Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3WGW
DownloadVisualize
BU of 3wgw by Molmil
Structure of PCNA bound to a small molecule inhibitor
分子名称: 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, Proliferating cell nuclear antigen, SULFATE ION
著者Hashimoto, H.
登録日2013-08-12
公開日2014-02-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin.
J.Biol.Chem., 289, 2014
8COB
DownloadVisualize
BU of 8cob by Molmil
Crystal structure of human PCNA in complex with ERCC6L2 PIP box peptide
分子名称: DNA excision repair protein ERCC-6-like 2, Proliferating cell nuclear antigen
著者Ariza, A.
登録日2023-02-27
公開日2023-04-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献ERCC6L2 mitigates replication stress and promotes centromere stability.
Cell Rep, 42, 2023
3L0X
DownloadVisualize
BU of 3l0x by Molmil
Structure of split yeast PCNA
分子名称: Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-12-10
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
6WAC
DownloadVisualize
BU of 6wac by Molmil
FF248-249AA PCNA mutant defective in BIR
分子名称: Proliferating cell nuclear antigen
著者Ripley, B.M, Washington, M.T.
登録日2020-03-25
公開日2020-09-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural analysis of PCNA mutant proteins defective in BIR, FF248-249AA and R80A
To be Published
4CS5
DownloadVisualize
BU of 4cs5 by Molmil
Crystal Structure of PCNA from Litopenaeus vannamei
分子名称: PROLIFERATING CELL NUCLEAR ANTIGEN
著者Carrasco-Miranda, J.S, Lopez-Zavala, A.A, De-La-Mora, E, Rudino-Pinera, E, Brieba, L.G, Sotelo-Mundo, R.R.
登録日2014-03-04
公開日2014-04-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of the Shrimp Proliferating Cell Nuclear Antigen: Structural Complementarity with Wssv DNA Polymerase Pip-Box.
Plos One, 9, 2014
1AXC
DownloadVisualize
BU of 1axc by Molmil
HUMAN PCNA
分子名称: P21/WAF1, PCNA
著者Gulbis, J.M, Kuriyan, J.
登録日1997-10-14
公開日1998-01-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA.
Cell(Cambridge,Mass.), 87, 1996
4RJF
DownloadVisualize
BU of 4rjf by Molmil
Crystal structure of the human sliding clamp at 2.0 angstrom resolution
分子名称: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen
著者Kroker, A.J, Bruning, J.B.
登録日2014-10-09
公開日2015-08-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.0072 Å)
主引用文献p21 Exploits Residue Tyr151 as a Tether for High-Affinity PCNA Binding.
Biochemistry, 54, 2015
6O09
DownloadVisualize
BU of 6o09 by Molmil
Structure of AtPCNA in complex with the PIP motif of ATXR6
分子名称: Proliferating cellular nuclear antigen 1, Uncharacterized protein
著者Couture, J.F, Davarinejad, H.
登録日2019-02-15
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献ATXR5/6 Forms Alternative Protein Complexes with PCNA and the Nucleosome Core Particle.
J. Mol. Biol., 431, 2019
8B8T
DownloadVisualize
BU of 8b8t by Molmil
Open conformation of the complex of DNA ligase I on PCNA and DNA in the presence of ATP
分子名称: DNA ligase 1, Proliferating cell nuclear antigen
著者Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A.
登録日2022-10-05
公開日2023-01-11
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
4D2G
DownloadVisualize
BU of 4d2g by Molmil
Crystal structure of human PCNA in complex with p15 peptide
分子名称: P15, PROLIFERATING CELL NUCLEAR ANTIGEN
著者DeBiasio, A, Ibanez, A, Mortuza, G, Molina, R, Cordeiro, T.N, Castillo, F, Villate, M, Merino, N, Lelli, M, Diercks, T, Luque, I, Bernardo, P, Montoya, G, Blanco, F.J.
登録日2014-05-09
公開日2015-03-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair.
Nat.Commun., 6, 2015
7WP3
DownloadVisualize
BU of 7wp3 by Molmil
Crystal structure of the complex of proliferating cell nuclear antigen (PCNA) from Leishmania donovani with 1,5-Bis (4-amidinophenoxy) pentane (PNT) at 2.95 A resolution
分子名称: 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, Proliferating cell nuclear antigen
著者Ahmad, M.I, Yadav, S.P, Singh, P.K, Sharma, P, Kaur, P, Sharma, S, Singh, T.P.
登録日2022-01-22
公開日2022-06-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.954 Å)
主引用文献Crystal structure of the complex of proliferating cell nuclear antigen (PCNA) from Leishmania donovani with 1,5-Bis (4-amidinophenoxy) pentane (PNT) at 2.95 A resolution
To Be Published
1GE8
DownloadVisualize
BU of 1ge8 by Molmil
PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) HOMOLOG FROM PYROCOCCUS FURIOSUS
分子名称: PROLIFERATION CELL NUCLEAR ANTIGEN
著者Matsumiya, S, Ishino, Y, Morikawa, K.
登録日2000-10-18
公開日2001-01-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of an archaeal DNA sliding clamp: proliferating cell nuclear antigen from Pyrococcus furiosus.
