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5A1W
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BU of 5a1w by Molmil
The structure of the COPI coat linkage II
Descriptor: ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA, ...
Authors:Dodonova, S.O, Diestelkoetter-Bachert, P, von Appen, A, Hagen, W.J.H, Beck, R, Beck, M, Wieland, F, Briggs, J.A.G.
Deposit date:2015-05-06
Release date:2015-07-08
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
5A1X
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BU of 5a1x by Molmil
The structure of the COPI coat linkage III
Descriptor: ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA, ...
Authors:Dodonova, S.O, Diestelkoetter-Bachert, P, von Appen, A, Hagen, W.J.H, Beck, R, Beck, M, Wieland, F, Briggs, J.A.G.
Deposit date:2015-05-06
Release date:2015-07-08
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
5A1Y
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BU of 5a1y by Molmil
The structure of the COPI coat linkage IV
Descriptor: ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA, ...
Authors:Dodonova, S.O, Diestelkoetter-Bachert, P, von Appen, A, Hagen, W.J.H, Beck, R, Beck, M, Wieland, F, Briggs, J.A.G.
Deposit date:2015-05-06
Release date:2015-07-08
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (21 Å)
Cite:Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
5C7Z
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BU of 5c7z by Molmil
AP2 Mu2 adaptin C-terminal domain complexed with integrin alpha-4 peptide
Descriptor: AP-2 complex subunit mu, Integrin alpha-4
Authors:Owen, D.J, Evans, P.R, Wilson, T.A.
Deposit date:2015-06-25
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:AP2 Mu2 adaptin C-terminal domain complexed with integrin alpha-4 peptide
To Be Published
5FJW
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BU of 5fjw by Molmil
Yeast delta-COP-I mu-homology domain complexed with Dsl1 WxWx(MSE) peptide
Descriptor: COATOMER SUBUNIT DELTA, PROTEIN TRANSPORT PROTEIN DSL1
Authors:Suckling, R.J, Evans, P.R, Owen, D.J.
Deposit date:2015-10-13
Release date:2015-11-11
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for the Binding of Tryptophan-Based Motifs by Delta-Cop.
Proc.Natl.Acad.Sci.USA, 112, 2015
5FJX
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BU of 5fjx by Molmil
Yeast delta-COP-I mu-homology domain complexed with Gcs1 WxxF peptide
Descriptor: ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN GCS1, COATOMER SUBUNIT DELTA
Authors:Suckling, R.J, Evans, P.R, Owen, D.J.
Deposit date:2015-10-13
Release date:2015-11-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural Basis for the Binding of Tryptophan-Based Motifs by Delta-Cop.
Proc.Natl.Acad.Sci.USA, 112, 2015
5FJZ
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BU of 5fjz by Molmil
Yeast delta-COP-I mu-homology domain complexed with Dsl1 WxWxV peptide
Descriptor: COATOMER SUBUNIT DELTA, PROTEIN TRANSPORT PROTEIN DSL1
Authors:Suckling, R.J, Evans, P.R, Owen, D.J.
Deposit date:2015-10-14
Release date:2015-11-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for the Binding of Tryptophan-Based Motifs by Delta-Cop.
Proc.Natl.Acad.Sci.USA, 112, 2015
5FK0
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BU of 5fk0 by Molmil
Yeast delta-COP-I mu-homology domain
Descriptor: CALCIUM ION, COATOMER SUBUNIT DELTA
Authors:Suckling, R.J, Evans, P.R, Owen, D.J.
Deposit date:2015-10-14
Release date:2015-11-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for the Binding of Tryptophan-Based Motifs by Delta-Cop.
Proc.Natl.Acad.Sci.USA, 112, 2015
5FPI
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BU of 5fpi by Molmil
Mu2 adaptin subunit of the AP2 adaptor (C-terminal domain) complexed with Integrin alpha4 internalisation peptide QYKSILQE
Descriptor: AP-2 COMPLEX SUBUNIT MU, INTEGRIN ALPHA-4 SUBUNIT
Authors:Owen, D.J, Evans, P.R, Ivaska, J.
