3CZY
Crystal Structure of Human Heme Oxygenase-1 in Complex with 1-(Adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone
Summary for 3CZY
Entry DOI | 10.2210/pdb3czy/pdb |
Descriptor | Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone, ... (4 entities in total) |
Functional Keywords | heme oxygenase-1 inhibitor complex, endoplasmic reticulum, heme, iron, metal-binding, microsome, oxidoreductase, phosphoprotein, polymorphism |
Biological source | Homo sapiens (human) |
Cellular location | Microsome: P09601 |
Total number of polymer chains | 2 |
Total formula weight | 55518.87 |
Authors | Jia, Z.,Rahman, M.N. (deposition date: 2008-04-30, release date: 2008-09-30, Last modification date: 2023-08-30) |
Primary citation | Rahman, M.N.,Vlahakis, J.Z.,Szarek, W.A.,Nakatsu, K.,Jia, Z. X-ray crystal structure of human heme oxygenase-1 in complex with 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone: a common binding mode for imidazole-based heme oxygenase-1 inhibitors. J.Med.Chem., 51:5943-5952, 2008 Cited by PubMed: 18798608DOI: 10.1021/jm800505m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.54 Å) |
Structure validation
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