-10
Release date:2010-05-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Dioxygen activation for the self-degradation of heme: reaction mechanism and regulation of heme oxygenase.
Inorg.Chem., 49, 2010
3HOK
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BU of 3hok by Molmil
X-ray Crystal Structure of Human Heme Oxygenase-1 with (2R, 4S)-2-[2-(4-Chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-4[((5-trifluoromethylpyridin-2-yl)thio)methyl]-1,3-dioxolane: A Novel, Inducible Binding Mode
Descriptor: 2-({[(2R,4S)-2-[2-(4-chlorophenyl)ethyl]-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl}sulfanyl)-5-(trifluoromethyl)pyridine, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Rahman, M.N, Jia, Z.
Deposit date:2009-06-02
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:X-ray crystal structure of human heme oxygenase-1 with (2R,4S)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-4[((5-trifluoromethylpyridin-2-yl)thio)methyl]-1,3-dioxolane: a novel, inducible binding mode.
J.Med.Chem., 52, 2009
2ZVU
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BU of 2zvu by Molmil
Crystal structure of rat heme oxygenase-1 in complex with ferrous verdoheme
Descriptor: 5-OXA-PROTOPORPHYRIN IX CONTAINING FE, FORMIC ACID, Heme oxygenase 1
Authors:Sato, H, Sugishima, M, Fukuyama, K, Noguchi, M.
Deposit date:2008-11-21
Release date:2009-02-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of rat haem oxygenase-1 in complex with ferrous verdohaem: presence of a hydrogen-bond network on the distal side
Biochem.J., 419, 2009
3CZY
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BU of 3czy by Molmil
Crystal Structure of Human Heme Oxygenase-1 in Complex with 1-(Adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone
Descriptor: 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Jia, Z, Rahman, M.N.
Deposit date:2008-04-30
Release date:2008-09-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:X-ray crystal structure of human heme oxygenase-1 in complex with 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone: a common binding mode for imidazole-based heme oxygenase-1 inhibitors.
J.Med.Chem., 51, 2008
2RGZ
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BU of 2rgz by Molmil
Ensemble refinement of the protein crystal structure of human heme oxygenase-2 C127A (HO-2) with bound heme
Descriptor: Heme oxygenase 2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Bianchetti, C.M, Bingman, C.A, Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2007-10-05
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Comparison of Apo- and Heme-bound Crystal Structures of a Truncated Human Heme Oxygenase-2.
J.Biol.Chem., 282, 2007
2QPP
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BU of 2qpp by Molmil
Crystal structure of human heme oxygenase-2 C127A (HO-2) with bound heme
Descriptor: Heme oxygenase 2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Bianchetti, C.M, Bingman, C.A, Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2007-07-24
Release date:2007-08-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Comparison of Apo- and Heme-bound Crystal Structures of a Truncated Human Heme Oxygenase-2.
J.Biol.Chem., 282, 2007
2Z68
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BU of 2z68 by Molmil
Crystal Structure Of An Artificial Metalloprotein: Cr[N-salicylidene-4-amino-3-hydroxyhydrocinnamic acid]/Wild Type Heme oxygenase
Descriptor: Heme oxygenase, SODIUM ION, SULFATE ION, ...
Authors:Yokoi, N, Unno, M, Ueno, T, Ikeda-Saito, M, Watanabe, Y.
Deposit date:2007-07-24
Release date:2007-08-28
Last modified:2024-09-18
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Ligand design for the improvement of stability of metal complex.protein hybrids.
Chem.Commun.(Camb.), 2008
2Q32
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BU of 2q32 by Molmil
Crystal structure of human heme oxygenase-2 C127A (HO-2)
Descriptor: Heme oxygenase 2, OXTOXYNOL-10
Authors:Bianchetti, C.M, Bingman, C.A, Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2007-05-29
Release date:2007-06-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Comparison of Apo- and Heme-bound Crystal Structures of a Truncated Human Heme Oxygenase-2.
J.Biol.Chem., 282, 2007
2E7E
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BU of 2e7e by Molmil
Bent-binding of cyanide to the heme iron in rat heme oxygenase-1
Descriptor: CYANIDE ION, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugishima, M, Fukuyama, K.
Deposit date:2007-01-09
Release date:2007-06-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Alternative cyanide-binding modes to the haem iron in haem oxygenase
Acta Crystallogr.,Sect.F, 63, 2007
2DY5
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BU of 2dy5 by Molmil
Crystal structure of rat heme oxygenase-1 in complex with heme and 2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolane
Descriptor: 1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE, CHLORIDE ION, Heme oxygenase 1, ...