Deposit date:2015-11-30
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Selective Integrin Endocytosis is Driven by Alpha Chain:Ap2 Interactions
Nat.Struct.Mol.Biol., 23, 2016
5NZR
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BU of 5nzr by Molmil
The structure of the COPI coat leaf
Descriptor: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZS
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BU of 5nzs by Molmil
The structure of the COPI coat leaf in complex with the ArfGAP2 uncoating factor
Descriptor: ADP-ribosylation factor 1, ADP-ribosylation factor GTPase-activating protein 2, Coatomer subunit alpha, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZT
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BU of 5nzt by Molmil
The structure of the COPI coat linkage I
Descriptor: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (17 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZU
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BU of 5nzu by Molmil
The structure of the COPI coat linkage II
Descriptor: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (15 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZV
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BU of 5nzv by Molmil
The structure of the COPI coat linkage IV
Descriptor: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (17.299999 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5WRK
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BU of 5wrk by Molmil
Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y608 peptide
Descriptor: AP-2 complex subunit mu, Insulin receptor substrate 1, NICKEL (II) ION
Authors:Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S.
Deposit date:2016-12-02
Release date:2017-12-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Elife, 7, 2018
5WRL
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BU of 5wrl by Molmil
Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y628 peptide
Descriptor: AP-2 complex subunit mu, Insulin receptor substrate 1
Authors:Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S.
Deposit date:2016-12-02
Release date:2017-12-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.095 Å)
Cite:IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Elife, 7, 2018
5WRM
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BU of 5wrm by Molmil
Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y658 peptide
Descriptor: AP-2 complex subunit mu, Insulin receptor substrate 1
Authors:Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S.
Deposit date:2016-12-02
Release date:2017-12-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.597 Å)
Cite:IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Elife, 7, 2018
6BNT
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BU of 6bnt by Molmil
Crystal structure of AP2 mu1 adaptin C-terminal domain with IRS-1 peptide
Descriptor: AP-2 complex subunit mu, Insulin receptor substrate 1
Authors:Kikuchi, S, Choi, E, Yu, H.
Deposit date:2017-11-17
Release date:2018-11-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling.
Nat Commun, 10, 2019
6CM9
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BU of 6cm9 by Molmil
Structure of the cargo bound AP-1:Arf1:tetherin-Nef closed trimer monomeric subunit
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H.
Deposit date:2018-03-03
Release date:2018-08-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
6CRI
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BU of 6cri by Molmil
Structure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimer
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Morris, K.L, Buffalo, C.Z, Hurley, J.H.
Deposit date:2018-03-18
Release date:2018-08-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
6D83
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BU of 6d83 by Molmil
Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer monomeric subunit
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Buffalo, C.Z, Morris, K.L, Hurley, J.H.
Deposit date:2018-04-25
Release date:2018-08-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.27 Å)
Cite:HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
6D84
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BU of 6d84 by Molmil
Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Buffalo, C.Z, Morris, K.L, Hurley, J.H.
Deposit date:2018-04-25
Release date:2018-08-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.72 Å)
Cite:HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
6DFF
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BU of 6dff by Molmil
Structure of the cargo bound AP-1:Arf1:tetherin-Nef monomer
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H.
Deposit date:2018-05-14
Release date:2018-08-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
6OWO
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BU of 6owo by Molmil
CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 CORE BOUND TO NECAP
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Partlow, E.A, Baker, R.W, Beacham, G.M, Chappie, J.S, Leschziner, A.E, Hollopeter, G.
Deposit date:2019-05-10
Release date:2019-09-11
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex.
Elife, 8, 2019
6OXL
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BU of 6oxl by Molmil
CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 (mu E302K) BOUND TO NECAP IN THE PRESENCE OF SS DNA
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Partlow, E.A, Baker, R.W, Beacham, G.M, Chappie, J, Leschziner, A.E, Hollopeter, G.
Deposit date:2019-05-13
Release date:2019-09-11
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex.
Elife, 8, 2019

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