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2CXC
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Crystal structure of archaeal transcription termination factor NusA
分子名称: NusA
著者Shibata, R, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-06-28
公開日2005-12-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure and RNA-binding analysis of the archaeal transcription factor NusA
Biochem.Biophys.Res.Commun., 355, 2007
2CY1
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Crystal structure of APE1850
分子名称: NusA protein homolog
著者Shibata, R, Bessho, Y, Umehara, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-04
公開日2006-01-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystallization of the archaeal transcription termination factor NusA: a significant decrease in twinning under microgravity conditions
Acta Crystallogr.,Sect.F, 63, 2007
1WH9
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Solution structure of the KH domain of human ribosomal protein S3
分子名称: 40S ribosomal protein S3
著者Nameki, N, Tomizawa, T, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-28
公開日2004-11-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the KH domain of human ribosomal protein S3
To be Published
4D5L
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BU of 4d5l by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
分子名称: 18S RRNA 2, 40S RIBOSOMAL PROTEIN ES1, 40S RIBOSOMAL PROTEIN ES10, ...
著者Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
登録日2014-11-05
公開日2015-02-04
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
5WIT
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with pikromycin and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution
分子名称: (3R,5R,6S,7S,9R,11E,13S,14R)-14-ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-2,4,10-trioxo-1-oxacyclotetradec-11-en-6-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Almutairi, M.M, Svetlov, M.S, Hansen, D.A, Khabibullina, N.F, Klepacki, D, Kang, H.Y, Sherman, D.H, Vazquez-Laslop, N, Polikanov, Y.S, Mankin, A.S.
登録日2017-07-20
公開日2018-02-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins.
Nucleic Acids Res., 45, 2017
3R9W
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Crystal structure of Era in complex with MgGDPNP and nucleotides 1506-1542 of 16S ribosomal RNA
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, CALCIUM ION, ...
著者Tu, C, Ji, X.
登録日2011-03-26
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
8CAH
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Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2023-01-24
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
4Y4O
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Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to protein Y (YfiA) at 2.3A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Polikanov, Y.S, Melnikov, S.V, Soll, D, Steitz, T.A.
登録日2015-02-10
公開日2015-03-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Nat.Struct.Mol.Biol., 22, 2015
6ENF
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BU of 6enf by Molmil
Cryo-EM structure of a polyproline-stalled ribosome in the absence of EF-P
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Huter, P, Arenz, S, Wilson, D.N.
登録日2017-10-04
公開日2017-11-22
最終更新日2018-01-31
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
Mol. Cell, 68, 2017
6FAI
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BU of 6fai by Molmil
Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit
分子名称: 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Scaiola, A, Pena, C, Weisser, M, Boehringer, D, Leibundgut, M, Klingauf-Nerurkar, P, Gerhardy, S, Panse, V.G, Ban, N.
登録日2017-12-15
公開日2018-02-28
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit.
EMBO J., 37, 2018
1HNW
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STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH TETRACYCLINE
分子名称: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Brodersen, D.E, Clemons Jr, W.M, Carter, A.P, Morgan-Warren, R, Wimberly, B.T, Ramakrishnan, V.
登録日2000-12-08
公開日2001-02-21
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit.
Cell(Cambridge,Mass.), 103, 2000
1HR0
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CRYSTAL STRUCTURE OF INITIATION FACTOR IF1 BOUND TO THE 30S RIBOSOMAL SUBUNIT
分子名称: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Morgan-Warren, R.J, Wimberly, B.T, Ramakrishnan, V.
登録日2000-12-20
公開日2001-01-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of an initiation factor bound to the 30S ribosomal subunit.
Science, 291, 2001
2F4V
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30S ribosome + designer antibiotic
分子名称: (2R)-4-AMINO-N-{(1R,2S,3R,4R,5S)-5-AMINO-2-{2-[(2-AMINOETHYL)AMINO]ETHOXY}-4-[(2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-3-HYDROXYCYCLOHEXYL}-2-HYDROXYBUTANAMIDE, (2S,4S,4AR,5AS,6S,11R,11AS,12R,12AR)-7-CHLORO-4-(DIMETHYLAMINO)-6,10,11,12-TETRAHYDROXY-1,3-DIOXO-1,2,3,4,4A,5,5A,6,11,11A,12,12A-DODECAHYDROTETRACENE-2-CARBOXAMIDE, 16S ribosomal RNA, ...
