8QCI
| FCGBP D10 Assembly Segment | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | 著者 | Yeshaya, N, Fass, D. | 登録日 | 2023-08-27 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | VWD domain stabilization by autocatalytic Asp-Pro cleavage. Protein Sci., 33, 2024
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7KWO
| rFVIIIFc-VWF-XTEN (BIVV001) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COPPER (II) ION, ... | 著者 | Fuller, J.R, Batchelor, J.D. | 登録日 | 2020-12-01 | 公開日 | 2021-03-03 | 最終更新日 | 2021-06-09 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular determinants of the factor VIII/von Willebrand factor complex revealed by BIVV001 cryo-electron microscopy. Blood, 137, 2021
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6TM2
| Human MUC2 AAs 21-1397 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Javitt, G, Khmelnitsky, L, Albert, L, Elad, N, Ilani, T, Diskin, R, Fass, D. | 登録日 | 2019-12-03 | 公開日 | 2020-10-21 | 最終更新日 | 2020-11-11 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Assembly Mechanism of Mucin and von Willebrand Factor Polymers. Cell, 183, 2020
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6RBF
| Mucin 2 D3 domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | 著者 | Javitt, G, Fass, D. | 登録日 | 2019-04-10 | 公開日 | 2019-08-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.704 Å) | 主引用文献 | Intestinal Gel-Forming Mucins Polymerize by Disulfide-Mediated Dimerization of D3 Domains. J.Mol.Biol., 431, 2019
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7A5O
| Human MUC2 AAs 21-1397 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Javitt, G, Khmelnitsky, L, Albert, L, Elad, N, Ilani, T, Diskin, R, Fass, D. | 登録日 | 2020-08-21 | 公開日 | 2020-10-21 | 最終更新日 | 2020-11-11 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Assembly Mechanism of Mucin and von Willebrand Factor Polymers. Cell, 183, 2020
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6N29
| Crystal structure of monomeric von Willebrand Factor D`D3 assembly | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Dong, X, Arndt, J.W, Springer, T.A. | 登録日 | 2018-11-12 | 公開日 | 2019-01-23 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis. Blood, 133, 2019
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1LSH
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8OER
| MUC5B amino acids 26-1435 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mucin-5B | 著者 | Khmelnitsky, L, Fass, D. | 登録日 | 2023-03-12 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Pulmonary Fibrosis Linked to Impaired Mucin 5B Supramolecular Assembly To Be Published
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8OES
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7PP6
| MUC2 Tubules of D1D2D3 domains | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Javitt, G, Fass, D. | 登録日 | 2021-09-13 | 公開日 | 2022-02-16 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules. Proc.Natl.Acad.Sci.USA, 119, 2022
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7POV
| MUC2 Tubules of D1D2D3 domains | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Javitt, G, Fass, D. | 登録日 | 2021-09-10 | 公開日 | 2022-02-16 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules. Proc.Natl.Acad.Sci.USA, 119, 2022
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7PMV
| VWF Tubules of D1D2D'D3 domains | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Javitt, G, Fass, D. | 登録日 | 2021-09-02 | 公開日 | 2022-02-23 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules. Proc.Natl.Acad.Sci.USA, 119, 2022
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7PNF
| VWF Tubules of D1D2D'D3 domains | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Javitt, G, Fass, D. | 登録日 | 2021-09-06 | 公開日 | 2022-02-23 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (4.35 Å) | 主引用文献 | Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules. Proc.Natl.Acad.Sci.USA, 119, 2022
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7PRL
| MUC2 D1 with Cu(II) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, GLYCEROL, ... | 著者 | Reznik, N, Fass, D. | 登録日 | 2021-09-22 | 公開日 | 2022-10-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Intestinal mucin is a chaperone of multivalent copper. Cell, 185, 2022
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7WN6
| Cryo-EM structure of VWF D'D3 dimer (R1136M/E1143M mutant) complexed with D1D2 at 3.29 angstron resolution (2 units) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ... | 著者 | Zeng, J.W, Shu, Z.M, Zhou, A.W. | 登録日 | 2022-01-17 | 公開日 | 2022-05-18 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Structural mechanism of VWF D'D3 dimer formation. Cell Discov, 8, 2022
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7WN4
| Cryo-EM structure of VWF D'D3 dimer (wild type) complexed with D1D2 at 3.4 angstron resolution (1 unit) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ... | 著者 | Zeng, J.W, Shu, Z.M, Zhou, A.W. | 登録日 | 2022-01-17 | 公開日 | 2022-05-18 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural mechanism of VWF D'D3 dimer formation. Cell Discov, 8, 2022
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7WPP
| Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 2.85 angstron resolution (1 unit) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ... | 著者 | Zeng, J.W, Shu, Z.M, Zhou, A.W. | 登録日 | 2022-01-24 | 公開日 | 2022-05-25 | 最終更新日 | 2022-06-15 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Structural basis of von Willebrand factor multimerization and tubular storage. Blood, 139, 2022
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7WPQ
| Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 3.27 angstron resolution (2 units) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ... | 著者 | Zeng, J.W, Shu, Z.M, Zhou, A.W. | 登録日 | 2022-01-24 | 公開日 | 2022-05-25 | 最終更新日 | 2022-06-15 | 実験手法 | ELECTRON MICROSCOPY (3.267 Å) | 主引用文献 | Structural basis of von Willebrand factor multimerization and tubular storage. Blood, 139, 2022
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7WQT
| Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 4.3 angstron resolution (VWF tube) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ... | 著者 | Zeng, J.W, Shu, Z.M, Zhou, A.W. | 登録日 | 2022-01-26 | 公開日 | 2022-05-25 | 最終更新日 | 2022-06-15 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis of von Willebrand factor multimerization and tubular storage. Blood, 139, 2022
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7WPS
| Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 4.3 angstron resolution (7 units) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ... | 著者 | Zeng, J.W, Shu, Z.M, Zhou, A.W. | 登録日 | 2022-01-24 | 公開日 | 2022-05-25 | 最終更新日 | 2022-06-15 | 実験手法 | ELECTRON MICROSCOPY (4.32 Å) | 主引用文献 | Structural basis of von Willebrand factor multimerization and tubular storage. Blood, 139, 2022
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7WN3
| Cryo-EM structure of VWF D'D3 dimer (2M mutant) complexed with D1D2 at 3.29 angstron resolution (2 units) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ... | 著者 | Zeng, J.W, Shu, Z.M, Zhou, A.W. | 登録日 | 2022-01-17 | 公開日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Structural mechanism of VWF D'D3 dimer formation. Cell Discov, 8, 2022
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7WPR
| VWF D'D3 dimer complexed with D1D2 at 4.39 angstron resolution(VWF tube) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ... | 著者 | Zeng, J.W, Shu, Z.M, Zhou, A.W. | 登録日 | 2022-01-24 | 公開日 | 2022-05-25 | 最終更新日 | 2022-06-15 | 実験手法 | ELECTRON MICROSCOPY (4.39 Å) | 主引用文献 | Structural basis of von Willebrand factor multimerization and tubular storage. Blood, 139, 2022
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7QCU
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7QCL
| Structure of the MUCIN-2 Cterminal domains | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mucin-2, ... | 著者 | Gallego, P, Hansson, G.C. | 登録日 | 2021-11-24 | 公開日 | 2023-03-08 | 最終更新日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming mucins. Nat Commun, 14, 2023
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7QCN
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