5WRL
Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y628 peptide
Summary for 5WRL
Entry DOI | 10.2210/pdb5wrl/pdb |
Related | 5WRK 5WRM |
Descriptor | AP-2 complex subunit mu, Insulin receptor substrate 1 (2 entities in total) |
Functional Keywords | endocytosis, clathrin adaptor ap-2 complex subunit, peptide complex |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 2 |
Total formula weight | 32767.45 |
Authors | Yoneyama, Y.,Niwa, H.,Umehara, T.,Yokoyama, S.,Hakuno, F.,Takahashi, S. (deposition date: 2016-12-02, release date: 2017-12-06, Last modification date: 2023-11-08) |
Primary citation | Yoneyama, Y.,Lanzerstorfer, P.,Niwa, H.,Umehara, T.,Shibano, T.,Yokoyama, S.,Chida, K.,Weghuber, J.,Hakuno, F.,Takahashi, S.I. IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling Elife, 7:-, 2018 Cited by PubMed: 29661273DOI: 10.7554/eLife.32893 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.095 Å) |
Structure validation
Download full validation report