著者Murray, J.B, Meroueh, S.O, Russell, R.J, Lentzen, G, Haddad, J, Mobashery, S.
登録日2005-11-24
公開日2006-07-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Interactions of designer antibiotics and the bacterial ribosome aminoacyl-tRNA site
Chem.Biol., 13, 2006
3T1Y
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Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA Lysine 3 (TRNALYS3) bound to an mRNA with an AAG-codon in the A-site and paromomycin
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F.
登録日2011-07-22
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism.
J.Mol.Biol., 416, 2012
2HHH
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Crystal structure of kasugamycin bound to the 30S ribosomal subunit
分子名称: (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S ribosomal RNA, 30S ribosomal protein S10, ...
著者Schluenzen, F.
登録日2006-06-28
公開日2006-09-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.
Nat.Struct.Mol.Biol., 13, 2006
3T1H
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Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA lysine 3 (tRNALys3) bound to an mRNA with an AAA-codon in the A-site and Paromomycin
分子名称: 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F.
登録日2011-07-21
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism.
J.Mol.Biol., 416, 2012
1EGA
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BU of 1ega by Molmil
CRYSTAL STRUCTURE OF A WIDELY CONSERVED GTPASE ERA
分子名称: PROTEIN (GTP-BINDING PROTEIN ERA), SULFATE ION
著者Chen, X, Ji, X.
登録日1998-12-01
公開日1999-07-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of ERA: a GTPase-dependent cell cycle regulator containing an RNA binding motif.
Proc.Natl.Acad.Sci.USA, 96, 1999
1FJG
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BU of 1fjg by Molmil
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTICS STREPTOMYCIN, SPECTINOMYCIN, AND PAROMOMYCIN
分子名称: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Wimberly, B.T, Morgan-Warren, R.J, Ramakrishnan, V.
登録日2000-08-08
公開日2000-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
Nature, 407, 2000
3OTO
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Crystal Structure of the 30S ribosomal subunit from a KsgA mutant of Thermus thermophilus (HB8)
分子名称: 16S rRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Demirci, H, Murphy IV, F, Belardinelli, R, Kelley, A.C, Ramakrishnan, V, Gregory, S.T, Dahlberg, A.E, Jogl, G.
登録日2010-09-13
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.69 Å)
主引用文献Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function.
Rna, 16, 2010
3R9X
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BU of 3r9x by Molmil
Crystal structure of Era in complex with MgGDPNP, nucleotides 1506-1542 of 16S ribosomal RNA, and KsgA
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, GTPase Era, ...
著者Tu, C, Ji, X.
登録日2011-03-26
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
1VVJ
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Crystal Structure of Frameshift Suppressor tRNA SufA6 bound to Codon CCC-G on the Ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Maehigashi, T, Dunkle, J.A, Dunham, C.M.
登録日2013-05-24
公開日2014-08-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.440001 Å)
主引用文献Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
1VY6
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Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Puromycin in the A site and acylated tRNA in the P site.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Polikanov, Y.S, Steitz, T.A, Innis, C.A.
登録日2014-05-13
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
5FLX
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Mammalian 40S HCV-IRES complex
分子名称: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ...
著者Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T.
登録日2015-10-28
公開日2015-12-23
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA.
Embo J., 34, 2015
5FDU
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Crystal structure of the Metalnikowin I antimicrobial peptide bound to the Thermus thermophilus 70S ribosome
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Seefeldt, A.C, Graf, M, Perebaskine, N, Nguyen, F, Arenz, S, Mardirossian, M, Scocchi, M, Wilson, D.N, Innis, C.A.
登録日2015-12-16
公開日2016-01-27
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.
Nucleic Acids Res., 44, 2016
6I7V
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Ribosomal protein paralogs bL31 and bL36
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
著者Pulk, A, Cate, J.H.D, Remme, J, Lilleorg, S, Reier, K, Peil, L, Liiv, A, Tammsalu, T.
登録日2018-11-19
公開日2018-12-05
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Bacterial ribosome heterogeneity: Changes in ribosomal protein composition during transition into stationary growth phase.
Biochimie, 156, 2018

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