5FPI
Mu2 adaptin subunit of the AP2 adaptor (C-terminal domain) complexed with Integrin alpha4 internalisation peptide QYKSILQE
Summary for 5FPI
Entry DOI | 10.2210/pdb5fpi/pdb |
Descriptor | AP-2 COMPLEX SUBUNIT MU, INTEGRIN ALPHA-4 SUBUNIT (3 entities in total) |
Functional Keywords | endocytosis, clathrin adaptor |
Biological source | RATTUS NORVEGICUS (NORWAY RAT) More |
Cellular location | Cell membrane : P84092 |
Total number of polymer chains | 2 |
Total formula weight | 52053.25 |
Authors | Owen, D.J.,Evans, P.R.,Ivaska, J. (deposition date: 2015-11-30, release date: 2016-01-20, Last modification date: 2024-01-10) |
Primary citation | De Franceschi, N.,Arjonen, A.,Elkhatib, N.,Denessiouk, K.,Wrobel, A.G.,Wilson, T.A.,Pouwels, J.,Montagnac, G.,Owen, D.J.,Ivaska, J. Selective Integrin Endocytosis is Driven by Alpha Chain:Ap2 Interactions Nat.Struct.Mol.Biol., 23:172-, 2016 Cited by PubMed: 26779610DOI: 10.1038/NSMB.3161 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.77 Å) |
Structure validation
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