PDB: 2558 resultsInfo pagesStatus searchChemie searchBIRD

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8WXU	Structure of WDR5 in complex with WIN motif containing MBD3C C44S/R45E/V46G Descriptor: MBD3C, WD repeat-containing protein 5 Authors: Xu, L, Yang, Y. Deposit date: 2023-10-30 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (2.37 Å) Cite: Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode. J.Biol.Chem., 300, 2024
8WXR	Structure of WDR5 in complex with WIN motif containing MBD3C F47A Descriptor: MBD3C, WD repeat-containing protein 5 Authors: Xu, L, Yang, Y. Deposit date: 2023-10-30 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode. J.Biol.Chem., 300, 2024
8WXV	Structure of WDR5 in complex with WIN motif containing SET1B Descriptor: SET1B, WD repeat-containing protein 5 Authors: Xu, L, Yang, Y. Deposit date: 2023-10-30 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode. J.Biol.Chem., 300, 2024
8WXX	Structure of WDR5 in complex with WIN motif containing SET1B E1750R/G1751V Descriptor: SET1B, WD repeat-containing protein 5 Authors: Xu, L, Yang, Y. Deposit date: 2023-10-30 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode. J.Biol.Chem., 300, 2024
8W3V	Crystal structure of human WDR41 Descriptor: WD repeat-containing protein 41 Authors: Hutchinson, A, Dong, A, Li, Y, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) Deposit date: 2024-02-22 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of human WDR41 To be published
7WVK	Crystal structure of human WDR5 in complex with compound 19 Descriptor: 1,2-ETHANEDIOL, 1-[2,5-bis(chloranyl)phenyl]sulfonylbenzimidazole, GLYCEROL, ... Authors: Han, Q.L, Zhang, X.L, Wang, L, Ren, P.X, Cao, Y, Li, K, Bai, F. Deposit date: 2022-02-10 Release date: 2022-10-19 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Discovery, evaluation and mechanism study of WDR5-targeted small molecular inhibitors for neuroblastoma. Acta Pharmacol.Sin., 44, 2023
8HMX	WDR5 in complex with histone H3Q5his peptide Descriptor: WD repeat-containing protein 5, histone H3Q5his peptide Authors: Li, H.T, Zhao, S, Wang, H.F. Deposit date: 2022-12-06 Release date: 2023-12-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: WDR5 in complex with histone H3Q5his peptide To Be Published
8HQX	The complex structure of COPI cargo sorting module with TAT-WDM peptide Descriptor: Coatomer subunit beta', TAT-WDM KxKxx motif Authors: Ma, W.F, Nan, Y.N, Yang, M.R, Li, Y.Q. Deposit date: 2022-12-14 Release date: 2023-12-20 Method: X-RAY DIFFRACTION (1.538 Å) Cite: The complex structure of COPI cargo sorting module with TAT-WDM peptide To Be Published
8HQT	The complex structure of COPI cargo sorting module with SARS-CoV-2 Spike KxHxx sorting motif Descriptor: Coatomer subunit beta', SARS-CoV-2 Spike KxHxx motif Authors: Ma, W.F, Nan, Y.N, Yang, M.R, Li, Y.Q. Deposit date: 2022-12-14 Release date: 2023-12-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Tighter ER retention of SARS-CoV-2 Omicron spike caused by a constellation of folding disruptive mutations To Be Published
8HQV	The complex structure of COPI cargo sorting module with HCoV-OC43 Spike KTSHxx sorting motif Descriptor: Coatomer subunit beta', HCoV-OC43 Spike KTSHxx sorting motif Authors: Ma, W.F, Nan, Y.N, Yang, M.R, Li, Y.Q. Deposit date: 2022-12-14 Release date: 2023-12-20 Method: X-RAY DIFFRACTION (1.398 Å) Cite: Tighter ER retention of SARS-CoV-2 Omicron spike caused by a constellation of folding disruptive mutations To Be Published
8HQW	The complex structure of COPI cargo sorting module with MHV Spike Hxx sorting motif Descriptor: Coatomer subunit beta',MHV Spike Hxx sorting motif Authors: Ma, W.F, Nan, Y.N, Yang, M.R, Li, Y.Q. Deposit date: 2022-12-14 Release date: 2023-12-20 Method: X-RAY DIFFRACTION (1.405 Å) Cite: Tighter ER retention of SARS-CoV-2 Omicron spike caused by a constellation of folding disruptive mutations To Be Published
2AQ5	Crystal Structure of Murine Coronin-1 Descriptor: Coronin-1A Authors: Appleton, B.A, Wu, P, Wiesmann, C. Deposit date: 2005-08-17 Release date: 2005-12-06 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: The crystal structure of murine coronin-1: a regulator of actin cytoskeletal dynamics in lymphocytes. Structure, 14, 2006
2XU7	Structural basis for RbAp48 binding to FOG-1 Descriptor: HISTONE-BINDING PROTEIN RBBP4, TETRAETHYLENE GLYCOL, ZINC FINGER PROTEIN ZFPM1 Authors: Lejon, S, Thong, S.Y, Murthy, A, Blobel, G.A, Mackay, J.P, Murzina, N.V, Laue, E.D. Deposit date: 2010-10-15 Release date: 2010-11-03 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Insights Into Association of the Nurd Complex with Fog-1 from the Crystal Structure of an Rbap48-Fog- 1 Complex. J.Biol.Chem., 286, 2011
