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1HZF
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BU of 1hzf by Molmil
C4ADG FRAGMENT OF HUMAN COMPLEMENT FACTOR C4A
Descriptor: COMPLEMENT FACTOR C4A
Authors:van den Elsen, J.M.H, Martin, A, Wong, V, Clemenza, L, Rose, D.R, Isenman, D.E.
Deposit date:2001-01-24
Release date:2002-10-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray crystal structure of the C4d fragment of human complement component C4.
J.Mol.Biol., 322, 2002
1QSJ
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BU of 1qsj by Molmil
N-TERMINALLY TRUNCATED C3DG FRAGMENT
Descriptor: COMPLEMENT C3 PRECURSOR
Authors:Zanotti, G, Bassetto, A, Battistutta, R, Stoppini, M, Folli, C, Berni, R.
Deposit date:1999-06-22
Release date:2000-07-31
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure at 1.44 A resolution of an N-terminally truncated form of the rat serum complement C3d fragment.
Biochim.Biophys.Acta, 1478, 2000
1C3D
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BU of 1c3d by Molmil
X-RAY CRYSTAL STRUCTURE OF C3D: A C3 FRAGMENT AND LIGAND FOR COMPLEMENT RECEPTOR 2
Descriptor: C3D, GLYCEROL
Authors:Nagar, B, Jones, R.G, Diefenbach, R.J, Isenman, D.E, Rini, J.M.
Deposit date:1998-05-19
Release date:1998-10-07
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structure of C3d: a C3 fragment and ligand for complement receptor 2.
Science, 280, 1998
1QQF
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BU of 1qqf by Molmil
N-TERMINALLY TRUNCATED C3D,G FRAGMENT OF THE COMPLEMENT SYSTEM
Descriptor: PROTEIN (COMPLEMENT C3DG)
Authors:Zanotti, G, Bassetto, A, Battistutta, R, Stoppini, M, Berni, R.
Deposit date:1999-06-04
Release date:2000-07-31
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure at 1.44 A resolution of an N-terminally truncated form of the rat serum complement C3d fragment.
Biochim.Biophys.Acta, 1478, 2000
7UE9
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BU of 7ue9 by Molmil
Structure of anti-C3d Fab(3d8b) in complex with C3d
Descriptor: Complement C3dg fragment, Fab heavy chain, Fab light chain, ...
Authors:Olland, A.M, White, A, Suto, R.K.
Deposit date:2022-03-21
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Development and Optimization of Bifunctional Fusion Proteins to Locally Modulate Complement Activation in Diseased Tissue.
Front Immunol, 13, 2022
2NOJ
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BU of 2noj by Molmil
Crystal structure of Ehp / C3d complex
Descriptor: Complement C3, Efb homologous protein
Authors:Hammel, M, Geisbrecht, B.V.
Deposit date:2006-10-25
Release date:2007-08-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Characterization of Ehp, a Secreted Complement Inhibitory Protein from Staphylococcus aureus.
J.Biol.Chem., 282, 2007
2WY7
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BU of 2wy7 by Molmil
Staphylococcus aureus complement subversion protein Sbi-IV in complex with complement fragment C3d revealing an alternative binding mode
Descriptor: COMPLEMENT C3D FRAGMENT, GLYCEROL, IGG-BINDING PROTEIN
Authors:Clark, E.A, Crennell, S, Upadhyay, A, Mackay, J.D, Bagby, S, van den Elsen, J.M.
Deposit date:2009-11-13
Release date:2010-12-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Structural Basis for Staphylococcal Complement Subversion: X-Ray Structure of the Complement- Binding Domain of Staphylococcus Aureus Protein Sbi in Complex with Ligand C3D.
Mol.Immunol., 48, 2011
2WY8
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BU of 2wy8 by Molmil
Staphylococcus aureus complement subversion protein Sbi-IV in complex with complement fragment C3d
Descriptor: COMPLEMENT C3D FRAGMENT, GLYCEROL, IGG-BINDING PROTEIN
Authors:Clark, E.A, Crennell, S, Upadhyay, A, Mackay, J.D, Bagby, S, van den Elsen, J.M.
Deposit date:2009-11-13
Release date:2010-12-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Structural Basis for Staphylococcal Complement Subversion: X-Ray Structure of the Complement- Binding Domain of Staphylococcus Aureus Protein Sbi in Complex with Ligand C3D.
Mol.Immunol., 48, 2011
6RMT
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Crystal structure of disulphide-linked human C3d dimer
Descriptor: CHLORIDE ION, Complement C3
Authors:Wahid, A.A, van den Elsen, J.M.H, Crennell, S.J.
Deposit date:2019-05-07
Release date:2020-11-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insights Into the Structure-Function Relationships of Dimeric C3d Fragments.
Front Immunol, 12, 2021
3D5R
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BU of 3d5r by Molmil
Crystal Structure of Efb-C (N138A) / C3d Complex
Descriptor: Complement C3, Fibrinogen-binding protein
Authors:Geisbrecht, B.V.
Deposit date:2008-05-16
Release date:2008-09-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d.
Protein Sci., 17, 2008
3D5S
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BU of 3d5s by Molmil
Crystal Structure of Efb-C (R131A) / C3d Complex
Descriptor: Complement C3, Fibrinogen-binding protein
Authors:Geisbrecht, B.V.
Deposit date:2008-05-16
Release date:2008-09-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d.
Protein Sci., 17, 2008
2GOX
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BU of 2gox by Molmil
Crystal structure of Efb-C / C3d Complex
Descriptor: Complement C3, Fibrinogen-binding protein
Authors:Hammel, M, Geisbrecht, B.V.
Deposit date:2006-04-14
Release date:2007-03-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A structural basis for complement inhibition by Staphylococcus aureus.
