PDB: 85 件ウェブページステータス検索Chemie searchBIRD

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1ZTX	West Nile Virus Envelope Protein DIII in complex with neutralizing E16 antibody Fab 分子名称: Envelope protein, Heavy Chain of E16 Antibody, Light Chain of E16 Antibody 著者 Nybakken, G.E, Oliphant, T, Diamond, M.S, Fremont, D.H. 登録日 2005-05-27 公開日 2005-10-04 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis of West Nile virus neutralization by a therapeutic antibody. Nature, 437, 2005
2I69	Crystal structure of the West Nile virus envelope glycoprotein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Polyprotein 著者 Kanai, R, Modis, Y. 登録日 2006-08-28 公開日 2006-11-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Crystal structure of west nile virus envelope glycoprotein reveals viral surface epitopes. J.Virol., 80, 2006
8UTG	An RNA G-Quadruplex from the NS5 gene in the West Nile Virus Genome 分子名称: AMMONIUM ION, POTASSIUM ION, RNA (5'-R(*UP*AP*UP*GP*GP*AP*AP*GP*AP*GP*GP*CP*GP*GP*UP*UP*GP*GP*UP*AP*U)-3') 著者 Terrell, J.R, Le, T.T, Wilson, W.D, Siemer, J.L. 登録日 2023-10-31 公開日 2024-06-19 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structure of an RNA G-quadruplex from the West Nile virus genome. Nat Commun, 15, 2024
1S6N	NMR Structure of Domain III of the West Nile Virus Envelope Protein, Strain 385-99 分子名称: envelope glycoprotein 著者 Volk, D.E, Beasley, D.W, Kallick, D.A, Holbrook, M.R, Barrett, A.D, Gorenstein, D.G. 登録日 2004-01-26 公開日 2004-07-06 最終更新日 2011-07-13 実験手法 SOLUTION NMR 主引用文献 Solution Structure and Antibody Binding Studies of the Envelope Protein Domain III from the New York Strain of West Nile Virus J.Biol.Chem., 279, 2004
3IYW	West Nile virus in complex with Fab fragments of MAb CR4354 (fitted coordinates of envelope proteins and Fab fragments of one icosahedral ASU) 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-alpha-D-glucopyranose, CR4354 Fab fragment X1, heavy chain H, ... 著者 Rossmann, M.G, Kaufmann, B. 登録日 2010-06-18 公開日 2010-11-24 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (13.7 Å) 主引用文献 Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354. Proc.Natl.Acad.Sci.USA, 107, 2010
2OF6	Structure of immature West Nile virus 分子名称: envelope glycoprotein E 著者 Zhang, Y, Kaufmann, B, Chipman, P.R, Kuhn, R.J, Rossmann, M.G. 登録日 2007-01-02 公開日 2007-04-03 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (24 Å) 主引用文献 Structure of immature west nile virus. J.Virol., 81, 2007
2FP7	West Nile Virus NS2B/NS3protease in complex with Bz-Nle-Lys-Arg-Arg-H 分子名称: Genome polyprotein, N-benzoyl-L-norleucyl-L-lysyl-N-[(2S)-5-carbamimidamido-1-hydroxypentan-2-yl]-L-argininamide 著者 Schiering, N, D'Arcy, A, Erbel, P. 登録日 2006-01-16 公開日 2006-03-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus. Nat.Struct.Mol.Biol., 13, 2006
2HG0	Structure of the West Nile Virus envelope glycoprotein 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein 著者 Nybakken, G.E, Nelson, C.A, Chen, B.R, Diamond, M.S, Fremont, D.H. 登録日 2006-06-26 公開日 2006-11-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the West Nile virus envelope glycoprotein. J.Virol., 80, 2006
2YOL	West Nile Virus NS2B-NS3 protease in complex with 3,4- dichlorophenylacetyl-Lys-Lys-GCMA 分子名称: (S)-6-amino-N-((S)-6-amino-1-(((1r,4S)-4-guanidinocyclohexyl)methylamino)-1-oxohexan-2-yl)-2-(2-(3,4-dichlorophenyl)acetamido)hexanamide, CHLORIDE ION, NICKEL (II) ION, ... 著者 Hammamy, M.Z, Haase, C, Hammami, M, Hilgenfeld, R, Steinmetzer, T. 登録日 2012-10-25 公開日 2013-03-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Development and Characterization of New Peptidomimetic Inhibitors of the West Nile Virus Ns2B-Ns3 Protease. Chemmedchem, 8, 2013
1SFK	Core (C) protein from West Nile Virus, subtype Kunjin 分子名称: CALCIUM ION, CHLORIDE ION, Core protein, ... 著者 Dokland, T, Walsh, M, Mackenzie, J.M, Khromykh, A.A, Ee, K.-H, Wang, S. 登録日 2004-02-19 公開日 2004-08-09 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 West nile virus core protein; tetramer structure and ribbon formation Structure, 12, 2004
6U79	Solution NMR structure of 5' UTR stem loop B from West Nile Virus 分子名称: 5' UTR region stem loop 著者 Sharma, S, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-09-01 公開日 2020-08-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR structure of Dengue West Nile viruses stem-loop B: A key cis-acting element for flavivirus replication. Biochem.Biophys.Res.Commun., 531, 2020
4TPL	West Nile Virus Non-structural protein 1 (NS1) Form 1 crystal 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, OXTOXYNOL-10, ... 著者 Akey, D.L, Smith, J.L. 登録日 2014-06-08 公開日 2014-10-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Use of massively multiple merged data for low-resolution S-SAD phasing and refinement of flavivirus NS1. Acta Crystallogr.,Sect.D, 70, 2014