2TRC	PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX Descriptor: GADOLINIUM ATOM, PHOSDUCIN, TRANSDUCIN Authors: Gaudet, R, Bohm, A, Sigler, P.B. Deposit date: 1997-01-06 Release date: 1997-06-05 Last modified: 2019-08-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin. Cell(Cambridge,Mass.), 87, 1996
2QXV	Structural basis of EZH2 recognition by EED Descriptor: Embryonic ectoderm development, Enhancer of zeste homolog 2 Authors: Han, Z. Deposit date: 2007-08-13 Release date: 2007-08-28 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Structural basis of EZH2 recognition by EED Structure, 15, 2007
1A0R	HETEROTRIMERIC COMPLEX OF PHOSDUCIN/TRANSDUCIN BETA-GAMMA Descriptor: FARNESYL, PHOSDUCIN, TRANSDUCIN (BETA SUBUNIT), ... Authors: Loew, A, Ho, Y.-K, Blundell, T.L, Bax, B. Deposit date: 1997-12-05 Release date: 1998-12-30 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Phosducin induces a structural change in transducin beta gamma. Structure, 6, 1998
1B9Y	STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN BETA-GAMMA Descriptor: GADOLINIUM ATOM, PROTEIN (PHOSDUCIN), PROTEIN (TRANSDUCIN) Authors: Gaudet, R, Sigler, P.B. Deposit date: 1999-02-16 Release date: 1999-02-23 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (3 Å) Cite: A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin. Mol.Cell, 3, 1999
1B9X	STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN Descriptor: GADOLINIUM ATOM, PROTEIN (PHOSDUCIN), PROTEIN (TRANSDUCIN) Authors: Gaudet, R, Sigler, P.B. Deposit date: 1999-02-16 Release date: 1999-02-23 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (3 Å) Cite: A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin. Mol.Cell, 3, 1999
1VYH	PAF-AH Holoenzyme: Lis1/Alfa2 Descriptor: PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB ALPHA SUBUNIT, PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB BETA SUBUNIT Authors: Tarricone, C, Perrina, F, Monzani, S, Massimiliano, L, Knapp, S, Tsai, L.-H, Derewenda, Z.S, Musacchio, A. Deposit date: 2004-04-30 Release date: 2005-05-26 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Coupling Paf Signaling to Dynein Regulation: Structure of Lis1 in Complex with Paf-Acetylhydrolase. Neuron, 44, 2004
1XHM	The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1, SIGK Peptide Authors: Davis, T.L, Bonacci, T.M, Smrcka, A.V, Sprang, S.R. Deposit date: 2004-09-20 Release date: 2005-08-09 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural and Molecular Characterization of a Preferred Protein Interaction Surface on G Protein betagamma Subunits. Biochemistry, 44, 2005
5FA5	Crystal Structure of PRMT5:MEP50 in complex with MTA and H4 peptide Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, Histone H4, Methylosome protein 50, ... Authors: Sprague, E.R, McNamara, J.T. Deposit date: 2015-12-10 Release date: 2016-02-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5. Science, 351, 2016
5FLC	Architecture of human mTOR Complex 1 - 5.9 Angstrom reconstruction Descriptor: FKBP, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, REGULATORY-ASSOCIATED PROTEIN OF MTOR, ... Authors: Aylett, C.H.S, Sauer, E, Imseng, S, Boehringer, D, Hall, M.N, Ban, N, Maier, T. Deposit date: 2015-10-23 Release date: 2015-12-30 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (5.9 Å) Cite: Architecture of Human Mtor Complex 1 Science, 351, 2016
1GG2	G PROTEIN HETEROTRIMER MUTANT GI_ALPHA_1(G203A) BETA_1 GAMMA_2 WITH GDP BOUND Descriptor: G PROTEIN GI ALPHA 1, G PROTEIN GI BETA 1, G PROTEIN GI GAMMA 2, ... Authors: Wall, M.A, Sprang, S.R. Deposit date: 1996-11-13 Release date: 1997-02-12 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2. Cell(Cambridge,Mass.), 83, 1995
1GOT	HETEROTRIMERIC COMPLEX OF A GT-ALPHA/GI-ALPHA CHIMERA AND THE GT-BETA-GAMMA SUBUNITS Descriptor: GT-ALPHA/GI-ALPHA CHIMERA, GT-BETA, GT-GAMMA, ... Authors: Lambright, D.G, Sondek, J, Bohm, A, Skiba, N.P, Hamm, H.E, Sigler, P.B. Deposit date: 1996-08-07 Release date: 1997-03-12 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: The 2.0 A crystal structure of a heterotrimeric G protein. Nature, 379, 1996
1GP2	G PROTEIN HETEROTRIMER GI_ALPHA_1 BETA_1 GAMMA_2 WITH GDP BOUND Descriptor: G PROTEIN GI ALPHA 1, G PROTEIN GI BETA 1, G PROTEIN GI GAMMA 2, ... Authors: Wall, M.A, Sprang, S.R. Deposit date: 1996-11-13 Release date: 1997-02-12 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2. Cell(Cambridge,Mass.), 83, 1995

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