Nat.Immunol., 8, 2007
6RMU
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BU of 6rmu by Molmil
Crystal structure of disulphide-linked human C3d dimer in complex with Staphylococcus aureus complement subversion protein Sbi-IV
Descriptor: 1,2-ETHANEDIOL, Complement C3, DI(HYDROXYETHYL)ETHER, ...
Authors:Wahid, A.A, van den Elsen, J.M.H, Crennell, S.J.
Deposit date:2019-05-07
Release date:2020-11-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Staphylococcal Complement Evasion Protein Sbi Stabilises C3d Dimers by Inducing an N-Terminal Helix Swap
Front Immunol, 13, 2022
7PI6
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BU of 7pi6 by Molmil
Trypanosoma brucei ISG65 bound to human complement C3d
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, 65 kDa invariant surface glycoprotein, Complement C3dg fragment, ...
Authors:Cook, A.D, Higgins, M.K.
Deposit date:2021-08-19
Release date:2022-07-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor.
Nat Commun, 13, 2022
3G6J
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BU of 3g6j by Molmil
C3b in complex with a C3b specific Fab
Descriptor: CALCIUM ION, Complement C3 alpha chain, Complement C3 beta chain, ...
Authors:Wiesmann, C.
Deposit date:2009-02-06
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement
J.Biol.Chem., 284, 2009
4D94
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BU of 4d94 by Molmil
Crystal Structure of TEP1r
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Le, B.V, Williams, M, Logarajah, S, Baxter, R.H.G.
Deposit date:2012-01-11
Release date:2012-10-17
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular Basis for Genetic Resistance of Anopheles gambiae to Plasmodium: Structural Analysis of TEP1 Susceptible and Resistant Alleles.
Plos Pathog., 8, 2012
5FO7
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BU of 5fo7 by Molmil
Crystal Structure of Human Complement C3b at 2.8 Angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN
Authors:Forneris, F, Wu, J, Xue, X, Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
2A73
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BU of 2a73 by Molmil
Human Complement Component C3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Janssen, B.J.C, Huizinga, E.G, Raaijmakers, H.C.A, Roos, A, Daha, M.R, Nilsson-Ekdahl, K, Nilsson, B, Gros, P.
Deposit date:2005-07-04
Release date:2005-09-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of complement component C3 provide insights into the function and evolution of immunity.
Nature, 437, 2005
8CEM
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BU of 8cem by Molmil
Structure of bovine native C3, re-refinement
Descriptor: Complement C3 alpha chain, Complement C3 beta chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Andersen, G.R, Fredslund, F.
Deposit date:2023-02-02
Release date:2023-04-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of bovine complement component 3 reveals the basis for thioester function.
J Mol Biol, 361, 2006
4E0S
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BU of 4e0s by Molmil
Crystal Structure of C5b-6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C5, ...
Authors:Aleshin, A.E, Stec, B, DiScipio, R, Liddington, R.C.
Deposit date:2012-03-05
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.21 Å)
Cite:Crystal structure of c5b-6 suggests structural basis for priming assembly of the membrane attack complex.
J.Biol.Chem., 287, 2012
1W2S
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BU of 1w2s by Molmil
Solution structure of CR2 SCR 1-2 in its complex with C3d by X-ray scattering
Descriptor: COMPLEMENT C3 PRECURSOR, COMPLEMENT RECEPTOR TYPE 2 PRECURSOR,
Authors:Gilbert, H.E, Hannan, J.P, Holers, V.M, Perkins, S.J.
Deposit date:2004-07-08
Release date:2005-09-29
Last modified:2024-05-08
Method:SOLUTION SCATTERING
Cite:Solution Structure of the Complex between Cr2 Scr 1-2 and C3D of Human Complement: An X-Ray Scattering and Sedimentation Modelling Study.
J.Mol.Biol., 346, 2005
4A5W
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BU of 4a5w by Molmil
Crystal structure of C5b6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C5, ...
Authors:Hadders, M.A, Bubeck, D, Forneris, F, Pangburn, M, Llorca, O, Lea, S.M, Gros, P.
Deposit date:2011-10-28
Release date:2012-03-14
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
Cell Rep., 1, 2012
6TAV
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BU of 6tav by Molmil
Crystal structure of endopeptidase-induced alpha2-macroglobulin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ...
Authors:Gomis-Ruth, F.X, Duquerroy, S, Trapani, S, Marrero, A, Goulas, T, Guevara, T, Andersen, G.A, Sottrup-Jensen, L, Navaza, J.
Deposit date:2019-10-30
Release date:2021-05-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Cryo-EM structures shows the mechanistic basis of pan-peptidase inhibition by human alpha2-macroglobulin
Proc.Natl.Acad.Sci.USA, 2022
2XQW
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Structure of Factor H domains 19-20 in complex with complement C3d
Descriptor: COMPLEMENT C3, COMPLEMENT FACTOR H
Authors:Kajander, T, Lehtinen, M.J, Hyvarinen, S, Bhattacharjee, A, Leung, E, Isenman, D.E, Meri, S, Jokiranta, T.S, Goldman, A.
Deposit date:2010-09-07
Release date:2011-02-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.306 Å)
Cite:Dual Interaction of Factor H with C3D and Glycosaminoglycans in Host-Nonhost Discrimination by Complement.
Proc.Natl.Acad.Sci.USA, 108, 2011
6EHG
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complement component C3b in complex with a nanobody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jensen, R.K, Andersen, K.R, Gadeberg, T.A.F, Laursen, N.S, Andersen, G.R.
Deposit date:2017-09-13
Release date:2018-02-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement.
J. Biol. Chem., 293, 2018

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