Authors:Sugishima, M, Takahashi, H, Fukuyama, K.
Deposit date:2006-09-06
Release date:2007-05-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray crystallographic and biochemical characterization of the inhibitory action of an imidazole-dioxolane compound on heme oxygenase
Biochemistry, 46, 2007
1WZF
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BU of 1wzf by Molmil
Crystal Structure Of An Artificial Metalloprotein: Fe(10-COOH-Salophen)/Wild Type Heme oxygenase
Descriptor: GLYCEROL, Heme oxygenase, SULFATE ION, ...
Authors:Unno, M, Yokoi, N, Ueno, T, Watanabe, Y, Ikeda-Saito, M.
Deposit date:2005-03-04
Release date:2006-02-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Design of metal cofactors activated by a protein-protein electron transfer system.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1WZD
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BU of 1wzd by Molmil
Crystal Structure Of An Artificial Metalloprotein: Fe(10-CH2CH2COOH-Salophen)/Wild Type Heme oxygenase
Descriptor: GLYCEROL, Heme oxygenase, SULFATE ION, ...
Authors:Unno, M, Yokoi, N, Ueno, T, Watanabe, Y, Ikeda-Saito, M.
Deposit date:2005-03-04
Release date:2006-02-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Design of metal cofactors activated by a protein-protein electron transfer system.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1WZG
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BU of 1wzg by Molmil
Crystal Structure Of An Artificial Metalloprotein: Fe(Salophen)/Wild Type Heme oxygenase
Descriptor: 2,2'-[1,2-PHENYLENEBIS(NITRILOMETHYLIDYNE)]BIS[PHENOLATO]](2-)-N,N',O,O']-IRON, GLYCEROL, Heme oxygenase, ...
Authors:Unno, M, Yokoi, N, Ueno, T, Watanabe, Y, Ikeda-Saito, M.
Deposit date:2005-03-04
Release date:2006-02-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Design of metal cofactors activated by a protein-protein electron transfer system.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1XK2
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BU of 1xk2 by Molmil
NADPH- and Ascorbate-Supported Heme Oxygenase Reactions are Distinct. Regiospecificity of Heme Cleavage by the R183E Mutant
Descriptor: Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Wang, J, Lad, L, Poulos, T.L, Ortiz de montellano, P.R.
Deposit date:2004-09-26
Release date:2004-11-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Regiospecificity determinants of human heme oxygenase: differential NADPH- and ascorbate-dependent heme cleavage by the R183E mutant.
J.Biol.Chem., 280, 2005
1XK0
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BU of 1xk0 by Molmil
Crystal Structures of the G139A, G139A-NO and G143H Mutants of Human Heme Oxygenase-1
Descriptor: Heme oxygenase 1, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Lad, L, Koshkin, A, Ortiz de Montellano, P.R, Poulos, T.L.
Deposit date:2004-09-26
Release date:2005-12-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal structures of the G139A, G139A-NO and G143H mutants of human heme oxygenase-1. A finely tuned hydrogen-bonding network controls oxygenase versus peroxidase activity.
J.Biol.Inorg.Chem., 10, 2005
1XK3
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BU of 1xk3 by Molmil
NADPH- and Ascorbate-Supported Heme Oxygenase Reactions are Distinct. Regiospecificity of Heme Cleavage by the R183E Mutant
Descriptor: Heme oxygenase 1, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Wang, J, Lad, L, Poulos, T.L, Ortiz de montellano, P.R.
Deposit date:2004-09-26
Release date:2004-11-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Regiospecificity determinants of human heme oxygenase: differential NADPH- and ascorbate-dependent heme cleavage by the R183E mutant.
J.Biol.Chem., 280, 2005
1XK1
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BU of 1xk1 by Molmil
Crystal Structures of the G139A, G139A-NO and G143H Mutants of Human Heme Oxygenase-1
Descriptor: Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Lad, L, Ortiz de Montellano, P.R, Poulos, T.L.
Deposit date:2004-09-26
Release date:2005-12-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystal structures of the G139A, G139A-NO and G143H mutants of human heme oxygenase-1. A finely tuned hydrogen-bonding network controls oxygenase versus peroxidase activity.
J.Biol.Inorg.Chem., 10, 2005

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