Protein Sci., 10, 2001
5T9D
DownloadVisualize
BU of 5t9d by Molmil
Structure of PCNA acetylated on K20
分子名称: Proliferating cell nuclear antigen
著者Couture, J.F, Tremblay, V, Brunzelle, J.S.
登録日2016-09-09
公開日2017-04-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献Structure of PCNA acetylated on K20
To Be Published
5MLO
DownloadVisualize
BU of 5mlo by Molmil
Crystal structure of human PCNA in complex with ZRANB3 PIP box peptide
分子名称: Proliferating cell nuclear antigen, SODIUM ION, ZRANB3 PIP box peptide
著者Ariza, A.
登録日2016-12-07
公開日2017-06-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural insights into the function of ZRANB3 in replication stress response.
Nat Commun, 8, 2017
7EP8
DownloadVisualize
BU of 7ep8 by Molmil
Crystal structure of PCNA from Neurospora crassa
分子名称: Proliferating cell nuclear antigen
著者Sundaram, R, Vasudevan, D.
登録日2021-04-26
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Interdomain connecting loop and J loop structures determine cross-species compatibility of PCNA.
J.Biol.Chem., 297, 2021
6W9W
DownloadVisualize
BU of 6w9w by Molmil
R80A PCNA mutant defective in BIR
分子名称: Proliferating cell nuclear antigen
著者Ripley, B.M, Washington, M.T.
登録日2020-03-23
公開日2020-09-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural analysis of PCNA mutant proteins defective in BIR, FF248-249AA and R80A
To be Published
5MOM
DownloadVisualize
BU of 5mom by Molmil
Crystal Structure of PCNA encoding the hypomorphic mutation S228I
分子名称: Proliferating cell nuclear antigen
著者Biasutto, A.J, Mancini, E.J, Green, C.M, Wilson, R.H.C.
登録日2016-12-14
公開日2017-01-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions.
DNA Repair (Amst.), 50, 2017
5MLW
DownloadVisualize
BU of 5mlw by Molmil
Crystal structure of human PCNA in complex with ZRANB3 APIM motif peptide
分子名称: APIM motif peptide, Proliferating cell nuclear antigen, SULFATE ION
著者Ariza, A.
登録日2016-12-07
公開日2017-06-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural insights into the function of ZRANB3 in replication stress response.
Nat Commun, 8, 2017
5MAV
DownloadVisualize
BU of 5mav by Molmil
Crystal structure of human PCNA in complex with PARG (poly(ADP-ribose) glycohydrolase) peptide.
分子名称: Poly (ADP-ribose) glycohydrolase, Proliferating cell nuclear antigen
著者Grishkovskaya, I, Djinovic-Carugo, K, Slade, D.
登録日2016-11-06
公開日2017-08-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.575 Å)
主引用文献A novel non-canonical PIP-box mediates PARG interaction with PCNA.
Nucleic Acids Res., 45, 2017
6FCM
DownloadVisualize
BU of 6fcm by Molmil
Crystal structure of human PCNA
分子名称: Proliferating cell nuclear antigen
著者Housset, D, Frachet, P.
登録日2017-12-20
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.
J.Exp.Med., 216, 2019
6FCN
DownloadVisualize
BU of 6fcn by Molmil
Crystal structure of human PCNA soaked with p47phox(106-127) peptide
分子名称: Proliferating cell nuclear antigen
著者Housset, D, Frachet, P.
登録日2017-12-20
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.
J.Exp.Med., 216, 2019
2NTI
DownloadVisualize
BU of 2nti by Molmil
Crystal structure of PCNA123 heterotrimer.
分子名称: 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, BROMIDE ION, DNA polymerase sliding clamp A, ...
著者Hlinkova, V, Ling, H.
登録日2006-11-07
公開日2007-12-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
3F1W
DownloadVisualize
BU of 3f1w by Molmil
Crystal structure of a mutant proliferating cell nuclear antigen that blocks translesion synthesis
分子名称: Proliferating cell nuclear antigen
著者Freudenthal, B.D, Ramaswamy, S, Washington, M.T.
登録日2008-10-28
公開日2008-12-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Structure of a Mutant Form of Proliferating Cell Nuclear Antigen That Blocks Translesion DNA Synthesis.
Biochemistry, 47, 2008
2OD8
DownloadVisualize
BU of 2od8 by Molmil
Structure of a peptide derived from Cdc9 bound to PCNA
分子名称: DNA ligase I, mitochondrial precursor, Proliferating cell nuclear antigen
著者Chapados, B.R, Tainer, J.A.
登録日2006-12-21
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase.
Nucleic Acids Res., 35, 2007
7EFA
DownloadVisualize
BU of 7efa by Molmil
Crystal structure of the complex between the C-terminal domain of mouse MUTYH and human PCNA
分子名称: Adenine DNA glycosylase, Proliferating cell nuclear antigen
著者Nakamura, T, Nakabeppu, Y, Yamagata, Y.
登録日2021-03-21
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer.
Nucleic Acids Res., 49, 2021

225158

件を2024-09-18に公開中

PDB statisticsPDBj update infoContact PDBjnumon