8CO8	Structure of West Nile Virus NS2B-NS3 protease 分子名称: Serine protease subunit NS2B,Serine protease/Helicase NS3 著者 Fairhead, M, Godoy, A.S, Koekemoer, L, Balcomb, B.H, Lithgo, R.M, Aschenbrenner, J.C, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Fearon, D, Walsh, M.A, von Delft, F. 登録日 2023-02-27 公開日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structure of West Nile Virus NS2B-NS3 protease - to be published To Be Published
2P5P	Crystal Structure Analysis of the West Nile virus envelope (E) protein domain III 分子名称: Genome polyprotein 著者 Gao, F, Yuan, F, Gao, G.F. 登録日 2007-03-16 公開日 2008-03-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure Analysis of the West Nile virus envelope (E) protein domain III To be Published
3E90	West Nile vi rus NS2B-NS3protease in complexed with inhibitor Naph-KKR-H 分子名称: NS2B cofactor, NS3 protease, N~2~-(naphthalen-2-ylcarbonyl)-L-lysyl-N-[(1S)-4-carbamimidamido-1-formylbutyl]-L-lysinamide 著者 Martin, J.L, Robin, G. 登録日 2008-08-21 公開日 2009-01-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation J.Mol.Biol., 385, 2009
3N9G	Crystal structure of the Fab fragment of the human neutralizing anti-West Nile Virus MAb CR4354 分子名称: Fab fragment of MAb CR4354, heavy chain, light chain 著者 Kaufmann, B, Rossmann, M.G. 登録日 2010-05-29 公開日 2010-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.434 Å) 主引用文献 Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354. Proc.Natl.Acad.Sci.USA, 107, 2010
2OY0	Crystal structure of the West Nile virus methyltransferase 分子名称: Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Li, H.M, Zhao, Y.W, Guo, Y, Shi, P.Y. 登録日 2007-02-21 公開日 2007-04-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure and Function of Flavivirus NS5 Methyltransferase. J.Virol., 81, 2007
2GGV	Crystal structure of the West Nile virus NS2B-NS3 protease, His51Ala mutant 分子名称: non-structural protein 2B, non-structural protein 3 著者 Aleshin, A.E, Shiryaev, S.A, Strongin, A.Y, Liddington, R.C. 登録日 2006-03-24 公開日 2007-03-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold. Protein Sci., 16, 2007
5IDK	Crystal structure of West Nile Virus NS2B-NS3 protease in complex with a capped dipeptide boronate inhibitor 分子名称: ((R)-1-((S)-3-(4-(aminomethyl)phenyl)-2-benzamidopropaneamido)-4-guanidinobutyl)boronic acid, cyclic double ester with glycerol, DIMETHYL SULFOXIDE, ... 著者 Hilgenfeld, R, Zhang, L. 登録日 2016-02-24 公開日 2016-12-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Peptide-Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology. J. Med. Chem., 60, 2017
3I50	Crystal structure of the West Nile Virus envelope glycoprotein in complex with the E53 antibody Fab 分子名称: Envelope glycoprotein, murine heavy chain (IgG3) of E53 monoclonal antibody Fab, murine kappa light chain of E53 monoclonal antibody Fab 著者 Nybakken, G.E, Warren, J.T, Chen, B.R, Nelson, C.A, Fremont, D.H. 登録日 2009-07-03 公開日 2009-10-27 最終更新日 2013-09-25 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody. Embo J., 28, 2009
2HCN	Crystal structure of RNA dependent RNA polymerase domain from west nile virus 分子名称: CALCIUM ION, RNA-directed RNA polymerase (NS5), ZINC ION 著者 Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP) 登録日 2006-06-17 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5 J.Biol.Chem., 282, 2007
2HFZ	Crystal structure of RNA dependent RNA polymerase domain from West Nile virus 分子名称: MAGNESIUM ION, RNA-directed RNA polymerase(NS5), ZINC ION 著者 Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP) 登録日 2006-06-26 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5 J.Biol.Chem., 282, 2007
2HCS	Crystal structure of RNA dependant RNA polymerase domain of West Nile virus 分子名称: RNA-directed RNA polymerase (NS5), ZINC ION 著者 Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP) 登録日 2006-06-18 公開日 2007-02-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5 J.Biol.Chem., 282, 2007
2IJO	Crystal Structure of the West Nile virus NS2B-NS3 protease complexed with bovine pancreatic trypsin inhibitor 分子名称: Pancreatic trypsin inhibitor, Polyprotein 著者 Aleshin, A.E, Shiryaev, S.A, Strongin, A.Y, Liddington, R.C. 登録日 2006-09-29 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold. Protein Sci., 16, 2007
2FOM	Dengue Virus NS2B/NS3 Protease 分子名称: CHLORIDE ION, GLYCEROL, polyprotein 著者 Schiering, N, Kroemer, M, Renatus, M, Erbel, P, D'Arcy, A. 登録日 2006-01-13 公開日 2006-03-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus. Nat.Struct.Mol.Biol., 13, 2006

 

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