4MHL
| The crystal structure of human interleukin-11 | 分子名称: | FORMAMIDE, Interleukin-11, SULFATE ION | 著者 | Griffin, M.D.W. | 登録日 | 2013-08-29 | 公開日 | 2014-09-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | The structure of human interleukin-11 reveals receptor-binding site features and structural differences from interleukin-6. Acta Crystallogr.,Sect.D, 70, 2014
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6O4O
| The structure of human interleukin 11 | 分子名称: | CHLORIDE ION, Interleukin-11, SULFATE ION | 著者 | Metcalfe, R.D, Griffin, M.D.W. | 登録日 | 2019-02-28 | 公開日 | 2020-05-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | The structure of the extracellular domains of human interleukin 11 alpha receptor reveals mechanisms of cytokine engagement. J.Biol.Chem., 295, 2020
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8DPS
| The structure of the interleukin 11 signalling complex, truncated gp130 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... | 著者 | Metcalfe, R.D, Hanssen, E, Griffin, M.D.W. | 登録日 | 2022-07-17 | 公開日 | 2023-11-29 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14, 2023
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8DPT
| The structure of the IL-11 signalling complex, with full-length extracellular gp130 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... | 著者 | Metcalfe, R.D, Hanssen, E, Griffin, M.D.W. | 登録日 | 2022-07-17 | 公開日 | 2023-11-29 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14, 2023
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8DPU
| The crystal structure of the IL-11 signalling complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... | 著者 | Metcalfe, R.D, Aizel, K, Griffin, M.D.W. | 登録日 | 2022-07-17 | 公開日 | 2023-11-29 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.78 Å) | 主引用文献 | Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14, 2023
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8DPV
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8DPW
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8QY4
| Structure of interleukin 11 (gp130 P496L mutant). | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... | 著者 | Gardner, S, Bubeck, D, Jin, Y. | 登録日 | 2023-10-25 | 公開日 | 2024-02-21 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency. Nat Commun, 15, 2024
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