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8HQV

The complex structure of COPI cargo sorting module with HCoV-OC43 Spike KTSHxx sorting motif

Summary for 8HQV
Entry DOI10.2210/pdb8hqv/pdb
DescriptorCoatomer subunit beta', HCoV-OC43 Spike KTSHxx sorting motif (3 entities in total)
Functional Keywordshcov-oc43, spike, copi vesicle, ktshxx motif, retention signal, transport protein
Biological sourceSaccharomyces cerevisiae (strain YJM789) (Baker's yeast)
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Total number of polymer chains2
Total formula weight35451.91
Authors
Ma, W.F.,Nan, Y.N.,Yang, M.R.,Li, Y.Q. (deposition date: 2022-12-14, release date: 2023-12-20)
Primary citationLi, Y.Q.,Yang, M.R.,Nan, Y.N.,Wang, J.M.,Guo, J.J.,He, P.F.,Dai, W.X.,Zhou, S.Q.,Wang, S.J.,Zhang, Y.,Ma, W.F.
Tighter ER retention of SARS-CoV-2 Omicron spike caused by a constellation of folding disruptive mutations
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.398 Å)
Structure validation

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